Wenfei Xian (冼文飞)'s Avatar

Wenfei Xian (冼文飞)

@wenfeixian.bsky.social

PhD student in Weigel world https://www.weigelworld.org/ how genetic variants are generated, how they evolve, and how they are maintained in the genomes. github: https://github.com/Wenfei-Xian

103 Followers  |  156 Following  |  7 Posts  |  Joined: 11.01.2024  |  1.7671

Latest posts by wenfeixian.bsky.social on Bluesky

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1/3 New preprint led by Shanshan Wang, in collaboration with the Timmermans lab.

Several groups have presented sc/snRNA-seq analyses of Arabidopsis leaves after bacterial infection before. Is there anything left to discover? Turns out: Yes.

#plantscience
www.biorxiv.org/content/10.1...

02.08.2025 14:46 — 👍 73    🔁 39    💬 2    📌 1

😃

07.08.2025 07:35 — 👍 2    🔁 0    💬 0    📌 0
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Super happy to share that I’ve passed my PhD defense! 🍾
It’s been an amazing journey doing my PhD in the Weigel World.
Huge thanks to my supervisor, Detlef @plantevolution.bsky.social , even with your crazy schedule, you always made time to guide me.
Couldn’t have done it without all your support!!!

06.08.2025 13:36 — 👍 26    🔁 2    💬 4    📌 0
Diagram of somatic TE insertions across the A. thaliana genome

Diagram of somatic TE insertions across the A. thaliana genome

In our latest @biorxiv-genomic.bsky.social preprint, we describe our approach to use PacBio HiFi reads to detect somatic TE transposition -- good enough to detect rare events that are present in only single cells. Led by Andrea Movilli.
#plantscience
www.biorxiv.org/content/10.1...

10.02.2025 10:57 — 👍 77    🔁 38    💬 4    📌 3

Thanks, Eirik 😊

16.01.2025 15:38 — 👍 0    🔁 0    💬 0    📌 0

Large repeats are common in plant organellar genomes. Half of the A. thaliana mitogenomes we assembled have two large repeat pairs, while others have only one, where we identified two potential HGT events. Large repeats link to geography and cold traits.
Feedback welcome on bioRxiv, Email, etc.!

15.01.2025 09:57 — 👍 15    🔁 7    💬 1    📌 0
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Announcing a curated collection of long-read genomes for Arabidopsis thaliana: The 1001 Genomes Plus Project. Currently 453 unique accessions/almost 600 assemblies.
Interested in contributing? Please contact us!
#plantscience
www.biorxiv.org/content/10.1...

27.12.2024 07:51 — 👍 128    🔁 91    💬 2    📌 0
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Phosphorylation‐dependent activation of the bHLH transcription factor ICE1/SCRM promotes polarization of the Arabidopsis zygote In Arabidopsis thaliana, the asymmetric cell division (ACD) of the zygote gives rise to the embryo proper and an extraembryonic suspensor, respectively. This process is controlled by the ERECTA-YODA...

Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉

Want to discover the exciting new functions of ICE1/SCRM?

Want to dive into the latest model of plant embryo initiation?

Don’t miss out—check it out here:
nph.onlinelibrary.wiley.com/doi/10.1111/...

17.11.2024 19:45 — 👍 15    🔁 6    💬 5    📌 0
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Accessory proteins increase the efficiency of RNA editing by Arabidopsis chloroplast editosomes https://www.biorxiv.org/content/10.1101/2024.04.05.588343v1 RNA editing modifies cytidines to uridines in plant organelle transcripts so that their sequence dif

Accessory proteins increase the efficiency of RNA editing by Arabidopsis chloroplast editosomes https://www.biorxiv.org/content/10.1101/2024.04.05.588343v1

07.04.2024 05:19 — 👍 1    🔁 1    💬 0    📌 0
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Effects of spontaneous mutations on survival and reproduction of Drosophila serrata infected with Drosophila C virus https://www.biorxiv.org/content/10.1101/2024.04.04.588202v1 The impact of selection on host immune function genes has been widely documented. However, it remain

Effects of spontaneous mutations on survival and reproduction of Drosophila serrata infected with Drosophila C virus https://www.biorxiv.org/content/10.1101/2024.04.04.588202v1

07.04.2024 05:32 — 👍 0    🔁 1    💬 0    📌 0

How cool is that -- would not have guessed that the type of genetic incompatibility, hybrid necrosis, that we've studied for many years, is also the cause for graft incompatibility. I wonder whether it's a story of mismatched helper NLRs... @kamounlab.bsky.social

04.04.2024 15:43 — 👍 16    🔁 5    💬 2    📌 0
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Transposable elements as evolutionary driving force to ecological speciation in cactophilic Drosophila species https://www.biorxiv.org/content/10.1101/2024.03.27.587021v1 Background The host shift in insects has been considered a key process with potential to collaborate

Transposable elements as evolutionary driving force to ecological speciation in cactophilic Drosophila species https://www.biorxiv.org/content/10.1101/2024.03.27.587021v1

30.03.2024 20:32 — 👍 2    🔁 2    💬 0    📌 1
A view of the Milky Way supermassive black hole Sagittarius A* in polarized light.

