PJP

PJP

@pjp04.bsky.social

ID physician and TB enthusiast. Views my own.

802 Followers 1,065 Following 1 Posts Joined Nov 2024
11 months ago
Preview
A natural experiment on the effect of herpes zoster vaccination on dementia - Nature Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...

Very compelling study showing the association between herpes zoster vaccination and dementia prevention. The authors leveraged a unique cohort for this natural experiment which shows a reduction in dementia risk of 20% in vaccinated individuals. #MedSky #IDSky 🧪
www.nature.com/articles/s41...

459 135 10 8
11 months ago
Post image Post image

(🧵) Hear from our patients and specialists as they share their experiences with tuberculosis (TB).

Follow the thread 👇

9 6 1 0
1 year ago
Preview
Finland ends homelessness and provides shelter for all in need - scoop.me In Finland, the number of homeless people has fallen sharply. Why? The country applies the "Housing First" concept agains homelessness.

“In Finland, the number of homeless people has fallen sharply. Those affected receive a small apartment & counselling with no preconditions. 4 out of 5 people affected make their way back into a stable life. And all this is CHEAPER than accepting homelessness.”

43,051 14,139 861 1,390
1 year ago
Preview
Local Solutions for Global Impact: New Microbiology Lab Opens in Sierra Leone The cutting-edge lab is a central hub for PIH-supported Koidu Government Hospital, providing test results for patients and clinicians across all departments.

PIH Sierra Leone & the Ministry of Health just opened a cutting-edge microbiology lab at Koidu Gov. Hospital!

With advanced technology and expert-led training, clinicians can now make informed decisions, reducing the misuse of antibiotics and improving patient outcomes: www.pih.org/article/loca...

29 3 0 0
1 year ago
Post image Post image Post image Post image

It is also one of the most beautiful countries in the world with the most amazing, resilient and warm people. I know so many people doing meaningful and lifesaving work against the odds.

4 0 1 0
1 year ago
Preview
endTB Trial Paves Way for Shorter, Cheaper, and Safer Rifampin-Resistant TB Treatments Carole Mitnick, ScD discusses the impact of the endTB trial's findings on future TB treatment options, including shorter treatment durations, lower costs, and expanded accessibility.

Part 2 w/ Dr. @cdmitpih.bsky.social from @harvardmed.bsky.social discusses the #endTB trial & how it’s changing RR-TB treatment with 9-month, all-oral regimens that are more affordable and accessible, along with future directions for the field. #IDsky #MEDsky

www.contagionlive.com/view/endtb-t...

5 3 0 2
1 year ago

Thx for sharing our endTB results. Too bad u weren’t able to include my comment on the chilling effect on medical advances in TB, HIV, cancer, heart disease, etc. wrought by current US leadership. endTB was possible only bcuz of trust cultivated over decades.½

6 2 1 0
1 year ago

For those who thought TB was a disease of the past, it’s not. For those who thought TB was fully preventable & curable, it is. For those who can’t reconcile these facts & that 1.5 million people die of TB, each year…½🧵

8 3 1 0
1 year ago
Post image

“We know how to live in a world without tuberculosis. But we choose to not live in that world”

I’m so excited to read @johngreensbluesky.bsky.social new book!!

Please stay tuned for my interview with John in March!

everythingistb.com

105 22 3 1
1 year ago
Preview
Clinician Call: Update on Avian Flu

You can watch the Jan 23 IDSA Clinician Call on H5N1 avian influenza here: www.idsociety.org/multimedia/c...
#IDSky #MedSky #EpiSky

12 2 1 0
1 year ago
Preview
Need to Know: Treatment Supporters Learn why they are essential to tuberculosis care.

Fighting TB takes a team💪

In Lesotho, we rely on dedicated individuals known as treatment supporters to ensure TB patients stay on track with their treatment through daily home visits & connecting patients with essential resources.

Learn more about treatment supporters: www.pih.org/article/need...

11 4 0 0
1 year ago
Preview
Virologic failure and emergent integrase strand transfer inhibitor drug resistance with long acting cabotegravir for HIV treatment: A meta-analysis Although 48-week virological failure rates were low, emergent integrase resistance among those failing injectable cabotegravir was common (41-71%), and cro

Potential impact of increasing CAB/RPV use on the future efficacy of INSTIs as first-line therapy for HIV.

#IDsky #HIVsky

@cidjournal.bsky.social

academic.oup.com/cid/advance-...

27 10 2 1
1 year ago
Preview
Tuberculosis rates plunge when families living in poverty get a monthly cash payout A program in Brazil that gives a monthly cash sum to families living in poverty has an unexpected — and welcome result. A new study shows that it is dramatically reducing tuberculosis rates.

"The study is impressive in its scale...cases and deaths dropped by more than 50% and in the Indigenous population the drop was even more dramatic: more than 60%."

Nature Medicine study shows the effects of Bolsa Familia strongest in Black and Indigenous populations

www.npr.org/sections/goa...

680 248 12 27
1 year ago
On the Inpatient ID Consult Service, Oral Antibiotics Have a Rocky Road to Acceptance Having just completed a stint doing inpatient ID consults, I came away impressed with three things: Staph aureus remains the Ruler of Evil Invasive Pathogens in the hospital setting. You can “jinx” a ...

Though "Oral is the New IV" with antibiotics (h/t @bradspellberg.bsky.social), it's not always easy to convince reluctant inpatient clinicians -- especially (in my experience) surgeons, who want to treat "aggressively".

Interesting dynamic ...
blogs.jwatch.org/hiv-id-obser...

