📢 The BASHH/BHIVA Guidelines on the Use of HIV Pre-exposure Prophylaxis (PrEP) 2025 have been published
Thank you to @bhiva.bsky.social, the writing group, and all contributors for your expertise and dedication.
Access the guidelines here ➡️ bit.ly/4lMe9Ou
Phasing out NIH’s HIV clinical guidelines is flat-out immoral and unethical.
These guidelines drive early diagnosis, ART initiation, and viral suppression—82% linked to care within 30 days, 69% virally suppressed by 6 months.
Removing them puts millions of lives at risk.
wapo.st/3FQovhf
The new NIH director said grants “canceled because they’re DEI [diversity, equity, and inclusion]-based science … [which does] not actually have anything to do with promoting the health of the American people” www.science.org/content/arti...
So let’s take a quick look at some of his past papers… 🧵
I just listened to #TheDaily episode on "On COVID's Wake" with Frances Lee & Stephen Macedo where they make a categorical statement that non-pharmaceutical interventions didn't work during the pandemic. The evidence does not support this categorical claim. 1/
pmc.ncbi.nlm.nih.gov/articles/PMC...
“A UK registered company (GSK), rolling-over to a US administration that shows blatant disregard for human rights, sends a chilling signal to partners & sets a dangerous precedent.
We join other NGOs & activists in expressing our gravest concern with GSK."
www.thelovetank.info/news/pharmadiv
😳😳😳
🧵 Trump’s USAID funding freeze abruptly halted critical global health research, abandoning participants mid-trial. A gross ethical violation. @bachynski.bsky.social & I explain what happened and why it matters @bmj.com . ⬇️
www.bmj.com/content/388/...
Finally I want to highlight the danger of associating drug use with HIV transmission. In the first mentioned JAIDS study, all of the cocaine using participants were undetectable. Furthermore I find the evidence of cocaine being the main driver for the significant difference in LHR to be weak at best
For example, do non-psychoactive non-illicit chemicals have similar interactions with HIV immunology which we will never discover?
Do 'socially accepted' stimulants (with similar structures) like those prescribed for ADHD and narcolepsy face the same studies?
To what extent can scientific research detach itself from societies stigma? I am curious if meth and cocaine were chosen for the cell studies due to the history of HIV incidence in drug users + the negative social capital associated with illicit drugs
Now, I don't want to stigmatise substance use in PLWH (or anyone for that matter) as it is ubiquitous, fun and abstinence does not work. Rather, I want to pose some questions that came up from this.
But, in the paper, and its citations [45-47] there is proven interactions between cocaine and HIV, proven in vivo and in vitro.
pubmed.ncbi.nlm.nih.gov/23251514/
www.nature.com/articles/sre...
And literature suggesting the same for Meth
cellandbioscience.biomedcentral.com/articles/10....
In my training, drugs were always been linked to HIV/STIs through a social epidemiological lens. Chemsex, social status and the systemic marginalisation of illicit drug users tend to come to mind as the primary connection between the two.
So here is a thread of me yapping about this mornings readings and reflections.
I want to talk about HIV and Cocaine.
This morning I stumbled upon a publication linking recent cocaine use in PLWH to increased latent HIV reservoirs. This caught my eye and I was surprised by what the paper suggested and intrigued by its citations.
The paper is: doi.org/10.1101/2022...
Dual Daily HIV and sexually transmitted infection pre-exposure prophylaxis using tenofovir disoproxil fumarate/emtricitabine and doxycycline in gay, bisexual and other men who have sex with men and transgender women: The DuDHS Study
✅ Just Accepted
#IDSky
Want to shape the future of DoxyPEP provision in the UK?
Take part in the @bashhuk.bsky.social public consultation for new DoxyPEP guidelines.
Take part here - tinyurl.com/doxypepdraft
Deadline 11 March 2025.
Routine #HIV testing has arrived to the @nhsUHLG A&Es in #Liverpool!
Opt-out testing works, saves money, and it's finding people who would otherwise not receive a test, most often from communities who are being left behind in our progress on #HIV.
www.liverpoolecho.co...
At @science.org, the Breakthrough of the Year 2024
Lenacapavir – a new injectable drug that prevents HIV infection
"The Long Shot"
science.org/doi/10.1126/...
Private insurers labelling random people as living with HIV is appalling. Using HIV, Hepatitis C and other infections to fraud people for greater profits is absurd.
Felt this WSJ article is a bit more topical following the recent news regarding private healthcare insurers.
www.wsj.com/health/healt...
The phrase "Insurer-driven diagnoses of HIV" is something I did not expect to see.
thank you! Yaaay 🫶
Hello I am tweeting this Live on Bluesky. came from T*tter and am hoping things will be nicer here
