Manuel GonzΓ‘lez Fuente's Avatar

Manuel GonzΓ‘lez Fuente

@manuelgonzalezfuen.bsky.social

Postdoctoral researcherer at #TheUstunLab in @ruhr-uni-bochum.de working on P-bodies and bacterial pathogens. πŸ³οΈβ€πŸŒˆ he/him

222 Followers  |  309 Following  |  32 Posts  |  Joined: 12.01.2025  |  1.9525

Latest posts by manuelgonzalezfuen.bsky.social on Bluesky

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We (@manuelgonzalezfuen.bsky.social @margotraffeiner.bsky.social @shanshuo.bsky.social) had a fantastic #2025ISMPMI in Cologne with lots of amazing science and great networking meeting old friends and new ones. Hope to see you all next time in Jeju/South Korea #2027ISMPMI

18.07.2025 08:02 β€” πŸ‘ 31    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

It is depressing to be at an international conference and have everyone be like β€œwhat is going on over there”. 🫠 Not exactly making America great.

15.07.2025 07:32 β€” πŸ‘ 12    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Next in the concurrent session β€œspatial and temporal session” is @type3lab.bsky.social who will talk about their amazing findings on distinct pseudomonas subpopulations that cooperate to colonize plants #2025ISMPMI

17.07.2025 14:04 β€” πŸ‘ 10    πŸ” 5    πŸ’¬ 3    πŸ“Œ 0
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If you wanna dive into the world of #proteostasis and its role in plant immunity, visit @margotraffeiner.bsky.social poster (P-405) today. She discovered a novel proteotoxicity regulator (a protease with ubiquitin binding capacities) that plays a role in biotic and abiotic stresses! #2025ISMPMI

16.07.2025 09:34 β€” πŸ‘ 20    πŸ” 10    πŸ’¬ 0    πŸ“Œ 1

Happy to meet you at poster no. P-405 and to talk about my project at #2025ISMPMI this afternoon! 🌿

16.07.2025 09:53 β€” πŸ‘ 12    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0
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Last day of #2025ISMPMI, last poster session: dont miss @shanshuo.bsky.social fantastic poster about how we used a combination of scRNAseq and cell-type specific approaches to reveal the role of autophagy in stomatal & mesophyll immunity during Pseudomonas infection - more info ➑️ P-432 #proteostasis

17.07.2025 07:20 β€” πŸ‘ 14    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0

Hannah @mcmicrobes.bsky.social will start her own lab in 2026 (congrats a lot πŸ₯³)- watch out for some job postings in the future - she will continue to work on heat stress and the effect on leaf-microbioata! #2025ISMPMI

17.07.2025 08:51 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Sheng Yang leaves the stage for @mcmicrobes.bsky.social who continues to talk about her exciting results on how abiotic stress impacts the leaf-microbiome #2025ISMPMI

17.07.2025 08:38 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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We start the last day of #2025ISMPMI with Renier van der Hoorn who will present his pioneering work on how pathogens manipulate apoplastic defence

17.07.2025 06:17 β€” πŸ‘ 23    πŸ” 6    πŸ’¬ 2    πŸ“Œ 0
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#2025ISMPMI Manuel Gonzalez Fuente from the Üstün lab shows how pathogens like Pseudomonas target p bodies with effectors HopM1 and HopN1. ER stress induction by HopM1 counteracts p bodies.

15.07.2025 10:34 β€” πŸ‘ 8    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Enjoying the free afternoon in Cologne at #2025ISMPMI with @manuelgonzalezfuen.bsky.social @margotraffeiner.bsky.social and Christa πŸ₯‚

15.07.2025 16:03 β€” πŸ‘ 12    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Thank you very much Carmen! πŸ™

15.07.2025 13:48 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks a lot :)

15.07.2025 10:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A person presenting a scientific talk showing a slide quantifying P bodies through microscopy

A person presenting a scientific talk showing a slide quantifying P bodies through microscopy

@manuelgonzalezfuen.bsky.social explains that eukaryote P bodies contain translationally inactive RNAs.

Do pathogens induce the formation of these? Yes!

How? Effectors!… that repress ER stress response.

