Meghan Riddell

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Congrats and welcome home Felix!!

WCHRI members are doing amazing things and I can honestly say WCHRI fosters one of the best environments to do perinatal research in the world. Check out what they did this year!

Want an exciting opportunity that merges academia and industry? Interested in fertility, method development or embryogenesis? Then come join our teams for a fully funded postdoctoral fellow position!🧬🧫

Microvilli are required for placental cell fusion

Read this Research Highlight showcasing work from @wendykduan.bsky.social,
@meghanriddell.bsky.social & collegaues:
journals.biologists.com/dev/article/...
🎥12wk gestational age placental tissue 24hrs posttrypsinization

Meghan Riddell (left) and Wendy Duan (right)

To learn more about the story behind the paper, we caught up with first author Wendy Duan @wendykduan.bsky.social and corresponding author Meghan Riddell @meghanriddell.bsky.social, Associate Professor at the University of Alberta, Canada:
journals.biologists.com/dev/article/...

two men in suits and ties are sitting next to each other in front of a window with blinds . ALT: two men in suits and ties are sitting next to each other in front of a window with blinds .

And now that she has joined I can tag @wendykduan.bsky.social
And @sumaiyahshaha.bsky.social
and the rest of the lab for their incredible teamwork on this project.

Thanks to NSERC, @wchriuofa.bsky.social , @ualberta.bsky.social for their support

We also developed two different trophoblast villous lineage models for this work: a bioreactor trophoblast stem cell organoid model and a placental explant regeneration model

So check them out!

bart simpson is sitting at a table with a glass of water and a plate of food ALT: bart simpson is sitting at a table with a glass of water and a plate of food

We asked whether we could quantify shape changes in placental cytotrophoblasts that are preparing to fuse and discovered they require microvilli to fuse.

Cytotrophoblasts develop cute little Bart Simpson heads along the way to fusion

Placental cytotrophoblast microvillar stabilization is required for cell-cell fusion Summary: Fusion-competent cytotrophoblasts undergo dynamic changes in cell morphology, including the acquisition of apically localized microvilli, the stabilization of which facilitates effective fusi...

Thrilled to see this work published! track.smtpsendmail.com/9032119/c?p=...

Congratulations! Sorry to lose you but excited to see what your next chapter looks like.

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Were looking for a Tier 2 CRC in Human Metabolic Disease!

Just posted but hurry as app deadline is May 15!

Got expertise in #obesity or #diabetes and are an emerging expert in your field?

Apply now!!!!

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Always so fun to get together! See you all soon

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Congratulations Serge and team 🥳

Don’t miss out on this opportunity to grow your mentor network at #SRI2025

Thank you!! Hope things are great with you!

Thanks Ruben!! Hopefully see you soon

Honoured to be named a Canada Research Chair in Maternal-Fetal Interface biology in health and disease 🥳 thank you for the support @ualberta.bsky.social and to this amazing team who make it so much fun!

Upcoming Development Special Issue 'Lifelong Development'

Beyond the embryo: tissue maintenance, regeneration & plasticity

Guest eds: Meri Huch & Mansi Srivastava

Deadline: 15 May 2025 All article types welcome #DevBio #Regeneration #StemCells

journals.biologists.com/dev/pages/li...