Nicky O’Boyle

Thanks Aoife!

The glucose uptake inhibitor SgrS is induced by D-serine yet does not contribute to growth arrest in enterohaemorrhagic Escherichia coli Bacterial pathogens sense and respond to host-derived metabolites to regulate virulence and establish successful infections. d-Serine, an amino acid abundant in some extraintestinal environments but s...

Delighted to share the hard work of undergraduate student Ella Rellis and first publication from my group since relocating to TCD. Here we identify a new stress response regulator induced by D-serine. 🦠🔬🧫 @microbiologysociety.org #publishforthecommunity www.microbiologyresearch.org/content/jour...

Investigating the role of the Vi antigen in Salmonella pathogenesis. at University of Edinburgh on FindAPhD.com PhD Project - Investigating the role of the Vi antigen in Salmonella pathogenesis. at University of Edinburgh, listed on FindAPhD.com

If you’re interested in solving bacterial mysteries, this PhD project is for you!

www.findaphd.com/phds/project...

👏🎉 Congrats Aalap et al. #publishforthecommunity @microbiologysociety.org

Tomorrow is the final day to submit your work for presentation at #Microbio26 in Belfast!
Abstract submissions close at 23:59 GMT on Tuesday 11 November: microb.io/AC26Abstracts

Want to find ways to combat TB? Check out this PhD position 👇

MRC DiMeN Doctoral Training Partnership: Structural and Functional Analysis of Drug Resistance in Tuberculosis via a Novel MmpL3 Binding Site at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Structural and Functional Analysis of Drug Resistance in Tuberculosis via a Novel MmpL3 Binding Site at Newcastle University, listed on FindAPhD....

PhD opportunity with me and @kshbeckham.bsky.social

www.findaphd.com/phds/project...

Fantastic PhD opportunity 👇

The Microbiology Society returns to Belfast in April. From microbiomes to natural products, phage to protists, infection models to plant pathogens, together with all the usual fora, and ECM development opportunities. There truly is something for everyone! Get your abstracts in now and join us! 🦠

Graphic shows a birdseye view of the Hodson Bay Hotel, Ireland. Title reads 'Microbiology Society Annual Meeting in Ireland. Registration now open'.

Register today for Microbiology Society Annual Meeting in Ireland 2025.

Join us for a one-and-a-half day meeting in Athlone, Ireland for an opportunity to explore current Microbiology research and spark collaboration amongst fellow researchers, educators and early careers.

🚨One week left to apply for this exciting postdoctoral opportunity. 4 year project investigating novel therapeutics targeting IBD-associated pathobionts. Come and join us at TCD Microbiology 🦠🧬🔬

🚨One week left to apply for this PhD opportunity. Come and join us at TCD Microbiology. All fees and full €25000 stipend covered for 4 years.

Looking to appoint a new or experienced Postdoc to join my team. Investigating novel therapeutics targeting Crohn's disease associated bacteria. Background in Microbiology, Immunology, Biochemistry or related field. 🦠🔬

Apply here: my.corehr.com/pls/trrecrui...

Closing date: 31st May 2025

Four year fully funded PhD studentship: Bioprospecting Marine Sponge Streptomyces for Novel Anti-Virulence Therapeutics at Trinity College Dublin on FindAPhD.com PhD Project - Four year fully funded PhD studentship: Bioprospecting Marine Sponge Streptomyces for Novel Anti-Virulence Therapeutics at Trinity College Dublin, listed on FindAPhD.com

Looking to appoint a PhD candidate with background in Microbiology, Biochemistry, Biotechnology or related field to work on discovery of infection combatting therapeutics in marine sponge-associated bacteria. Closing date 31st May 2025. International applications welcomed!🌎

First PhD student of the Rudkin Lab presenting at her first Microbiology Society event. Super proud of how well she's doing. Hope it's the first of many #MicroBio25

Study finds strongest evidence yet that shingles vaccine helps cut dementia risk Older adults in Wales who had the jab were 20% less likely to be diagnosed with dementia that those not vaccinated

Study finds strongest evidence yet that shingles vaccine helps cut dementia risk

Older adults in Wales who had the jab were 20% less likely to be diagnosed with dementia that those not vaccinated

www.theguardian.com/society/2025...

New paper from the group - here we show that aurodox prevents shiga toxin mediated damage in a murine model. Interesting changes to the microbiota too. Amazing work by @rebeccamchugh.bsky.social and the group.

