amelie-iska's Avatar

amelie-iska

@amelie-iska.bsky.social

(She/her) I โค๏ธproteins! Iโ€™m an AI researcher and budding in silico molecular engineer focused mostly on proteins and small molecules. Intersex=awesome ๐Ÿ˜Ž๐Ÿณ๏ธโ€๐ŸŒˆ๐Ÿณ๏ธโ€โšง๏ธโšง๏ธ๐Ÿ’ป๐ŸŽฏ๐Ÿงฌ๐Ÿงซ๐Ÿฆ ๐Ÿ”ฌโš—๏ธ๐Ÿงช๐Ÿ’Š๐Ÿ’‰โœก๏ธ๐Ÿชฌ

1,928 Followers  |  786 Following  |  154 Posts  |  Joined: 08.10.2024  |  2.1597

Latest posts by amelie-iska.bsky.social on Bluesky

The following is an "old" idea that is being implemented more and more in newer models and I believe it allows for "adjusting the creativity" of models by sampling in proportion to a distribution instead of seeking maximal rewards as is done in traditional reinforcement learning.

11.08.2025 15:30 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Generative Flow Networks - Yoshua Bengio (see gflownet tutorial and paper list here) I have rarely been as enthusiastic about a new research direction. We call them GFlowNets, for Generative Flowโ€ฆ

Could you do a followup video on how the following may factor in? Models are only now being implemented with such methods, and I'm curious to know you opinions on such things. Granted it would require a bit of research and math, but nothing too difficult.

yoshuabengio.org/2022/03/05/g...

11.08.2025 15:30 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Elon Musk posts Nazi-related puns after backlash over inauguration gesture
YouTube video by NBC News Elon Musk posts Nazi-related puns after backlash over inauguration gesture

youtu.be/gDkuwRx14hQ

26.01.2025 17:00 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Musk has been backing neo-Nazi parties around the world
YouTube video by Senator Bernie Sanders Musk has been backing neo-Nazi parties around the world

youtu.be/7ZObMDPR7CQ

25.01.2025 17:49 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Bacteria Build Strange Bridges to Communicate and We've Never Seen It Before
YouTube video by Anton Petrov Bacteria Build Strange Bridges to Communicate and We've Never Seen It Before

youtu.be/kSGW8DmrWlU

21.01.2025 17:17 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
California Wildfires Are An Insurance Nightmare
YouTube video by LegalEagle California Wildfires Are An Insurance Nightmare

Yes, insurance companies really did cancel fire insurance for Californians 2 months before the LA fires.

www.youtube.com/watch?v=5h1H...

17.01.2025 16:18 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
'Fire Tornado' flares up in Palisades Fire
YouTube video by ABC7 'Fire Tornado' flares up in Palisades Fire

youtube.com/shorts/hY2hz...

14.01.2025 19:46 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Changing names puts transgender Californians at risk. New protections could be on the way A new transgender privacy bill in California would make official name changes confidential.

Did you know that court docs for name and gender changes are not confidential? You can google a trans personโ€™s current name and find their old, dead name โ€” and vice versa. In CA, my amazing bud Hazel is working to fix this, and she may just be successful. My latest for @sfchronicle.com

Gift Link ๐ŸŽ

11.01.2025 15:56 โ€” ๐Ÿ‘ 73    ๐Ÿ” 24    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
The California Fires Are Awful
YouTube video by penguinz0 The California Fires Are Awful

youtu.be/0guLkMlb9q4?...

10.01.2025 06:06 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Watch Duty - Wildfire Maps & Alerts Watch Duty, a 501(c)(3) nonprofit, alerts you of nearby wildfires and firefighting efforts in real-time.

Pretty amazing that nonprofit Watch Duty -- which says it has 150 volunteers working around the clock to track wildfires -- has become the most trusted source of information on LA fires. Operated by retired/volunteer firefighters, dispatchers, and reporters. Real people.

www.watchduty.org

09.01.2025 18:18 โ€” ๐Ÿ‘ 1822    ๐Ÿ” 713    ๐Ÿ’ฌ 29    ๐Ÿ“Œ 63

If youโ€™re in LA, stay safe, leave if youโ€™re told to. Sending good vibes.

