David Seminowicz

A great read featuring kNOw-PAIN co-lead @daspainbrain.bsky.social and collaborator Dr. Eldon Loh! Huge steps for pain research!

rsfMRI of the claustrum in 234 scans in awake marmosets, now in press at @imagingneurosci.bsky.social

like we showed in humans, rats, and mice previously, claustrum has widespread connectivity to the cortex, especially prefrontal, cingulate, and posterior parietal

direct.mit.edu/imag/article...

A lot of hard work over a year went into this. Details to follow when the embargo lifts! What I can say is that good peer review can make a paper much better, even if it takes a year. And these peer reviewers were very helpful and constructive 🙏. You'll be able to read their comments online.

Biophysical simulations of fMRI responses using realistic microvascular models: insights into distinct hemodynamics in humans and mice https://www.biorxiv.org/content/10.1101/2025.10.08.680976v1

Pain Killers - Western University Everyone feels it. Few understand it. The science is finally catching up.

pain research @westernu.ca will continue to grow

www.schulich.uwo.ca/rapport/2025...

@westernknowpain.bsky.social @westernuwin.bsky.social @westernuresearch.bsky.social

Our next speaker for our Meet the Team Talk is Dr. Tommy Chan, the Director of the John H. Kreeft Headache Clinic and an Assistant Clinical Professor at Western University! We'll be starting at 12 with some announcements and updates! To join, visit: knowpain.ca/meettheteam

Embodying the default mode network: self-related processing from an embodied perspective Self-related processes in the default mode network (DMN) have been viewed predominantly through a cognitive lens, often overlooking the embodied dimen…

Our new paper is out in Current Opinion in Behavioral Sciences; a perspective paper on the DMN, titled "Embodying the default mode network: self-related processing from an embodied perspective"
www.sciencedirect.com/science/arti...

Varicella-zoster virus reactivation and the risk of dementia - Nature Medicine Large-scale longitudinal health records reveal consistent association of varicella-zoster virus reactivation with dementia.

Just incredible findings, and a beautifully written paper: www.nature.com/articles/s41... Get your shingrix vaccine! You do not want peripheral neuropathy, and as a bonus you get substantial protection from later development of dementia.

Counting the days to @IASPpain’s World Congress on Pain 2026 in Bangkok? Make the wait easier by revisiting #PAIN’s collection of articles from the 2024 plenary speakers bit.ly/3K7OuT6

wow - and it it's free! great lineup of speakers and topics

It’s official. 🎉Grateful to receive NIH funding for two R01s: one as Sole PI and another in collaboration with UCSD. Thank you to my career mentors and team for their continued support and guidance. @umsomneurosci.bsky.social

New layer-fMRI preprint using simultaneous layer-fMRI with EEG at 7T. Establishing an acquisition and analysis setup to capture layer-fMRI correlates of spontaneous alpha power variations.
By Marsh et al.
doi.org/10.1101/2025...

We are proud to launch what we think is going to be fantastic opportunity for pain neuroscientists and clinicians to learn the foundations of pain neuroscience

looks decent

also improvements in physical function and sleep

What do you think of this preliminary evidence from Tagne et al. in @cp-cellreports.bsky.social showing evidence of dietary prevention of pain chronification? Check out this Editor’s Pick and Qiufu Ma’s comment on #PRF bit.ly/46UsALK

attention pain ECRs: this is a great opportunity

Human dorsal root ganglia neuronal cell line to study nociceptive signaling: a new pipeline for pain therapy. https://www.biorxiv.org/content/10.1101/2025.09.27.674468v1

Authors retract Science paper on controversial fMRI method Several MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted this month.

Science is self correcting. Finally!

Postdoctoral Research Fellowship (286516) | University of Oslo Job title: Postdoctoral Research Fellowship (286516), Employer: University of Oslo, Deadline: Wednesday, October 15, 2025

Please RT
2 new positions in the lab as postdoc & PhD!

Interested in stress, pain, or reward? This project has it all!

We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶

www.jobbnorge.no/en/available...

While Canada plans for another round of CERC hirings (which costs millions); support to retain international talent & support 🇨🇦 researchers may be cut!

Sign this letter to request @markcarneyforpm.bsky.social to stop the proposed cuts to
research & innovation!

Psilocybin ameliorates neuropathic pain-like behaviour in mice and facilitates gabapentin-mediated analgesia https://www.biorxiv.org/content/10.1101/2025.09.15.676273v1

Beyond Circadian: A Yearlong Electroencephalography Study Reveals Hidden Ultralong-term Sleep Cycles https://www.biorxiv.org/content/10.1101/2025.09.14.676090v1

starting now!

Gut microbiota and metabolites drive chronic sickle cell disease pain in mice Brandow et al. describe how the gut microbiome drives chronic sickle cell disease (SCD) pain. SCD guts contain excessive heme catabolites, fewer bacteria that metabolize bilirubin, and low levels of A...

1st paper from Sadler Lab is out!! Highlights: 1) A. muciniphila reverses sickle cell (SCD) pain, 2) fecal transplant from SCD mice induces pain via bilirubin-TRPM2 vagal signaling, 3) BilR+ bacteria less abundant in SCD patient poo, 4) RNAseq on HUMAN nodose ganglia! www.cell.com/cell-host-mi...

Happy to share our recent work attempting to better understand the impact of early life maternal separation on locus coeruleus function. Super proud of first author (the now Dr.) Chayla Vazquez. She brought this idea when she joined in… March 2020… and she carried it through these rough few years!

Excited to share our latest work is up on bioRxiv! Looking at capillary flow speed changes we show that psilocybin prolongs the neurovascular coupling response to a visual stimulus. 🍄🔬🧠🩸

@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social

Preprint:
www.biorxiv.org/content/10.1...

Developing a model of temporomandibular disorder in the common marmoset using nerve growth factor https://www.biorxiv.org/content/10.1101/2025.08.20.671273v1