Florian Ingelfinger

ZEB2 is a master switch controlling the tumor-associated macrophage program Sheban et al. present a single-cell CRISPR screen to dissect macrophage gene regulation in a pan-cancer tumor-associated macrophage (TAM) atlas. Using a generative model, they identify ZEB2 as a key d...

We are excited to share our new study @cp-cancercell.bsky.social identifying Zeb2 as a master genetic switch controlling the tumor-associated macrophage (TAM) program. Led by Fadi Sheban, Truong San Phan, Kai Kun Xie & @florianingelfinger.bsky.social. (1/20)
www.cell.com/cancer-cell/...

10.04.2025 19:04 — 👍 17    🔁 5    💬 1    📌 1

Towards the Next Generation of Data‐Driven Therapeutics Using Spatially Resolved Single‐Cell Technologies and Generative AI This review explores the technical advances in single-cell multi-omics technologies alongside the parallel development of generative AI tools to uncover biological insights. By integrating these inno...

Are you an immunologist interested in spatially-resolved single cell technologies and generative modeling but dont know where to start?

Check out our recent EJI review with Avital Rodov, Hosna Baniadam, Robert Zeiser, @idoamitlab.bsky.social, Nir Yosef & Tobias Wertheimer!

20.02.2025 17:20 — 👍 9    🔁 3    💬 0    📌 0

Postdoctoral fellow - Saez-Rodriguez Group Your group Saez-Rodriguez Research Group Your supervisor Julio Saez-Rodriguez Your role As a postdoctoral fellow in the Saez Rodriguez group, you will develop and apply computational methods and tools...

Post-doc opening to join our lab @ebi.embl.org to develop&apply #bioinformatics and #machine-learning methods to study intra-/extra cellular networks to extract disease mechanisms from #single-cell and #spatial multiomic data - please share 🙏 : embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

11.02.2025 10:17 — 👍 57    🔁 46    💬 0    📌 1

Graphical abstract of BioChatter

Applying LLMs to biomedical research today can go one of two ways: we either use a closed-source web app, or we get coding ourselves. Many researchers lack training for the latter, so their only choice is the former. We want to change that. www.nature.com/articles/s41...

05.02.2025 09:15 — 👍 78    🔁 37    💬 2    📌 2

Big congrats, thomas, tobi, roman and team!! 🔥🔥

31.01.2025 07:49 — 👍 0    🔁 0    💬 0    📌 0

Impossible to stay on the dark aide under these circumstances… talk to you soon @rsankowski.bsky.social :)

22.01.2025 18:02 — 👍 1    🔁 0    💬 0    📌 0