Assistant Professor (Research %26 Education)
Click the link provided to see the complete job description.
๐จ New Assistant Professor Position ๐จ
Come join the CPBM at Durham University! If you are interested in running a lab in AI-based biomolecular design and bionanotechnology please get in touch and apply!
tinyurl.com/skwr65ua
@cpbm-heddlelab.bsky.social
@durham-university.bsky.social
03.09.2025 12:05 โ ๐ 3 ๐ 1 ๐ฌ 0 ๐ 0
Scaling down protein language modeling with MSA Pairformer
Recent efforts in protein language modeling have focused on scaling single-sequence models and their training data, requiring vast compute resources that limit accessibility. Although models that use ...
Excited to share work with
Zhidian Zhang, @milot.bsky.social, @martinsteinegger.bsky.social, and @sokrypton.org
biorxiv.org/content/10.1...
TLDR: We introduce MSA Pairformer, a 111M parameter protein language model that challenges the scaling paradigm in self-supervised protein language modeling๐งต
05.08.2025 06:29 โ ๐ 95 ๐ 43 ๐ฌ 1 ๐ 1
Stay tuned for details on the 6th edition of MLSB, officially happening this December in downtown San Diego, CA!
28.07.2025 15:41 โ ๐ 15 ๐ 7 ๐ฌ 0 ๐ 0
I am super excited to announce that I will be starting my lab at the Department of Pharmacology of the University of Zurich in Switzerland next year!
25.07.2025 07:48 โ ๐ 218 ๐ 39 ๐ฌ 23 ๐ 5
There's not enough zigging or zagging the prequels.
22.07.2025 09:05 โ ๐ 3 ๐ 0 ๐ฌ 0 ๐ 0
Our paper on:
A coarse-grained model for simulations of phosphorylated disordered proteins
(aka parameters for phospho-serine and -threonine for CALVADOS)
is now published in Biophysical Journal
authors.elsevier.com/a/1lTcE1SPTB...
@asrauh.bsky.social @giuliotesei.bsky.social & Gustav Hedemark
22.07.2025 05:58 โ ๐ 41 ๐ 13 ๐ฌ 1 ๐ 1
Protein structure alignment significance is often exaggerated https://www.biorxiv.org/content/10.1101/2025.07.17.665375v1
20.07.2025 04:46 โ ๐ 4 ๐ 1 ๐ฌ 0 ๐ 0
A few years ago, one could only dream of doing this. It so exciting seeing this work from the @adamrbentham.bsky.social lab. Of course, I am biased by the rice NLR pair and the Magnaporthe effector they chose ๐๐
#2025ISMPMI
17.07.2025 13:51 โ ๐ 19 ๐ 2 ๐ฌ 0 ๐ 0
Definitely keen!
15.07.2025 13:24 โ ๐ 3 ๐ 0 ๐ฌ 0 ๐ 0
AlphaFlex: Accuracy modeling of protein multiple conformations via predicted flexible residues https://www.biorxiv.org/content/10.1101/2025.07.11.664327v1
14.07.2025 16:47 โ ๐ 5 ๐ 2 ๐ฌ 0 ๐ 0
Travelling to Kรถln for Heath's first MPMI! #2025ISMPMI
11.07.2025 15:38 โ ๐ 35 ๐ 3 ๐ฌ 1 ๐ 0
Thrilled to share our latest preprint! This work started during my PhD and was finished together with @jmadhuprakash.bsky.social. We found a Phytophthora infestans L-shaped effector that bridges a host TOL protein to activated NLRs to suppress immunity!
www.biorxiv.org/content/10.1...
1/15
09.07.2025 13:03 โ ๐ 56 ๐ 17 ๐ฌ 2 ๐ 2
Ahn Lab is going to MPMI! #2025ISMPMI
Hayden Burdett and myself will be attending the MPMI conference in Cologne โช
Check out poster P-073 for paired NLR biology, and let's chat about paired NLRs and more!๐ฑ
See you in Cologne ๐
@instmolplantsci.bsky.social
11.07.2025 15:01 โ ๐ 33 ๐ 5 ๐ฌ 0 ๐ 0
Pls repost ๐จI'm looking for someone excited about #proteindesign and #synbio to join my lab @Durham_Uni
at the CPBM @cpbm-heddlelab.bsky.social
to undertake a PhD using #synthetic knottins as novel #bioinsecticides. If you're interested please get in touch and check out the advert below ๐
28.02.2025 10:23 โ ๐ 17 ๐ 24 ๐ฌ 1 ๐ 0
Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors
Inorganic phosphate (Pi) is essential for life, and plant cells monitor Pi availability by sensing inositol pyrophosphate (PP-InsP) levels. In this work, we describe the hijacking of plant phosphate s...
๐ Plant pathogenic fungi hijack phosphate signaling with conserved enzymatic effectors
๐งโ๐ฌ Carl L. McCombe, Alex Wegner, Ely Oliveira-Garcia, Simon J. Williams, Ulrich Schaffrath, et al.
๐ @science.org
๐ www.science.org/doi/10.1126/...
#๏ธโฃ #PlantScience #PlantImmunity #PlantNutrients
28.02.2025 06:03 โ ๐ 32 ๐ 18 ๐ฌ 0 ๐ 0
promotional figure
Out in @elife.bsky.social ! ๐
Thank you @sohambio.bsky.social for your persistence! Also to @asimjaved.bsky.social & @jiaxuwu.bsky.social for your contributions! So excited to keep understanding gall-forming pathogens using these results as a starting point!
elifesciences.org/reviewed-pre...
