Mohamed Ali, PhD's Avatar

Mohamed Ali, PhD

@mohamed-al.bsky.social

Structural Biologist | Accelerating drug discovery Obsessed with X ray-Crystallography and Cryo-EM Sharing: Practical Structural Bio Tips

86 Followers  |  235 Following  |  10 Posts  |  Joined: 16.02.2025  |  1.5395

Latest posts by mohamed-al.bsky.social on Bluesky

I have data collection in two days.
Thanks for wishing me luck.

03.03.2025 00:39 — 👍 2    🔁 0    💬 0    📌 0
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A beautiful protein crystal next to several salt crystals.

#crystallography #structuralbiology #crystal

02.03.2025 18:55 — 👍 1    🔁 0    💬 1    📌 0
Join us > Malene R. Jensen @ IBS Grenoble If you are interested in joining our team, please send CV and letter of motivation to Malene Ringkjøbing Jensen. We always welcome applications from master students, Ph.D. students and postdoctoral fe...

A postdoctoral position at the Institute for Structural Biology

Using X-ray crystallography, Cryo-EM and NMR to study the structural assembly of MAPK signalling pathway complexes.

Link for details

www.jensen-nmr.fr?page_id=59

26.02.2025 12:30 — 👍 1    🔁 1    💬 0    📌 0
https://iit.taleo.net/careersection/ex/jobdetail.ftl?lang=it&job=25000017

🚨 Postdoctoral opportunity 🚨

An exciting postdoctoral position in RNA-directed drug discovery.

Check the link for more information.

#RNASynthesis #DrugDiscovery #RNABiochemistry #StructurallBiology

t.co/VgkZD7dPsT

26.02.2025 05:44 — 👍 0    🔁 0    💬 0    📌 0
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George Sheldrick (1942-2025): A Crystallographic Pioneer

In 2010, a single paper of George Sheldrick sent Acta Crystallographica A’s impact factor soaring from 2.05 to 54—surpassing Science and Nature. A true testament to his influence.

#Crystallography #SHELX #ScienceLegend

24.02.2025 23:07 — 👍 4    🔁 1    💬 0    📌 0
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George Sheldrick (1942-2025): A Crystallographic Pioneer

The world of crystallography has lost a legend. George Sheldrick’s #SHELX programs for structure determination, enabling countless discoveries.

#Crystallography #StructuralBiology #SHELX #ScienceLegend

24.02.2025 23:07 — 👍 2    🔁 0    💬 0    📌 0
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Nature’s Crystallization Experiment

As I looked out the window, I saw an ice sculpture, crafted by snow, wind, and temperature changes. It reminded me of protein crystallization:

→ Right conditions
→ Patience
→ Creativity

It's all about balance, whether in a lab or nature.

#Crystallization

18.02.2025 02:12 — 👍 3    🔁 0    💬 0    📌 0
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The Evolution of Structural Biology

1958: Decades of grinding calculations & whale meat to map myoglobin.
2024: AI predicts & designs proteins in seconds.
Enzymes 60,000x faster?
Plastic-eating nanorings?

#AI #ProteinDesign #StructuralBiology

17.02.2025 06:21 — 👍 2    🔁 0    💬 0    📌 0
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Are X-ray crystallography, cryo-EM, and NMR competitive or complementary?

Each has strengths and limitations—high resolution, flexibility, or dynamic insights. The future of structural biology lies in integration!

What’s your take?
#StructuralBiology #CryoEM #NMR #XrayCrystallography

16.02.2025 19:25 — 👍 3    🔁 0    💬 0    📌 0
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X-ray Crystallography 🆚 Cryo-EM 🆚 NMR

Are X-ray crystallography, Cryo-EM, and NMR competitive or complementary? 🤔

Think solving a puzzle—do you want sharp atomic details, a near-native image, or a dynamic view?

#StructuralBiology #XrayCrystallography #CryoEM #NMR

16.02.2025 04:49 — 👍 9    🔁 1    💬 0    📌 0

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