09.01.2025 07:49 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Treasury Sanctions Entities in Iran and Russia That Attempted to Interfere in the U.S. 2024 Election WASHINGTON โ€“ Today, the Department of the Treasuryโ€™s Office of Foreign Assets Control (OFAC) is designating a subordinate organization of Iranโ€™s Islamic Revolutionary Guard Corps (IRGC), and a Moscow-...

As if anyone had any doubt.

home.treasury.gov/news/press-r...

01.01.2025 17:25 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Learning Equivariant Non-Local Electron Density Functionals | Nicholas Gao
YouTube video by Valence Labs Learning Equivariant Non-Local Electron Density Functionals | Nicholas Gao

youtu.be/3tIWDOjOlYE?...

29.12.2024 14:53 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Okayโ€ฆdensity matrices/operators I can do.

29.12.2024 14:50 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

So, DFT is pretty interesting ๐Ÿ’€

26.12.2024 16:31 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
OpenAI o3 Breakthrough High Score on ARC-AGI-Pub OpenAI o3 scores 75.7% on ARC-AGI public leaderboard.

Well ARC-AGI was cracked by OpenAI with "o3"
arcprize.org/blog/oai-o3-...

20.12.2024 23:15 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Whatโ€™s the paper title?! ๐Ÿ˜ฑ

17.12.2024 00:01 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

If people find MSA subsampling useful, they will likely find MDGen very useful and they will definitely find BioEmu useful.

15.12.2024 05:57 โ€” ๐Ÿ‘ 10    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

bsky.app/profile/kevi...

15.12.2024 05:52 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

wdym? There are many people working on this stuff.

15.12.2024 05:52 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Scouting Frontiers in AI for Biology: Dynamics, Diffusion, and Design, with Amelie Schreiber
YouTube video by Cognitive Revolution "How AI Changes Everything" Scouting Frontiers in AI for Biology: Dynamics, Diffusion, and Design, with Amelie Schreiber

Just nerding out over AI4Biochem with @nathanlabenz.bsky.social

www.youtube.com/watch?v=enNr...

14.12.2024 22:06 โ€” ๐Ÿ‘ 14    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Yo!!! Thank you so much!

14.12.2024 16:38 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Physical Sciences HSI Cluster Assistant Professor in Chemistry & Biochemistry University of California, Los Angeles is hiring. Apply now!

UCLA Chem & Biochem is looking for an assistant professor who has "outstanding potential as a scientist, educator, & mentor to students from groups under-represented in the physical sciences". This is part of a cluster hire in physical sciences. @chemjobber.bsky.social recruit.apo.ucla.edu/JPF10039

09.12.2024 20:11 โ€” ๐Ÿ‘ 16    ๐Ÿ” 15    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
YouTube Share your videos with friends, family, and the world

Immunotherapy for oncology
New more effective & cheap anti-venoms
Allosteric switch proteins
New Alzheimerโ€™s treatments
De novo functional nanopores
Vaccines
And so much more from Baker Lab. Thank you for being such an inspiration and for forging a path forward. ๐Ÿš€๐Ÿ’œ

www.youtube.com/live/HnT1VWz...

09.12.2024 20:43 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@sciencestanley.bsky.social

07.12.2024 04:20 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Iโ€™m trying to figure out how to retrain DiffAbXL, and they trained on SAbDabโ€ฆwould this be useful for splitting that dataset into train/validation/test sets?

07.12.2024 04:18 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
A penultimate classification of canonical antibody CDR conformations Antibody complementarity determining regions (CDRs) are loops within antibodies responsible for engaging antigens during the immune response and in antibody therapeutics and laboratory reagents. Since...

Thanks! Also check our update to CDR clustering where we modified the D score as max over all dihedral distances including omega, instead of average. Also electron density cutoff to detect peptide flips. Eliminated lots of small CDR clusters with poor density. www.biorxiv.org/content/10.1...

07.12.2024 04:15 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Anthropic needs to get on fine tuning Claude with tree of thought reasoning and GFlowNets.

07.12.2024 02:54 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
YouTube Share your videos with friends, family, and the world

Easy to find linkโ€ฆ

www.youtube.com/live/HnT1VWz...

07.12.2024 00:40 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

What big outstanding problems do you foresee being solved in the next 5 years, and which do you think will take longer? And why?

Sending love and good vibesโ€ฆyou all kick ass!

๐Ÿ’œ๐Ÿ”ฅ๐Ÿš€

06.12.2024 23:56 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@amelie-iska is following 20 prominent accounts