Martin Lauritzen

Showing how a precapillary sphincter dilates during high blood pressure

🐭🧠 #PrecapillarySphincters (PS) at the #arteriole–#capillary junction rapidly dilate ~30% in seconds during #SensoryStimulation—regulating #capillary #BloodFlow dynamically. Here we investigated whether they protect downstream microvessels during abrupt #BloodPressure surges 🧪🧵

10.06.2025 19:38 — 👍 19    🔁 8    💬 2    📌 2

A budget for brain metabolic water production by glucose catabolism during rest, rises in activity and sleep - Fluids and Barriers of the CNS Maintaining brain fluid homeostasis is of critical importance for creating a stable environment conducive to optimal neuronal functioning, nutrient distribution, and waste product removal. In this stu...

Your brain functions not only as a thinking organ but also as a miniature water factory. We here calculate how much water neuronal mitochondria produce by glucose oxidation: 300-400 ml. Of that amount, 100 ml go into brain's interstitial fluid. fluidsbarrierscns.biomedcentral.com/articles/10....

06.05.2025 18:21 — 👍 12    🔁 6    💬 0    📌 0

The cerebral blood flow response to neuroactivation is reduced in cognitively normal men with β-amyloid accumulation - Alzheimer's Research & Therapy Background Accumulation of β-amyloid (Aβ) in the brain is a hallmark of Alzheimer’s Disease (AD). Cerebral deposition of Aβ initiates deteriorating pathways which eventually can lead to AD. However, t...

Once again, someone else says it: "Aβ accumulation affecting brain vessel function could be a very early pathology leading to neurodegenerative disease." doi.org/10.1186/s131... #cerebrovascular

06.01.2025 15:35 — 👍 24    🔁 8    💬 0    📌 0

The cerebral blood flow response to neuroactivation is reduced in cognitively normal men with β-amyloid accumulation - Alzheimer's Research & Therapy Background Accumulation of β-amyloid (Aβ) in the brain is a hallmark of Alzheimer’s Disease (AD). Cerebral deposition of Aβ initiates deteriorating pathways which eventually can lead to AD. However, t...

The cerebral blood flow response to neuroactivation is reduced in cognitively normal men with β-amyloid accumulation

alzres.biomedcentral.com/articles/10....

06.01.2025 16:19 — 👍 9    🔁 4    💬 0    📌 0

This is not what the paper describes nor what was written in the perspective. The paper show antero- and retrograde flow of CSF in foramina Luschka and Magendie during deep sleep.

01.12.2024 08:34 — 👍 2    🔁 0    💬 0    📌 0