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IBC2

@ibc2-gu.bsky.social

This is the Institute of Biochemistry II at Goethe University Frankfurt, Germany. Our research focuses on cellular #signaling, #ubiquitin, #autophagy, #pexophagy, #ER-phagy, #TPD, #degraders, #molecularglues, #proteomics, #CRISPR, #cancer, #infection.

121 Followers  |  116 Following  |  6 Posts  |  Joined: 28.11.2024  |  1.6782

Latest posts by ibc2-gu.bsky.social on Bluesky

So proud of this work by #rukmini mukherjee on intersection of Cell Biology and Microbiology

12.06.2025 19:34 โ€” ๐Ÿ‘ 29    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Phosphoribosyl ubiquitination of SNARE proteins regulates autophagy during Legionella infection | The EMBO Journal imageimageAmong the hundreds of proteins that are secreted by Legionella pneumophila (the causative agent of Legionnairesโ€™ disease) during infection, the SidE class of effectors modify host proteins b...

Check out our latest paper: #Legionella SidE effectors phosphoribosyl-ubiquitinate SNAREs STX17 & SNAP29, stalling #autophagy and fueling bacterial growth. Dive into how pathogens hijack #ubiquitin driven autophagy @embojournal.org @ibc2-gu.bsky.social @idikic.bsky.social doi.org/10.1038/s443...

18.06.2025 07:47 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@andreashorchler.bsky.social @timongremmels.bsky.social
@hartungingo.bsky.social
@idikic.bsky.social
@goetheuni.bsky.social @unimainz.bsky.social
& many more ...
Video Credit: Filmwerker

23.04.2025 18:11 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿš€ An inspiring milestone worth sharing! ๐ŸŽฅ
Yesterday marked the official kick-off event for the 2nd phase of our BMBF-funded #Cluster4Future @proxidrugs.bsky.social. Thanks to all scientists, stakeholders, citizens & schools for actively participating and making it a very special day for us!

23.04.2025 18:11 โ€” ๐Ÿ‘ 5    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Congratulations @adricovapinto.bsky.social ๐ŸŽ‰

28.03.2025 09:05 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Getting ready for day 3 of #FCQC2025! Excited to learn what is new in the fields of โ€œProteinopathies & neurodegenerationโ€ and โ€œEmerging therapeuticsโ€.

@enablefrankfurt.bsky.social @ibc2-gu.bsky.social @proxidrugs.bsky.social

26.03.2025 07:36 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿคฉ 2nd day of #FCQC2025 conference in Frankfurt was filled with inspiring lectures, vibrant discussions, great posters and a lot of joy of meeting colleagues from all over the world! A huge thanks to all organizers & supporters!
@goetheuni.bsky.social @sfb1177.bsky.social @proxidrugs.bsky.social

26.03.2025 08:23 โ€” ๐Ÿ‘ 14    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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After an inspiring first day, weโ€™re excited to dive into the second day of #FCQC2025 filled with amazing talks on โ€žOrganelles in biology and diseaseโ€œ and โ€žRNA and protein quality controlโ€œ.

@enablefrankfurt.bsky.social @proxidrugs.bsky.social @ibc2-gu.bsky.social @dfg.de

25.03.2025 09:30 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Great kick off of our #FCQC2025! Looking forward to the next days full of inspiring sessions, meaningful conversations, and exciting new connections ๐Ÿ™Œ

@sfb1177.bsky.social @enablefrankfurt.bsky.social @proxidrugs.bsky.social @goetheuni.bsky.social

24.03.2025 17:10 โ€” ๐Ÿ‘ 8    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

What a timing! We just heard about this amazing story a moment ago at the #FCQC2025, and we can already dig further and read the paper! ๐Ÿ˜ Congratulations, Leo and team! #ubiquitin #proteasome

24.03.2025 15:50 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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๐Ÿšจ Save the date! ๐Ÿšจ
We're thrilled to announce our International Symposium on Cell & Structural Biology of Host-Pathogen Interaction
๐Ÿ“… Sept 10-12, 2025
๐Ÿ“
@cssbhamburg.bsky.social Hamburg

Registration starts soon
For more info:
humansandmicrobes2025.de

29.01.2025 13:21 โ€” ๐Ÿ‘ 7    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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We are pleased to introduce the 4th Frankfurt Conference on Quality Control in Life Processes organized by
@idikic.bsky.social, Maike Windbergs & Volker Dรถtsch. The program is now availableโ€”more updates to come.
fcqc.de
@proxidrugs.bsky.social @enablefrankfurt.bsky.social #FCQC2025 #autophagy

29.01.2025 10:32 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
Engineering and sculpturing a smaller easy-to-use CRBN for new drug discoveries

Engineering and sculpturing a smaller easy-to-use CRBN for new drug discoveries

โ€˜Easy to handleโ€™ Cereblon โ€“ a new tool for drug discovery and molecular glue screening ๐Ÿ‘

www.sciencedirect.com/science/arti...

Congrats to the ฤikiฤ‡ lab and Merck KGaA, in collaboration with Enamine Ltd, the Nowak Lab, the Langer Lab and iBET ๐Ÿ˜€
#CRBN #TPD #PROTAC

28.11.2024 07:31 โ€” ๐Ÿ‘ 32    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

An impressive display of technologies was used to discover how cryptic #splicing causes #celldeath and leads to development of human #diseases.
www.science.org/doi/10.1126/...
It was a real joy to work together with @prieto-garcia.bsky.social and all other collaborators. Many thx ๐Ÿ‘๐Ÿ˜€

17.11.2024 22:41 โ€” ๐Ÿ‘ 30    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Happy to join Bluesky! Please connect
@idikic.bsky.social @manuelkaulich.bsky.social @prieto-garcia.bsky.social @hartungingo.bsky.social@diefenbacherlab.bsky.social

28.11.2024 09:49 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@ibc2-gu is following 20 prominent accounts