Juliane Glaser

Join us for tomorrow´s 📢 CIBSS Seminar Series

🗓 09 Dec 2025 | 12:00–13:00
👩‍🔬 @julianeg.bsky.social, (@mpi-ie.bsky.social)
🎙 Endogenous retroviruses and mouse developmental malformations
📍 Lecture Hall, Institute of Biology I, Hauptstr. 1

See more: kurzlinks.de/iplv

#CIBSS #Science #Immunobiology

Specialized signaling centers direct cell fate and spatial organization in a mesodermal organoid model Stem cell–derived mesodermal organoids reveal how signaling centers guide cell fate and tissue organization.

🎉 Our deconstructed, stem-cell–based approach to studying signaling centers and limb-development cell types is out! 🥳 So nice to see it in its final form after the preprint— and huge thanks to the community for all the enthusiasm and interest since then!
www.science.org/doi/10.1126/...

Congratulations Can & team!!! Happy to see it out and looking forward to reading the peer-reviewed version 😊

Project Assistant The Department of Medical and Translational Biology at the Faculty of Medicine is now seeking a project assistant for a research project related to human brain aging. The position is full-time and lim

📣We are looking for a Project Assistant to join my group at the Wallenberg Center for Molecular Medicine at Umeå University. Join us if you are interested in transposable elements, epigenetics and human brain aging. 🧠🧬 Dont hesitate to reach out with any questions! 📣
umu.varbi.com/en/what:job/...

Development's Pathway to Independence Programme Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...

Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:

Mentoring
Profile raising
Leadership training
Network building

Spread the word...

www.biologists.com/grants/devel...

Congratulations Fany!! 🥂

Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀

Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function

now revised and journal accepted at www.science.org/doi/10.1126/...

🧵👇

Join @mpercharde.bsky.social Lab at the MRC LMS! We have an 18mo postdoc position to cover a couple of projects (maternity leave and paper revisions). The projects are focussed on chromatin in early mouse embryos and metabolism in mouse embryonic stem cells and pluripotency.

Postdoctoral Researcher in "Cancer Neuroscience: the impact of neural activity on 3D genome organization and cellular plasticity in glioblastoma”

Excited to share I’ve received a #SSMF #Consolidator grant!

📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics

🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM

Interested? Apply now 👇
rb.gy/m7xz7b

Thrilled to share our new review in Current Opinion in Genetics & Development on TE driven innovation in gene regulation🤘. I am honored to be part of this with two major TE aficionados @cedricfeschotte.bsky.social and @trono-lab.bsky.social
#TEsky #TEworldwide

authors.elsevier.com/c/1m6MC,LqAZ...

Cadherins modulate the self-organizing potential of pseudo-embryos Gastruloids derived from ES cells mimic embryonic patterning through robust self-organization. Mayran et al. uncover that this competence depends on a cadherin switch regulated by Snai1-driven E-cadhe...

Happy to present the final version of our Cadherin and gastruloid manuscript, online at @cp-cellreports.bsky.social.
www.cell.com/cell-reports...
Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12

🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨

#PhD #3DGenome

piRNA-directed DNA methylation may not be a mammalian invention, but can already be found in the germline of axolotl salamanders
Donal O’Carroll and coworkers
www.embopress.org/doi/full/10....

Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice - Nature Communications KRAB-zinc finger proteins repress retrotransposons and rapidly evolve in mammals. Here, the authors show that ERV insertions drive the emergence and diversification of new KZFP genes in mice, revealin...

Having a lot of fun at #EMBOMobileGenome 😃
Perfect timing for our paper from the lab of @toddmacfarlan.bsky.social to be out @natcomms.nature.com!!

…and I’m currently on the job market looking for a new scientific home!

www.nature.com/articles/s41...

Programme of the upcoming TriRhena Gene Regulation Club in Basel on November 5, 2025 https://www.ie-freiburg.mpg.de/gene-regulation-club

Here is the schedule for the next TriRhena Gene Regulation Club at the FMI @fmiscience.bsky.social in Basel 🇨🇭 next week (5 Nov 2025; 14:00-18:45).

Exciting topics ahead & we are looking forward to the #newPI talks by @julianeg.bsky.social (MPI) & Anupama Hemalatha (FMI).

www.ie-freiburg.mpg.de/grc

Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!

