and reply

jamanetwork.com/journals/jam...

22.07.2025 21:55 — 👍 8    🔁 5    💬 1    📌 0

Furthermore, even when using their approach, the auc of .74 still suggests the biomarker has potential and should be tested in a clinical population - their conclusions dont alter the next steps

22.07.2025 22:21 — 👍 4    🔁 2    💬 0    📌 0

The key issue with their re analysis is the mixing of training and test set - yet we evaluated model performance on an unseen holdout set and report excellent performance (even after addressing their report issues with initial model selection)

22.07.2025 22:18 — 👍 4    🔁 2    💬 1    📌 0

GitHub - DrNahianC/PREDICT_Script: Script for PREDICT Study https://jamanetwork.com/journals/jamaneurology/fullarticle/2829261 Script for PREDICT Study https://jamanetwork.com/journals/jamaneurology/fullarticle/2829261 - DrNahianC/PREDICT_Script

We further directly address their concerns in our GitHub repository
github.com/DrNahianC/PR...

22.07.2025 22:14 — 👍 4    🔁 2    💬 1    📌 0

Predicting Individual Pain Sensitivity Using a Novel Cortical Biomarker Signature This cohort study analyzes electroencephalography data from healthy participants to analyze and validate a cortical biomarker signature for pain, which comprised the measures sensorimotor peak alpha f...

our NIH HEAL initiative funded biomarkers study now out @jama.com JAMA Neurology

open access, open data and code

w/ @drsmschabrun.bsky.social

jamanetwork.com/journals/jam...

27.01.2025 16:43 — 👍 33    🔁 15    💬 3    📌 3