21.02.2025 16:34 โ ๐ 29 ๐ 7 ๐ฌ 1 ๐ 3
Plant Science Research Weekly: February 21, 2025 | Plantae
Perspective: How should the advancement of large language models affect the practice of science? In this thought-provoking Perspective, four sets of authors express their opinions about the use ofโฆ
Plant Science Research Weekly Feb 21 plantae.org/plant-scienc.... Roles of large language models in science? Apoplastic pH modulates H2O2 redox potential; Balancing signal specificity in stomatal development and defense; Hydropatterning in maize inbred lines; Bacterial cellulose boosts regeneration
21.02.2025 07:35 โ ๐ 13 ๐ 5 ๐ฌ 1 ๐ 0
Hi all!!! ๐
New to Bluesky, but...
I'm hiring a Postdoctoral Research Fellow at The Martin Luther University Halle-Wittenberg...
www.verwaltung.uni-halle.de/dezern3/Auss...
Please repost if you can!!
Thank you!!!
14.02.2025 22:35 โ ๐ 21 ๐ 31 ๐ฌ 0 ๐ 1
A meme with 4 panels showing a lichen with a cartoonish face drawn on it. The text says: โA lichen sits in a community. Is the community made of lichen? Or is the lichen made of community? It screams, for it does not knowโ.
Our study on #lichen #symbiosis is out in @currentbiology.bsky.social! How can multiple microbes create a large, 3D, and structurally complex organism? To answer this question, we used #metagenomics, #metatranscriptomics, and a bit of protein structure modeling ๐งต1/7
๐งฌ ๐ฅ๏ธ ๐งช ๐ฆ ๐งซ #SymbioSky
31.01.2025 16:34 โ ๐ 208 ๐ 61 ๐ฌ 7 ๐ 4
Protein language models excel at generating functional yet remarkably diverse artificial sequences.
They however fail to naturally sample rare datapoints, like very high activities.
In our new preprint, we show that RL can solve this without the need for additional data:
arxiv.org/abs/2412.12979
18.12.2024 21:06 โ ๐ 58 ๐ 15 ๐ฌ 1 ๐ 1
An immune signalling holiday tale: A Poales-specific EXO70 clade doesn't fit in with the extended family. #PlantScience
17.12.2024 23:12 โ ๐ 12 ๐ 11 ๐ฌ 1 ๐ 0
๐ฌ Postdoc at John Innes Centre, Norwich (Sablowski group) | ๐ฑ Cell size regulation
๐งฌ PhD in Lieve Gheysenโs lab, Ghent University | Nematode effectors & plant immunity
Editor in Chief of the #NonProfit, #OpenAccess journal @plosbiology.org Former Chief Editor of Nature Microbiology.
#Virologist. #Feminist. #Spaniard in the UK. #Galician. #European always.
Views my own.
https://orcid.org/0000-0002-3666-5683
Synthetic biologist, passionate about levelling the playing field in bioinnovation - open source biostack.
Open Science Network Society, Creator of the Open Yeast Collection and Yeast Protein Expression Toolkit, Reclone.org, iGEM Eng. Team, FreeGenes
Interested in fungi and plant-pathogen interactions๐ฑ currently working with @talbotlabtsl.bsky.social ๐ฎ๐จ๐ฆ๐ท๐ฌ๐ง
Interested in Plant Immunity, Researcher in Kemmerling Lab, ZMBP, Tรผbingen, DAAD Scholar at TU Mรผnich, MTech in IIT Kharagpur
BBSRC Discovery Fellow / Assistant Professor @warwicklifesci.bsky.socialโฌ
Mad about Plant Cell Biology / Cytoskeleton / Organelle Dynamics
Post doctoral research associate in the CoX lab at @Washington University at St. Louis!
Former PhD student @Indiana University Bloomington at Roger Innes's lab studying plant-fungal intercations!
Interested in plant pathogen and plant communication!
A Postdoc at The Sainsbury Laboratory, Norwich ๐ฌ๐ง working on vegetable NLR networks ๐ฅฌ & An instructor at Sciences Faculty (Biology), Kasetsart University, Thailand ๐น๐ญ
PhD student in plant pathology at Penn State | UW Madison alumna
๐ฟ Asst Prof. #NewPI. Molecular host-bacterial-fungal interactions. NCSSM/NCSU/Cornell alum. Y'all means all. Views are my own. she/her
HHMI Hanna Gray Fellow | Asst. Professor @ WashU & Asst. Member @ Danforth Center | Spatial Biology | Plant-microbe Interactions | Duckweed | YouTuber/Streamer | www.thecoxlab.org/
Royal Society University Research Fellow
at the Institute of Molecular Plant Sciences
Interested in plant immunity and protein complex assembly
Lecturer and Researcher @ Leiden University of Applied Science/Hogeschool Leiden | Plant biology | Metagenomics | Education |๐ฟ๐งฌ ๐ช๐บ
Dad of two, Professor, Lister Research Fellow and Wellcome Investigator at the John Innes Centre. Interested in bacterial chromosome organization & segregation, plasmids, and phages.
www.tunglelab.org
Postdoc in plant-pathogen interactions, currently researching the molecular interactions between Zymoseptoria tritici and the wheat immune system
Research by IMPS staff addresses the global challenges of food security, green technology and climate change. Account run by the IMPS Outreach committee
Science Events helps you organise a scientific conference or workshop. Use our platform to organise your next event! Visit our platform at https://www.sci.events
Accociate Professor at Durham University