🌟Im happy to share that this winter I'll be starting my lab at the Wallenberg Center for Molecular Medicine at Umeå University! Excited to join the Department of Medical and Translational Biology as a Wallenberg Fellow and looking forward to new collaborations and cool transposon research 🤩 🧬

Cracking the code of the non-coding genome via allele-specific genomics?
Can we link non-coding elements—like lncRNAs and enhancers—to their protein-coding target genes, and in doing so, connect overlapping non-coding disease variants to their protein-coding counterparts?

I am absolutely delighted to share the invited speakers for our upcoming @bsdb.bsky.social "Molecules to Morphogenesis" meeting!

Registration and abstract submission is now open - join us!

bsdb.org/meetings/

March 23-26, 2026 - UK

I am very excited to announce the opening of the submission site for the upcoming Conférences Jacques Monod on Developmental Biology, May 18-22, 2026 cjm.sb-roscoff.fr/en/conferenc...
@lionlchristiaen.bsky.social and I have an exciting program of speakers and slots for selected short talks, etc.

Developmental Biology and Disability - the Node Hopeful monsters. Morphospace. Mutation. Natural variation. Mutagenesis screens. Polymorphism. Deformity. Phenotype. Disease. Adaptation. Anomaly.

“Developmental biology is fundamentally beautiful. We are no less beautiful for our variation. Instead, perhaps we are more so. Perhaps we are remarkable. Perhaps we are full of wonder.”

Read this insightful post by Bethan on the Node.

thenode.biologists.com/developmenta...

#Disability

🔬 Limb regeneration depends on regenerative signaling center cells — but how do these cells influence others to proliferate, migrate, or differentiate?
We’re recruiting PhD or Postdoc candidates to explore this with our collaborator @osvaldo-chara.bsky.social !

Our publication is out today!Big Thanks go to my amazing collaborators: @sedonamurphy.bsky.social for her imaging brilliance and @mattjones.bsky.social for his computational support.They both saw the potential in this project and helped me to explore what turned out to be an exciting discovery.

In our "Meet the First Author" series, we spoke with Magdalena Schindler and Christian Feregrino about the fascinating world of bats, how teamwork can lead to friendship, and the potential of basic research. Watch the video ⬇️ and read the full interview here: www.molgen.mpg.de/2025-16-10-m...

Out now! 🎉 Check the thread & preprint to see why we think E–P specificity is real in mammals — and, well, a few other interesting things popped up too 👀
Huge thanks to @danielibrahim.bsky.social, @arnaudkr.bsky.social & @stemundi.bsky.social and fantastic people in their labs — what a journey! 🧪🔬

Did transposable elements shape brain evolution — and if so, which ones, and in which cell states and lineages? Led by @tyamadat.bsky.social, we explored this question in cerebellum development using sequence-based deep learning models!
www.biorxiv.org/content/10.1...

@blanka-majchrzycka.bsky.social did an absolutely amazing job!! created everything from scratch, set up #RMCE with the fantastic help from @arnaudkr.bsky.social and saw this thing through.
She'll be looking for a #postdoc position very soon. I'd ask her if I were you!!!

Promoter-proximal gatekeepers restrict pleiotropic enhancer inputs to achieve tissue specificity Developmental enhancers are central regulatory elements that can activate multiple genes, yet how they selectively regulate one gene over its neighbours remains unclear. Using the Drosophila twist E3 ...

Ever wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one?

Check our latest preprint, led by @mmasoura.bsky.social, to find out!
www.biorxiv.org/content/10.1...

Promoter-proximal gatekeepers restrict pleiotropic enhancer inputs to achieve tissue specificity Developmental enhancers are central regulatory elements that can activate multiple genes, yet how they selectively regulate one gene over its neighbours remains unclear. Using the Drosophila twist E3 ...

you must check out @yghavi.bsky.social and @mmasoura.bsky.social's story, who found a similar mechanism in Drosophila. it's so cool if two works align!!

www.biorxiv.org/content/10.1...

What mediates enhancer-promoter compatibility? Get some answers & learn about the important of the promoter-proximal
region here 👇
Congratulations @blanka-majchrzycka.bsky.social @danielibrahim.bsky.social on this beautiful work!!!!🥂🥂