Michael Kearse

Ad for a postdoc position in centromere biology with colorful chromosomes and centromeres made out of FIMO.

🧪 My lab has an opening for a postdoc position soon! Please share/get in touch!

We are looking for a postdoc to work on mechanisms of #RNA decay in cancer using #cryoEM with #nanobodies and #minibinders! Please RT

Found it. $7K 🤪🤪🤪

What is the publication cost?

Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.

(Please repost to reach a broad audience.)

Some things I’m very proud of from my group in no particular order: three selected talks! We work so hard on communicating our science clearly and effectively that I am especially proud of this

Hey all, I reached out to the PO of my NIGMS MIRA to ask if the gov't shut down, and rescheduling of study sections, might allow for some accommodation to the standard rule that PIs cannot resubmit a MIRA while their MIRA (or other RPG) is under review (waiting in scores or summary statements) 🧪

Image of HeLa cells expressing mCherry-Tubilin used to track various states of the cell cycle.

New work led by Madison Bandini out in @pnas.org using live cell imaging to show how HIV targets the cell cycle to double viral genomes and increase transcription. Awesome collaboration with cell cycle heroes in Suzuki lab @mcardlelab.bsky.social @uwmadison.bsky.social. www.pnas.org/doi/10.1073/...

YouTube video by RNA Collaborative Seminar Series December 10: NCI RNA Biology Initiative & Penn Institute for RNA Innovation

My talk from the latest RNA Collaborative Seminar Series is now available on YouTube. The second talk in the session was given by Rachel Braun (Sara Cherry’s lab) on TTP and its role in regulating antiviral immunity. youtu.be/2Aj-xbi3dPI #RNAsky #RNAbiology

I think some folks might be happy to see this. NIGMS MIRA R35 for EI/NI has been published. PAR-26-121 files.simpler.grants.gov/opportunitie...

Tenure Track Professorship (W1 with Tenure Track to W3) in “Molecular Biology" (f/m/d) - Heidelberg job with Universität Heidelberg | 12850668 The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a   Tenure Track Professors...

Please RT‼️ #TenureTrack position @zmbh.uni-heidelberg.de one of the best #proteostasis research centres in the world. www.nature.com/naturecareer...

Announcing the 2026 edition of the EMBO workshop on RNA localization and local translation! This meeting will be held June 30 - July 4 near Porto, Portugal. Come for exciting updates in the field from both established investigators and trainees. See the link below for details!

Anyone at Harvard need a super well-trained undergrad next semester? Cell culture, molecular bio, microscopy and data analysis. Very careful and rigorous. Good lab citizen. Ready to jump in and learn/get some data! Has light course load, so plenty of time for research! Let me know of any leads!

📢 We are pleased to announce the Molecular Mechanisms of RNA in Disease – The NCCR RNA & Disease Final Symposium Jan 26-29, 2026, in St. Moritz!
🔗 Details & updates: finalsymposium.nccr-rna-and-disease.ch
@snf-fns-ch.bsky.social @unibe.ch @ethzurich.bsky.social

#RNAsky #RNAbiology

From @kylecottrell.bsky.social lab

rnajournal.cshlp.org/content/31/1...

Registration is open for "The complex life of #RNA" 2026 @embl.org in Heidelberg!

Excellent invited speakers and 30 short talks and even more flash talks selected from the abstracts!

Thank you to our sponsors for the GA RNA Salon @rnasociety.bsky.social and Lexogen- we hosted Dr. Francesca Storici for our annual symposium yesterday @dunhamlab.bsky.social @ghaleilab.bsky.social

Dang, hard disagree. The best papers to write and read are works of art, not merely a list of data and statements.

Don’t let LLMs take this away too, for gods sake.

Conservation and evolution of the programmed ribosomal frameshift in prfB across the bacterial domain | mBio Translation termination is catalyzed by one of two release factors in bacteria, RF1 or RF2. It has been known for decades that RF2 levels in Escherichia coli are regulated by a programmed ribosomal frameshift within the prfB gene that encodes RF2. We ...

Latest from the lab! Analysis of everyone’s favorite regulatory mechanism in bacteria — the RF2 programmed frameshift! Likely present in the ancestor of bacteria, use of this mechanism is influenced by stop codon usage! Big congrats to @cassidyprints.bsky.social
journals.asm.org/doi/10.1128/...

Thank you, Eugene! Julia has worked so hard on this project.

#RNAsky #RNAbiology

An autism spectrum disorder mutation in Topoisomerase 3β causes accumulation of covalent mRNA intermediates by disrupting metal binding within the zinc finger domain Abstract. The loss and mutation of Topoisomerase 3β (TOP3B), the only known eukaryotic topoisomerase with the ability to catalyze RNA strand passage reacti

Very proud of our recently published work in @narjournal.bsky.social led by senior PhD candidate Julia Warrick. #RNA

academic.oup.com/nar/article/...

What is in the Glenclairn!?

Tonight I celebrated the week with a Manhattan. My favorite recipe lately has been:
4 oz. whiskey (tonight was Barrell Bourbon batch 36)
1 oz. of Carpano Antica Formula Sweet Vermouth (no subs)
4 dashes of Angostura
2 dashes of plum bitters
2 dashes of peach bitters

Great lab, great mentor and I love UNC Biology!

The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.

Cryo-EM structure of the naked mole-rat ribosome reveals a stabilized split 28S rRNA The naked mole-rat (Heterocephalus glaber) is a long-lived mammal with remarkable resistance to cancer and hypoxia, suggesting the evolution of robust proteostasis networks. The ribosome, the central ...

We have a new preprint for you. Naked mole rats are very long-lived rodents and have increased translational fidelity.

Interestingly, 28S ribosomal RNA is split. Here we investigated the structure of the ribosome by single particle cryo-EM. Take a look.
www.biorxiv.org/content/10.1...

Want to do a PhD in biology? Our projects for 2026 are now live! If you're considering a PhD, or know someone who is, we have projects that span the biosciences to serve as inspiration.

Reach out to our academics to discuss these or more options if you have an idea of your own 👇
bit.ly/dphilbio25

From MBoC: Timothy J. Stasevich, Colorado State University, developed All Probes Plasmids (APPs) to simplify single-mRNA translation imaging—just 2 plasmids for multicolor, long-term tracking. www.molbiolcell.org/doi/10.1091/... #CellBiology