Dr Darrell H S Tan, MD PhD FRCPC

Proud to announce on World AIDS Day today that our 2025 update to Canadian guideline on HIV PrEP and PEP is now published in @cmaj.ca! The guideline include 31 recommendations and 10 good practice statements to support clinical decision making.

Learn more 👉 doi.org/10.1503/cmaj...

Fresh from the podium at EACS 2025 in Paris: Doxycycline PEP was associated with a sustained positive impact on syphilis and chlamydia incidence but also increases in gonorrhea AMR in the open label extension of the DoxyVAC trial among GBM in France.

You’re Not Imagining It. Health Misinformation Is Everywhere | The Walrus And yes, some of it has probably gotten to you

Looking forward to presenting the keynote "The Health Misinformation Crisis!" at #WTC2025!

Warm up with my (current) Top 10 misinformation concerns: thewalrus.ca/before-you-s... via @thewalrus.ca

#GoScience!

IAS welcomes US bipartisan move to protect PEPFAR 16 July 2025 (Kig

The IAS welcomes the bipartisan move in the US Senate to protect the President’s Emergency Plan for AIDS Relief (#PEPFAR) from the proposed USD 400 million cuts in President Trump’s rescission package.

📢 Read our full statement now & join our call to safeguard essential #HIV services!

Dr Cissy Kityo highlighted the role of long-acting drugs for treating HIV in LMICs in this morning’s excellent plenary at #IAS2025, buoyed by yesterday’s announcement of the Viiv/MPP updated voluntary licensing agreement for CAB and updated WHO guidelines supporting CAB/RPV as a treatment option.

Mitchell Warren of AVAC shares data, based on many assumptions, of potential injectable PrEP use in 2026 based on 2024 oral uptake & preference data.
And the ways forward.....prioritise, prioritise, prioritise (sorry, I changed the spelling 😘)
#IAS2025

YouTube video by CAHRACRV CAHR 2025: Clinical Sciences Plenary Session

Grateful to have been asked to deliver the clinical sciences plenary talk at #cahr2025 a couple weeks ago about 'The Promise of PrEP'!
www.youtube.com/watch?v=0xuF...

Important study on the limited value of using HIV RNA versus traditional Ag/Ab tests to screen for HIV among people using PrEP.

Sustained Effectiveness of Doxycycline Post-Exposure-Prophylaxis in a Large Sexual Health Clinic over 96 Weeks: An Interrupted Time Series Analysis Sexually transmitted infections remain prevalent in the U.S. This controlled interrupted time series study evaluated the impact of doxycycline post-exposure prophylaxis (doxy-PEP) among 4,592 PrEP users.

Sustained Effectiveness of Doxycycline Post-Exposure-Prophylaxis in a Large Sexual Health Clinic over 96 Weeks: An Interrupted Time Series Analysis

✅ Just Accepted
#IDSky

Call for Applications for IDSA Journals 2025 Editorial Mentoring Program The IDSA journals’ editorial mentoring program connects junior infectious diseases faculty (instructors and assistant professors) with journal editors for mentorship and training in the day-to-day work of a medical journal editor.

The IDSA Journals Editorial Mentoring Program offers junior ID faculty hands-on experience in journal editing.

Mentees will work closely with editors, review manuscripts, and attend IDWeek 2025. Stipend & travel support are included.

Learn More ⤵️

Trump Administration Ends Program Critical to Search for an H.I.V. Vaccine

Breaking News: The Trump administration has dealt a sharp blow to work on HIV vaccines, terminating a $258 million program critical to the research.

Be part of Canada’s largest survey of 2S/LGBTQIA+ people!

Help improve access to new HIV treatments!

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sexnowsurvey.com

A recent paper from my team highlighted by HIV Medicine.

....I think your preferences make sense and are evidence-based! But people's values and preferences differ, and factors like cost and feasibility are also important. GRADE asks panels to consider it all, and to explain their thinking transparently. We wanted to promote 'PrEP choice' - stay tuned!

Great feedback @benoitlemire.bsky.social! Some things evolved since the Sep 2024 version - for instance, the updated recommendations are indeed framed in terms of behaviour not identity. The slightly wordy classifications come from GRADE (www.gradeworkinggroup.org). As for preferred regimens...

Honoured to have been asked by Dalhousie’s Division of Infectious Diseases to give the TJ Marrie lecture on “Mpox then and now: lessons learned from a re-emerging infectious disease” at the 2025 Research Day recently! Plus, inspiring presentations from students and the Cdn Centre for Vaccinology.