Nicolas Gutierrez-Castellanos

Neuronal networks in the dorsal hippocampus causally regulate rescue behavior in mice dos Santos Correa et al. show that exposure to a stressful context promotes the acquisition of rescue behavior in mice and that the dorsal hippocampus is required for this learning. Calcium imaging re...

Thrilled to share that our first study on the hippocampus’ role in helping behavior in mice is now published in @cp-cellreports.bsky.social! This work was driven by an amazing team in my lab, and marks an important milestone for more exciting studies to come!
www.cell.com/cell-reports...

Are you interested in the neuroscience of social and sexual behavior in health and disease? 🧠
We’re offering a fully funded PhD position at the University of Valencia 🇪🇸 (open to non-EU citizens).
📩 Apply now!

Insular cortex predictions regulate glucose homeostasis Brain-body interactions are essential for physical and emotional homeostasis. The brain uses information from the external world to predict upcoming bodily changes. This process involves interoceptive...

lab preprint! Interopceptive predictions are central to many brain-body interactions theories, but it's unclear if/how they affect bodily physiology. We (fearless Einav Litvak et al) show that insular cortex predictions are essential for glucose homeostasis-THREAD.. www.biorxiv.org/content/10.6...

Cell Type-Specific Hormonal Signaling Configures Hypothalamic Circuits for Parenting Parenting behavior emerges from hormonally sensitive circuits, but how distinct circuit components are affected by, and contribute to, sex and state dependent changes in infant caregiving remains uncl...

New paper alert!!...🤩 Led by @blogeman.bsky.social, we identify how cell type-specific hormonal responses in the hypothalamus tunes parenting behavior in males and females 🐭🧠🍼. Highlights in thread 👇 1/6

www.biorxiv.org/content/10.6...

The neuronal circuits and cellular encoding of thermosensation - Nature Reviews Neuroscience The thermosensory system across insects and mammals has shared principles of neuronal wiring and encoding. In this Review, Carta, Vestergaard and Poulet discuss how the nervous systems of insects and ...

New review out! 🔥🧊
We break down how rodents, primates & insects encode temperature in Nature Reviews Neuroscience.

Paper: www.nature.com/articles/s41...

View-only: rdcu.be/eThU1

We used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect.

The full study is now online at Cell. @cp-cell.bsky.social

Paper 👉 www.cell.com/cell/fulltex...

Thread for a synopsis 👉
bsky.app/profile/alex...

3 Postdoctoral Research Fellows Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr.

🚨Job alert🚨

The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour

This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"

euraxess.ec.europa.eu/jobs/383909

Integration of hunger and hormonal state gates infant-directed aggression - Nature Combined behavioural, circuit-level and cellular approaches are used to demonstrate how hypothalamic neurons integrate hunger and oestrous state to drive a switch in how female mice interact with pups...

Out today in Nature: We uncover a neural mechanism for the integration of two internal states - hunger and estrous state - and how this integration shapes pup-directed behaviors in mice.
www.nature.com/articles/s41...

Very excited to announce our latest paper uncovering circuit, cellular and molecular mechanisms underlying the formation and maintenance of social hierarchy, another terrific collaboration with @neurovenki.bsky.social, Vic Kapoor and Adam Nelson (not on bsky) www.sciencedirect.com/science/arti...

A hypothalamic circuit that modulates feeding and parenting behaviours - Nature Single-cell transcriptomic analysis of mouse hypothalamus and behavioural experiments show that specific hypothalamic networks regulate conflicting feeding versus parenting behaviours of female mice.

How do animals decide if they should forage for food or stay home to take care of newborn offspring? Whose needs come first? For my PhD work now out in Nature, we examined how hunger and parenting neurons interact and are reshaped postpartum in mice 🧵⬇️ www.nature.com/articles/s41...