A view of the Milky Way supermassive black hole Sagittarius A* in polarized light.

The Event Horizon Telescope has measured the *polarized* radiation from our friendly neighborhood black hole, Sgr A*! Press release: eventhorizontelescope.org/blog/astrono..., papers in next skeet 🔭🧪

27.03.2024 13:10 — 👍 102    🔁 47    💬 5    📌 6
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Disparity of cycad leaves dispels the living fossil metaphor - Communications Biology An analysis of leaf disparity through time in cycads shows that this group has a dynamic and expanding morphological diversity until the present, and thus does not fit the ‘living fossil’ hypothesis o...

last week my latest paper on #cycads came out.
The article deals with the idea of cycads as "living #fossils", but what does this mean exactly, and what did we actually test? A thread for #FossilFriday!
www.nature.com/articles/s42...

22.03.2024 14:08 — 👍 31    🔁 24    💬 1    📌 0
A spiral galaxy takes up almost the entire frame, from bottom left to top right. The circular-shaped galaxy is not seen perfectly face-on, but is slightly tilted. The galaxy has a bright light yellow central core that is surrounded by tightly wound spiral arms that are oriented counter clockwise. Beginning at the core and going to the right and then to the top are prominent, dark brown dust lanes. The other region forms an arc toward the bottom left, starting near the core at around 9 o’clock. The outer edges of the galaxy are where there are brighter blue areas filled with clusters of stars. Pink star clusters are found throughout, are most obvious toward the edges, and appear more clustered toward the middle-right edge and toward the bottom left corner. The background of space is black.

A spiral galaxy takes up almost the entire frame, from bottom left to top right. The circular-shaped galaxy is not seen perfectly face-on, but is slightly tilted. The galaxy has a bright light yellow central core that is surrounded by tightly wound spiral arms that are oriented counter clockwise. Beginning at the core and going to the right and then to the top are prominent, dark brown dust lanes. The other region forms an arc toward the bottom left, starting near the core at around 9 o’clock. The outer edges of the galaxy are where there are brighter blue areas filled with clusters of stars. Pink star clusters are found throughout, are most obvious toward the edges, and appear more clustered toward the middle-right edge and toward the bottom left corner. The background of space is black.

Asymmetry has never been so pleasing! Hubble’s near-infrared and visible-light view shows jostled dark brown dust lanes and a core knocked off center. Why? Galaxy M96 is part of a group of galaxies in a gravitational “tug of war.”

Credit: ESA/Hubble, NASA, and the LEGUS Team. 🔭 🧪

22.03.2024 14:55 — 👍 39    🔁 13    💬 1    📌 1
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Permutation analysis prior to variable selection greatly enhances robustness of OPLS analysis in small cohorts https://www.biorxiv.org/content/10.1101/2024.03.18.585475v1 The R-workflow roplspvs (R orthogonal projections of latent structures with permutation over variabl

Permutation analysis prior to variable selection greatly enhances robustness of OPLS analysis in small cohorts https://www.biorxiv.org/content/10.1101/2024.03.18.585475v1

20.03.2024 18:49 — 👍 0    🔁 1    💬 0    📌 0

reposting to 🧪 cause it's a very cool paper

16.03.2024 15:53 — 👍 26    🔁 5    💬 1    📌 0
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IDRWalker: A Random Walk based Modeling Tool for Disordered Regions in Proteins https://www.biorxiv.org/content/10.1101/2024.03.17.585378v1 Motivation: With the advancement of structural biology techniques, the elucidation of increasingly l

IDRWalker: A Random Walk based Modeling Tool for Disordered Regions in Proteins https://www.biorxiv.org/content/10.1101/2024.03.17.585378v1

19.03.2024 02:47 — 👍 0    🔁 1    💬 0    📌 0
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Estimation of spatial demographic maps from polymorphism data using a neural network https://www.biorxiv.org/content/10.1101/2024.03.15.585300v1 A fundamental goal in population genetics is to understand how variation is arrayed over natural lan

Estimation of spatial demographic maps from polymorphism data using a neural network https://www.biorxiv.org/content/10.1101/2024.03.15.585300v1

