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Don Sleeter

@donsleeter.bsky.social

❤️ Physics, Molecular Biology, Automated DNA Sequencing, Bioinformatics, Biomarker Discovery. SwiftUI.

486 Followers  |  385 Following  |  8 Posts  |  Joined: 08.03.2025  |  1.6389

Latest posts by donsleeter.bsky.social on Bluesky

Ice? Not Ice!

10.06.2025 17:42 — 👍 2    🔁 0    💬 0    📌 0
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25 years ago, I led the development of software for human review of automated DNA sequencing projects at scale. Many genomes, many labs, fast and secure analysis. At Incyte Genomics. For HGRI and the Stanford human genome project.

26.03.2025 22:21 — 👍 5    🔁 0    💬 0    📌 0

I had this idea in 1979-80, and made a few notes of music from rrnB operon sequences back then when working in Harry Noller’s lab — one of the first DNA sequencing labs. We didn’t have any software back then. Proofreading was Jurgen and I reading it back to each other. I wanted music to help.

26.03.2025 22:14 — 👍 1    🔁 0    💬 0    📌 0

Not weird in a bad way.

26.03.2025 22:06 — 👍 0    🔁 0    💬 0    📌 0

Well, except Nick, here, being a “designer”.

26.03.2025 22:03 — 👍 1    🔁 0    💬 0    📌 0

Flowers “run” on algorithms of gene expression which is run on patterns in RNA-protein complexes responding to environmental cues. Precise microscopic mechanisms in a sea of chaos. Purpose and beauty emerging from randomness. No designer. Just physics and mathematics as “the rules.”

26.03.2025 21:59 — 👍 0    🔁 0    💬 1    📌 0

Nick: I encourage your work directions. Big fan.

26.03.2025 21:58 — 👍 0    🔁 0    💬 0    📌 0

Hey, i was wondering what CycleBar was like inside. You answered my question. Leadership demonstrated. I’ll go in for my first spin. Yet another form of Swalwelling.

24.03.2025 07:04 — 👍 0    🔁 0    💬 0    📌 0

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