89 24 11 7
1 year ago
Preview
Tuberculosis rates plunge when families living in poverty get a monthly cash payout A program in Brazil that gives a monthly cash sum to families living in poverty has an unexpected — and welcome result. A new study shows that it is dramatically reducing tuberculosis rates.

There’s a good reason why we call tuberculosis a social disease

TB rates plunge when families living in poverty get a monthly cash payout

www.npr.org/sections/goa...

227 79 0 4
1 year ago
An illustration of Capitol Hill with the TBFighters hourglass and the sun behind it. Above it is the text "Sign up for the Hill Day! April 8th-9th. Washington DC. Online or in-person. Sign up and learn more: tbfighters.com/hill-day. Deadline: Dec. 31st"

Is making a difference in your community (& around the world) one of your New Year's resolutions? Join us virtually or in person for a #Tuberculosis Hill Day in April 2025! The deadline to commit is December 31: tbfighters.org/hill-day

133 32 0 2
1 year ago
Post image

🏥 On the fourth day of PIH, we’re celebrating a breakthrough in the fight against TB! Four new, short, and highly effective treatments from the EndTB trials have been approved by the WHO.

This marks a significant step forward in combating TB

Learn more: www.pih.org/press/major-...

11 5 1 0
1 year ago
Post image

Meet Lecsame Joseph, a dedicated farmer from Pignon, Haiti 🇭🇹

After years of working as a mechanic and taxi driver in Port-au-Prince, Joseph was diagnosed with diabetes. 🧵

0 1 1 0
1 year ago
Post image

On the third day of PIH: Discover how 3 health programs reflect Diné culture on Navajo Nation 🧡

From culturally aligned care to honoring traditions, see how health care + heritage come together for Navajo communities.

Read more: www.pih.org/article/thre...

3 1 1 0
1 year ago
Post image


Let’s kick off with Day 1: PIH Sierra Leone launched the country’s first-ever mental health hotline!

This groundbreaking initiative delivers vital mental health support to those who need it most.

Learn how this project is transforming lives: www.pih.org/article/pih-...

10 2 1 0
1 year ago
Post image

Welcome to the 11 Days of PIH ❄️🎉

As the year wraps up, we celebrate the incredible impact we've achieved together. Over the next 11 days, we’ll highlight stories showcasing the work we’ve accomplished, the lives we’ve changed, and the progress we’ve driven in global health. 🧵

15 7 1 0
1 year ago
Post image

📣 On the second day of PIH, we’re inviting YOU to take action! In less than two minutes, you can contact your rep and urge them to support the End TB Act.

Together, we can make strides in ending one of the world’s deadliest diseases.

Take action today: act.pih.org/end-tb-now-a...

9 9 1 1
1 year ago
Post image

I ❤️ science!

Bedaquiline is an amazing drug for tuberculosis, greatly shortening DR-TB treatment

But it also works for leprosy (another ancient mycobacterial infection)!

In patients with multibacillary leprosy, bedaquiline cleared M. leprae in 4 weeks

www.nejm.org/doi/full/10....

183 41 3 2
1 year ago
Post image

This year, our photographers captured the heart of our work: from a canoe helping families reach hospitals in Liberia, to community health workers delivering care 📸

These are a few of the stories that made 2024 unforgettable!

Explore our favorite photos: www.pih.org/article/our-...

6 5 0 0
1 year ago

While attention is trained on the potential infectious cause which could spread internationally, we should not ignore that food insecurity, malnutrition and lack of access to basic health needs seems to be the major driver of bad outcomes here. All social determinants of health enhanced by inequity.

109 33 4 2
1 year ago
Post image

Don't you just love a good disease primer. Especially for neglected rare diseases we don't see in clinical practice on the daily. This #leprosy primer in nature reviews is great and comes with a snapshot summary that's very digestible.
#IDSky #MedSky
www.nature.com/articles/s41....

98 24 7 1
1 year ago
Preview
Ten years ago Ebola tore through Sierra Leone. Can a vaccine drive stop history repeating itself? Memories of 2014, when the disease ravaged west Africa, are raw, while risk remains high. This week the first ever nationwide prevention programme begins – and doctors hope it will be enough to fend o...

Sierra Leone will this week become the 1st country to launch a nationwide preventive #Ebola vaccination campaign for people at the highest risk. Over 3 weeks, will deliver 20k doses of Merck’s Ervebo vaccine in a drive that will be repeated every 2-3 years. #IDSKY
www.theguardian.com/global-devel...

294 77 7 3
1 year ago
Preview
Implementation of Injectable Cabotegravir/Rilpivirine for Treatment of Human Immunodeficiency Virus in Patients With Substance Use Disorders at a Syringe Exchange Clinic This case series looks at the two-year implementation of Injectable Cabotegravir+ Rilpivirine (CAB+RPV-LA) in a syringe exchange clinic with patients who h

Injectable HIV treatment is feasible via syringe services programs
academic.oup.com/ofid/article...
#IDsky @jessmeisner.bsky.social

15 5 0 1
1 year ago
Preview
Fight or Flight — Facing the Marburg Outbreak in Rwanda | NEJM Having diagnosed two ICU patients with the first known cases of Marburg virus disease in Rwanda, a physician must prioritize limiting spread, despite pleas for transfer from the patients’ families.

Poignant frontline perspective of a #Rwandan physician responding to the recent #marburg outbreak. It is well worth a read. We are are two weeks into the 42 day countdown to declaring the outbreak over🤞🏾. These brave HCPs kept us safe. #medsky #idsky 🧪
www.nejm.org/doi/full/10....

334 89 9 4