Erin E. Cutts

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It's more important than ever for students and educators to stay informed and proactive. That's why you're invited to our upcoming webinar “The Future of Graduate Education in Biophysics"

September 4, 3:30-5:00PM USA Eastern
my.biophysics.org/events/calen...

Starting off our NAF 2025 meeting with an introduction of the RSC Nucleic Acids Group's new chair, Marco Di Antonio! An exciting new era for our group begins! 🧬
@diantoniogroup.bsky.social

This is a proper tour de force of integrative structural biology and biochem! (Including from our own @eecutts.bsky.social @mcb-sheffield.bsky.social) so many crucial roles for SLiMs in fundamental cellular processes.

Condensin II activation by M18BP1 Borsellini, Conti, Cutts, Harris, et al. identify an interaction between M18BP1 and condensin II that is essential for condensin II activity and chromatin localization. MCPH1 keeps the interphase geno...

Condensin II activation by M18BP1: Molecular Cell www.cell.com/molecular-ce...

JOB OPENING for biochemist/-physicst 🧑‍🔬: This isn't an official job ad yet. We are looking for a postdoc working on large to high throughout single-molecule FRET on protein structures and dynamics. The project will be run in our lab and co-directed jointly with a team from big pharma/biotech. 1/2

Job Alert 🔊🔊
Looking for your first or next Postdoc position? Then don't look further, apply to this opportunity to join our lab to tackle the next big challenges in the Wnt signalling field. Experience in protein biochemistry and in vitro cell biology is essential for this post tinyurl.com/2p9rndfy

I was really hoping you were going to post some puppy party photos. There can never be too many puppy pictures in the world.

Different author, but this was one of the worst ones I found, deposited as 3.2A, published in NSMB. I emailed the authors and they saw no issue depositing the structure where only half the density was there...

Senior lecturer in medical biochemistry - Uppsala University Senior lecturer in medical biochemistry , Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology, Uppsala University

Looking for a senior lecturer (associate #professor) position in #biochemistry? Come and join our neighbouring department at Uppsala University: www.uu.se/en/about-uu/...

Less than two weeks to go! Thanks for all the donations!

www.justgiving.com/team/thalia

YouTube video by Johan Gibcus Rules of Engagement

Earnshaw, Goloborodko, Dekker & Mirny labs are excited to present our latest work, "Rules of engagement for condensins and cohesins guide mitotic chromosome formation" - now accepted!!
www.science.org/doi/10.1126/...
A short clip describing the key results:
www.youtube.com/watch?v=pmvO...

Substrate recognition by human separase The protein complex cohesin encircles the sister chromatids in early mitosis. At anaphase onset, sister separation is triggered by cleavage of the cohesin subunit SCC1/RAD21 by the cysteine protease s...

Fantastic new work on substrate recognition by separase!

www.biorxiv.org/content/10.1...

Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield on FindAPhD.com PhD Project - Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield, listed on FindAPhD.com

Anyone looking for a PhD: the second deadline of the Yorkshire DTP closes this Friday, the 14th. Get in touch asap if you are interested in working with me on condensin complexes!
www.findaphd.com/phds/project...

Deadline for abstract submission (for poster/short talk presentation) extended until March 14 - after that we will open registration for scientific participants without abstracts.

Another fave

Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles - Nature Communications Constructing synthetic prototissues is a challenge in bottom-up synthetic biology. Here, the authors introduce a “lipid foam” tissue mimetic and demonstrate network-wide tension fluctuations upon comp...

Very happy to see this out! 😍

Tissue-like lipid networks with motile bacteria undergo large remodeling events, leading to active “hubs” & tissue fluidization!

This was a super fun collab w Jan Steinkuhler lab!

www.nature.com/articles/s41...

Don’t miss the early bird registration for this exciting meeting focused on neglected areas of genetics, cellular and structural biology. Lots of slots for speakers selected from abstracts. 2-4 April 2025 in Edinburgh.

Development folks: the next Northern England Developmental Biology @bsdb.bsky.social @biologists.bsky.social meeting will take place on the 10th of July in Sheffield. Great speaker line-up, cheap registration fee and plenty of slots for ECR talks. Registration deadline=31/5, see poster for details

Oh that’s so sad!

Science Of The Times Do you want to learn a little more about topical science findings? Do many of the science stories you hear leave you with unanswered questions? Syma and Tim will discuss in non-technical language and ...

Our first introductory episode will go live tomorrow!

@timcoulson.bsky.social @sykhalid.bsky.social @streamingspires.bsky.social

scienceofthetimes.transistor.fm

Happy to report our enzyme found a home! rdcu.be/eaGXG New kid on the block P450 O-demethylase SyoA-the specificity of a monooxygenase with the simplicity of catalysis driven by peroxide. Retrofit your P450 with this active site chemistry today! #lignin #syringol Out today in Nature Communications.

A view a across a park in the sun after rain

There are certainly worse office views

The UK&Ireland single-molecule meeting 2025 will be held in Oxford on May 14 and 15 - deadline for abstract submission March 7 - submit one and join us! Here is the link:
lumicks.com/uk-single-mo...

Cohesin drives chromatin scanning during the RAD51-mediated homology search Cohesin folds genomes into chromatin loops, whose roles are under debate. We report that double strand breaks (DSB) induce de novo formation of chromatin loops, with the break positioned at the loop b...

Beautiful work showing how DSBs trigger de novo cohesin loops, positioned perfectly at break sites. RAD51 spreads ~Mb within TAD limits & loop extrusion actively drives homology search - distant HR repair drops when you kill cohesin loading by NIPBL! #DNArepair
www.biorxiv.org/content/10.1...

Check out our journey to #BPS2025

See you there at Booth 410!

Still a limited number of tickets for our happy hour available so come by the booth!

I play this fun game with my husband in the lead up to valentines where we joke about getting each other gifts/cards with the understanding that we do not do anything for Valentine’s Day. One day one of us might ruin it and buy something romantic, but for now it’s a fun game.

Postdoctoral Training Fellow in Chelsea | The Institute of Cancer Research View details and apply for this Postdoctoral Training Fellow vacancy in Chelsea . Salary: Dependent on relevant Postdoctoral experience. Future progression is based on annual performan...

At #EMBOinsitu and looking for a motivated postdoc joining an interdisciplinary project in my lab:
jobs.icr.ac.uk/vacancies/11...
the-alfieri-lab.co.uk
#cryoem #cryotem

I had a wonderful time presenting and talking to everyone at the University of Leeds! Thanks so much for hosting @qianwu5000.bsky.social

Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield on FindAPhD.com PhD Project - Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield, listed on FindAPhD.com

For anyone that was too busy at the end of last year to think about PhDs or are still looking for the right project/place, I have a project available in the second round of the Yorkshire Biosciences DTP scheme looking at the dynamics of human condensin:
www.findaphd.com/phds/project...

Research Fellow at University of Birmingham Discover an exciting academic career path as a Research Fellow at jobs.ac.uk. Don't miss out on this job opportunity - apply today!

My lab is #hiring!

I am recruiting for two #Postdoc positions investigating the Alternative Lengthening of Telomeres mechanism.

www.jobs.ac.uk/job/DLO693/r...

www.jobs.ac.uk/job/DLP016/r...

#Telomere #DNAreplication #DNArepair #cancer #glioma #UKRI #MRC #universityofbirmingham #NGS