Thrilled to announce that my proposal to further investigate the neural basis of sexual rejection has been funded by the Spanish Ministry for Science and Innovation through the Projects for Knowledge Generation call! Exciting times ahead!
@ageinves.bsky.social

Excellent EBBS 2025 plenary by Inbal Goshen @inbalgoshen.bsky.social
“Astrocytes are beautiful and smart, too” - convinced ✅
@ebbsociety.bsky.social

Excited to share our latest review on the neural mechanisms regulating female sexual behavior—co-authored with the brilliant PhD student Ines Dias, Constanze Lenschow and Susana Lima. Check it out!

I'm thrilled to be part of this incredible symposium. Looking forward to seeing everyone in Bordeaux soon!

🧠 🍄 ⚡️🐭

Now published in @natneuro.nature.com

Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility

nature.com/articles/s4159…

Social Plasticity Lab Understanding the neural basis of flexible social behavior

However... Exciting news! it’s time for the next chapter. I’m thrilled to share the launch of my new lab in the University of Valencia!

socialplasticity.wordpress.com

After an incredible postdoc journey at Champalimaud Research, full of great science and inspiring mentors and colleagues, this week it is officially time to say goodbye to this amazing place

As the Canadian Association for Neuroscience meeting approaches, we are still offering subsidies for Childcare, Dependent, or Disability Care.
Please apply or share with others who may benefit: can-acn.org/meeting-2025...

Stochastic activity in low-rank recurrent neural networks https://www.biorxiv.org/content/10.1101/2025.04.22.649933v1

Annual Meeting of the International Behavioral Neuroscience Society (IBNS), June 24-29, in Tromso, Norway. @ibnsconnect.bsky.social

Registration open for UK Neural Computation 2025 @Imperial neuralcomputation.uk/registration...

ECR day: 9 July, ~30 free places
Main meeting: 10-11 July

Pls share!

Sponsors @aria-research.bsky.social @crick.ac.uk

Organisers: @danakarca.bsky.social @neuralreckoning.bsky.social & me

Stereo olfaction underlies stable coding of head direction in blind mice - Nature Communications Stereo olfaction involves comparing odor differences between the two nostrils. Here, using neuronal recordings and a behavioral test, the authors demonstrate that blind mice use stereo olfaction to fo...

🚨new paper alert
Blind mice use stereo olfaction, comparing smells between nostrils, to maintain a stable sense of direction. Blocking this ability disrupts their internal compass.

Kudos to @kasumbisa.bsky.social! Another cool chapter of the Trenholm-Peyrache collab😉

www.nature.com/articles/s41...

A neuroimmune circuit mediates cancer cachexia-associated apathy Cachexia, a severe wasting syndrome associated with inflammatory conditions, often leads to multiorgan failure and death. Patients with cachexia experience extreme fatigue, apathy, and clinical depres...

1/ Why do patients with late-stage cancer lose motivation & sink into apathy?
🔥 Our new Science paper shows chronic inflammation activates a cytokine-sensing brain circuit that lowers motivation. Huge team effort: Aelita Zhu, Sarah Starosta, Pignatelli & Janowitz labs! 🧵
🔗 doi.org/10.1126/scie...

Postdoctoral research position in Institut Pasteur

🚨 JOB OFFER in our lab at Institut Pasteur 🚨
We are looking for a postdoc! Please repost 🙏

BlueBerry Wireless Optogenetics BlueBerry is a multi-channel wireless optogenetic system for freely moving mice and rats.

Kicking off Bluesky with BlueBerry, our open-access, multichannel wireless optogenetic device for freely moving rodents. Visit www.OptoBlueBerry.org for documentation and see its neuroscience applications from large-scale to social settings in our recent preprint: www.biorxiv.org/content/10.1... ​

This is so cool!

(1/n) Why is it so hard to stop eating when something tastes amazing? Our new @ science.org paper reveals that dopamine helps sustain our drive for tasty treats—and may explain how anti-obesity Ozempic tames those urges. doi.org/10.1126/science.adt0773

Long thought to have little relevance to ovarian physiology, the rete ovarii may have a role in follicular dynamics and reproductive health.
buff.ly/JhwpURU