Paper here- rdcu.be/efW0K

Day 2 #microbio25 in sunny Liverpool. The Role of Microbiomes in Humans, Animals and Ecosystems part 2 begins at 10.15 in Hall1B. 🦠🧍🐄 🏜️

The image shows a picture of Lindsay Hall in a yellow top - she will give todays Peter Wildy Lecture at the microbiology society conference

First up at 9am today at #Microbio25 is Prof Lindsay Hall @halllab.bsky.social winner of the Peter Wildy prize, the award recognises excellence in science communication, outreach and engagement in the field of microbiology – congrats Lindsay 🎉

NILAB: EVOLVE-AI: Evolutionary-Informed Deep Learning for Deciphering and Modifying Cell-Cell Communication During Infection, Inflammation, and Cancer at Queen’s University Belfast on FindAPhD.com PhD Project - NILAB: EVOLVE-AI: Evolutionary-Informed Deep Learning for Deciphering and Modifying Cell-Cell Communication During Infection, Inflammation, and Cancer at Queen’s University Belfast, list...

Our final PhD position is now live - come help us see if AI approaches can aid our understanding of cellular signalling systems during infection and cancer. Maybe this could help develop new clinical interventions?

www.findaphd.com/phds/project...

Strain-level variation among vaginal Lactobacillus crispatus and Lactobacillus iners as identified by comparative metagenomics - npj Biofilms and Microbiomes npj Biofilms and Microbiomes - Strain-level variation among vaginal Lactobacillus crispatus and Lactobacillus iners as identified by comparative metagenomics

📣Publication alert!
Another great output from @metagymomics.bsky.social for his PhD. Looking at strain level genetic variation within members of the vaginal microbiome. #microsky @pauldcotter.bsky.social @calumwalsh.bsky.social
www.nature.com/articles/s41...

Packed Moyne Institute Lecture Theatre for @sligomicrobe.bsky.social! Strainspotting in the vaginal microbiome.

CsrA-mediated regulation of a virulence switch in Acinetobacter baumannii | mBio The World Health Organization has ranked Acinetobacter baumannii atop its “priority pathogens” list highlighting the urgent need for new therapeutics against this pathogen. Many A. baumannii strains i...

Our lab contributed to this including @hamrockfergal.bsky.social : CsrA-mediated regulation of a virulence switch in Acinetobacter baumannii. Great work led by Phil Rather's group.

journals.asm.org/doi/10.1128/...

A work that started 10y ago with a simple experiment with a curious result. Great to see it finally published. Massive effort by @nic-ler.bsky.social and Andrew Cameron! Happy to have contributed to this!

UK ‘falling short’ in fight against rise of superbugs resistant to antibiotics Antimicrobial resistance contributing to estimated 35,000 deaths a year in UK, and government ‘a long way’ from containing the problem, says NAO

In UK, antibiotic-resistant bacterial infections in humans have INCREASED by 13% since 2018…

Despite a target to reduce them by 10%.

www.theguardian.com/society/2025...

📣Fully funded PhD position available in our lab at @uniwuerzburg.bsky.social, in collaboration with Dr. Connolly at Newcastle University (@ruamicro.bsky.social). "Dissecting the RNA-centric landscape of microbiota-pathogen interactions in the gut”. 🦠

Apply here: www.uni-wuerzburg.de/karriere/sin...

Congrats Liam! They're lucky to have you! 🎉

The David Holden PhD Studentship in Bacterial Pathogenesis at Imperial College London: Molecular Mechanisms in Bacterial Pathogenesis at Imperial College London on FindAPhD.com PhD Project - The David Holden PhD Studentship in Bacterial Pathogenesis at Imperial College London: Molecular Mechanisms in Bacterial Pathogenesis at Imperial College London, listed on FindAPhD.com

Interested in a PhD in bacterial pathogenesis? Then consider applying to the inaugural David Holden PhD Studentship at Imperial inaugural David Holden PhD Studentship (home funded students only). Deadline Jan 31st! www.findaphd.com/phds/project...

PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University on FindAPhD.com PhD Project - PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University, listed on FindAPhD.com

First post of the year to mark my return from maternity leave :) Excited to share the first open PhD position in my group.
Deadline end of February.
Please spread the word. www.findaphd.com/phds/projectdetails.aspx?PJID=181239

Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation - Nature Microbiology Peptidoglycan released by neighbouring kin or non-kin cell lysis induces physiological changes that protect from a range of stresses, including phage predation.

We found that many bacterial species use exogenous peptidoglycan fragments - released by lysis of neighboring cells - as a general danger signal, triggering a danger response that protects bacteria against many dangers: biofilm formation.

Details here 👇
www.nature.com/articles/s41...