18.03.2024 05:32 — 👍 2    🔁 4    💬 0    📌 0

T2T with ONT-only 🏃🏻🍅🌽

17.03.2024 17:21 — 👍 1    🔁 1    💬 0    📌 0
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Characterising tandem repeat complexities across long-read sequencing platforms with TREAT https://www.biorxiv.org/content/10.1101/2024.03.15.585288v1 Tandem repeats (TR) play important roles in genomic variation and disease risk in humans. Long-read

Characterising tandem repeat complexities across long-read sequencing platforms with TREAT https://www.biorxiv.org/content/10.1101/2024.03.15.585288v1

17.03.2024 17:47 — 👍 0    🔁 1    💬 0    📌 0
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German-Spanish-Argentinean collaboration on haplotype-resolved Malbec 🍇🍷genome. Trio-binning used short reads from the parental varietals Prunelard and Magdeleine Noire des Charentes, which are both almost extinct

academic.oup.com/hr/advance-a...

16.03.2024 11:58 — 👍 7    🔁 3    💬 0    📌 0
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Global climate change effect on Asian Mus musculus; Implication from last glacial maximum to the end of the 21st century https://www.biorxiv.org/content/10.1101/2024.03.14.584992v1 Global climate change poses unprecedented challenges to biodiversity, prompting urgent investigation

Global climate change effect on Asian Mus musculus; Implication from last glacial maximum to the end of the 21st century https://www.biorxiv.org/content/10.1101/2024.03.14.584992v1

16.03.2024 14:32 — 👍 0    🔁 2    💬 0    📌 0
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FST and genetic diversity in an island model with background selection https://www.biorxiv.org/content/10.1101/2024.03.15.585154v1 Background selection, by which selection on deleterious alleles reduces diversity at linked neutral

FST and genetic diversity in an island model with background selection https://www.biorxiv.org/content/10.1101/2024.03.15.585154v1

16.03.2024 14:33 — 👍 2    🔁 2    💬 0    📌 0
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Genome streamlining: effect of mutation rate and population size on genome size reduction https://www.biorxiv.org/content/10.1101/2024.03.14.584996v1 Genome streamlining, i.e. genome size reduction, is observed in bacteria with very different life tr

Genome streamlining: effect of mutation rate and population size on genome size reduction https://www.biorxiv.org/content/10.1101/2024.03.14.584996v1

15.03.2024 08:33 — 👍 2    🔁 3    💬 0    📌 0
Jupiter Rotation using the Hubble Space Telescope - 2024
The Hubble Space Telescope images used in this animated science visualization present a full rotation of the giant planet Jupiter. This is not a real-time mo... Jupiter Rotation using the Hubble Space Telescope - 2024

The #Hubble images used in this animated science visualization present a full rotation of #Jupiter. It's not a real-time movie, but snapshots of the planet, taken in January, have been photo-mapped onto a sphere, and the model is then rotated in animation. 🔭 🧪

14.03.2024 16:28 — 👍 17    🔁 10    💬 0    📌 0
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Why you should publish your posters Publishing your poster in a DOI repository like Zenodo extends the lifespan of your poster beyond the conference, reaching audiences who…

#Fungal24 gone the sorry way of Gordon Conference with overly restrictive policy on social media, posters etc. pretty bad given the conference is way oversubscribed.

ECRs, why don’t you publish your posters instead? kamounlab.medium.com/why-you-shou...

13.03.2024 16:19 — 👍 0    🔁 2    💬 0    📌 0
Gaby Moreno - "Quizás, Quizás, Quizás" | LIVE at The Kennedy Center
Gaby Moreno performs "Quizás, Quizás, Quizás" LIVE at the Kennedy Center.Watch the full concert: https://www.youtube.com/watch?v=qkBexC-n0DsSubscribe to The ... Gaby Moreno - "Quizás, Quizás, Quizás" | LIVE at The Kennedy Center

Quizás, Quizás, Quizás #EffectorWisdom youtu.be/CmLNM6WHUHc?...

12.03.2024 03:25 — 👍 1    🔁 1    💬 0    📌 -1
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

New study gives support to the “RNA World” hypothesis. An RNA has been synthesized that can replicate other RNA, showing an in-principle mechanism for how it could have worked.

#evobio 🦫🦋 🗃️🧠 🌱🐋🧪🌎

09.03.2024 23:48 — 👍 80    🔁 31    💬 1    📌 2
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Recommendations for accelerating open preprint peer review to improve the culture of science As preprints become more widely used and accepted, they raise the possibility of rethinking the peer-review process. This Consensus View issues a call to action to accelerate the growing momentum of p...

For funders, departments, and institutions: Consider preprints and their reviews in evaluations for funding, hiring, degree requirements, fellowship eligibility, tenure, and promotion. #preprintreview journals.plos.org/plosbiology/...

08.03.2024 16:30 — 👍 8    🔁 8    💬 0    📌 0

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