Why? Make plants susceptible by reducing translation of immunity genes.
#2025ISMPMI

15.07.2025 10:34 β€” πŸ‘ 23    πŸ” 10    πŸ’¬ 4    πŸ“Œ 0
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Now @manuelgonzalezfuen.bsky.social is on stage presenting his exciting project on p-bodies, and how bacteria utilize them to attenuate host translation #proteostasis #2025ISMPMI

15.07.2025 10:26 β€” πŸ‘ 17    πŸ” 6    πŸ’¬ 2    πŸ“Œ 0

It's okay, you have already seen it πŸ˜…
But we are sad that you couldn't join this year... Hope to coincide again soon!

15.07.2025 08:09 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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If you want to hear about our latest work at @suaybuestuen.bsky.social's lab on pathogen manipulation of host translation and P-bodies at #2025ISMPMI, pass by my presentation today at 12:20 in the concurrent session "Effector interference mechanism" (Room M+N).

15.07.2025 06:22 β€” πŸ‘ 13    πŸ” 7    πŸ’¬ 1    πŸ“Œ 2

Great to see @geminiteamlab.bsky.social and @bactodeath.bsky.social presenting a lot of unpublished data, new concepts and approaches in plant-microbe interactions! This should be the spirit at this meeting! Very cool plenary session at #2025ISMPMI

14.07.2025 07:58 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

@manuelgonzalezfuen.bsky.social will talk about how bacteria exploit P-bodies to attenuate host translation

@margotraffeiner.bsky.social presents a novel proteotoxicity regulator and its role in plant immunty

@shanshuo.bsky.social will emphasize the role of autophagy in stomatal immunity

13.07.2025 15:49 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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If you’re interested in the role of #proteostasis in plant immunity and how pathogens manipulate it visit our contributions at #2025ISMPMI

@manuelgonzalezfuen.bsky.social will talk on Tuesday in the effector interference session

@shanshuo.bsky.social (P-432)

@margotraffeiner.bsky.social (P-405)

13.07.2025 15:44 β€” πŸ‘ 12    πŸ” 8    πŸ’¬ 2    πŸ“Œ 0
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We made it to cologne (shortest trip to an MPMI ever πŸ˜†) looking forward to some great science! #2025ISMPMI #theustunlab

13.07.2025 12:39 β€” πŸ‘ 40    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0

Thanks a lot Sabine!
And yeah, I'm also coming to MPMI this year, so great to know we can catch up in person soon. Looking forward to it! πŸ™Œ

11.07.2025 16:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Another amazing conference ended - was great to attend two amazing sessions on #proteostasis and #condensates - with @manuelgonzalezfuen.bsky.social having a double feature and winning the Yound Scientist Award in the cell section of @sebiology.bsky.social next stop: IS- MPMI in Cologne! #2025ISMPMI

11.07.2025 11:05 β€” πŸ‘ 19    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

Thanks a lot Dan!!! And thank you for the reference letter that made it possible πŸ™

11.07.2025 10:39 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you very much! This wouldn't have been possible without your constant and valuable support and mentorship! It is definitely a shared prize!

11.07.2025 09:23 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Honoured to receive the #YoungScientistAward from the @sebiology.bsky.social in the Cell section at the Antwerp conference. Thank you for this amazing recognition β€” I’m truly grateful!

11.07.2025 08:59 β€” πŸ‘ 31    πŸ” 4    πŸ’¬ 1    πŸ“Œ 2
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Weβ€˜re ready for the #SEBconference Award Dinner 🀩 @sebiology.bsky.social @manuelgonzalezfuen.bsky.social

10.07.2025 16:40 β€” πŸ‘ 21    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Next in the condensation session is our own from @theustunlab.bsky.social @manuelgonzalezfuen.bsky.social who talks how bacteria exploit p-body condensation to suppress protein translation #proteostasis #immunity - see also our preprint www.biorxiv.org/content/10.1...

09.07.2025 14:03 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

It's happening now! @suaybuestuen.bsky.social is presenting now at @sebiology.bsky.social such an amazing work on how plants cope with proteotoxicity!! 🌱#proteostasis

09.07.2025 07:43 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
ER-Associated Nuclear Sorting Controls the Fate of Two Proteasome Activators for Intracellular Organelle Communication During Proteotoxic Stress Proteotoxic stress, characterized by the accumulation of damaged proteins, poses a significant challenge to cellular homeostasis. To mitigate proteotoxicity euk

Heading to Antwerp to attend the #SEBconference β€ͺ @sebiology.bsky.social ‬to present our latest findings (see latest version of our paper here: papers.ssrn.com/sol3/papers....) how 🌱 cope with proteotoxicity in the #proteostasis session (C1.11). Hope to see you all there!

07.07.2025 06:29 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1

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