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ATS PITB Assembly

@ats-pitb.bsky.social

89 Followers  |  64 Following  |  107 Posts  |  Joined: 27.11.2024  |  1.9145

Latest posts by ats-pitb.bsky.social on Bluesky

Upper-Airway Microbiome, Mucociliary Function, and Clinical Outcomes in Bronchiectasis: Data from the EMBARC-BRIDGE Study | American Journal of Respiratory and Critical Care Medicine Rationale: Infection is a key disease driver in bronchiectasis, and the upper-airway microbiome has been known to shape the lower-airway microbiome.

โœจ Recently published in AJRCCM: Data from the EMBARC-BRIDGE study show a key link between the upper-airway microbiome and clinical outcomes in patients with bronchiectasis.

www.atsjournals.org/doi/epdf/10....

10.12.2025 20:46 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐ŸงชMeet our @ATS_PITB Assembly Early Career Highlight, Dr. Pramod Bhattarai!๐Ÿ”ฌ Dr. Bhattarai serves rural and underserved communities and his research focuses on health disparities, particularly in people living with HIV. ๐Ÿงซ When out of the clinic, he enjoys coin collecting ๐Ÿช™ and hiking ๐Ÿฅพ!

09.12.2025 16:12 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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A Pragmatic Trial of Glucocorticoids for Community-Acquired Pneumonia | NEJM Adjunctive glucocorticoids may reduce mortality among patients with severe community-acquired pneumonia (CAP) in well-resourced settings. Whether these drugs are beneficial in low-resource settings...

In the SONIA trial, adjunct low-dose glucocorticoid use in patients hospitalized with CAP in a low-resource setting was associated with lower 30-day all-cause mortality compared with standard care. #NEJM

www.nejm.org/doi/full/10....

08.12.2025 16:36 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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COVID-19 mRNA Vaccination and 4-Year All-Cause Mortality Among Adults in France This cohort study uses the data from all adults aged 18 to 59 years living in France on November 1, 2021, to evaluate whether there is an association of receipt of an mRNA COVID-19 vaccine with long-t...

A cohort study of 28 million individuals aged 18โ€“59 found no increased risk of 4-year all-cause mortality among those vaccinated against COVID-19. #JAMA

jamanetwork.com/journals/jam...

05.12.2025 19:13 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Systemic Corticosteroids, Mortality, and Infections in Pneumonia and Acute Respiratory Distress Syndrome : A Systematic Review and Meta-analysis - PubMed None. (PROSPERO: CRD42024536301).

Soulmate et al.โ€™s meta-analysis showed, with moderate certainty of evidence, that adjunctive low-dose, short-course corticosteroids probably reduce short-term mortality in both severe PNA and ARDS.

pubmed.ncbi.nlm.nih.gov/41325621/

03.12.2025 16:53 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ“ข๐Ÿ“ข๐Ÿ“ขLess than a week left! Learn the latest on HIV-associated lung disease in the upcoming ๐ŸŒฒPINE Webinar on #worldaidsday December 1st! @idsainfo.bsky.social @atscommunity.bsky.social @btsrespiratory.bsky.social @theunion.org

Sign up here: thoracic.zoom.us/webinar/regi...

27.11.2025 02:37 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Selective Decontamination of the Digestive Tract during Ventilation in the ICU | NEJM Whether selective decontamination of the digestive tract (SDD) reduces mortality among patients undergoing mechanical ventilation and whether it adversely affects microbial ecology in the intensive...

Among mechanically ventilated patients, selective digestive decontamination did not reduce in-hospital mortality compared with standard care. #NEJM #PITB #SuDDICU

www.nejm.org/doi/full/10....

19.11.2025 20:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Leukocytic ADAM10 and ADAM17 modulate disease severity and systemic outcome in bacterial and viral pneumonia publications.ersnet.org/content/erj/...

18.11.2025 15:12 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
European Respiratory Society Clinical Practice Guideline for the Management of Adult Bronchiectasis BackgroundBronchiectasis is a common lung condition associated with wide range of infectious, immunological, autoimmune, allergic and genetic conditions. Exacerbations and daily symptoms have the largest impact on patients and healthcare systems, and they are the key focus of treatments. Current practice is heterogeneous globally, and bronchiectasis has historically been a neglected disease. Here, we present evidence-based international guidelines for the management of adults with bronchiectasis.MethodsA European Respiratory Society (ERS) Task Force, comprising global experts, a methodologist, and patient representatives, developed clinical practice guidelines in accordance with ERS methodology and the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) approach. Systematic literature searches, data extraction, and meta-analysis were performed to generate evidence tables, and recommendations were formulated using the evidence-to-decision framework. A total of 8 PICO (Patient, Intervention, Comparator, Outcomes) questions and 3 narrative questions were developed.RecommendationsThe Task Force recommendations include strong recommendations in favour of airway clearance techniques for most patients with bronchiectasis and pulmonary rehabilitation for those with impaired exercise capacity. We issue a strong recommendation for the use of long-term macrolide treatment for patients at high risk of exacerbations and a strong recommendation in favour of long-term inhaled antibiotics in patients with chronic Pseudomonas aeruginosa infection at high risk of exacerbation. Conditional recommendations support the use of eradication treatment or mucoactive drugs in specific circumstances. We suggest not to routinely use long term oral, non-macrolide antibiotic treatment or inhaled corticosteroids. Additional guidance is also provided on testing for underlying causes, managing exacerbations, and managing the deteriorating patient.ConclusionThe ERS bronchiectasis guidelines provide an evidence-based framework for optimal management of adults with bronchiectasis and serve as a benchmark for evaluating the quality of care.Scope and objectivesThe European Respiratory Society (ERS) guidelines for the management of bronchiectasis in adults provide evidence-based recommendations for the care of people with clinically significant bronchiectasis, defined by the presence of permanent dilatation of the bronchi evident on chest CT scan, along with characteristic clinical symptoms. [1] These guidelines are intended for all healthcare professionals involved in the care of adults with bronchiectasis, as well as for policymakers, regulatory authorities, and pharmaceutical companies. Bronchiectasis is a complex and heterogeneous disease; therefore, no guideline can be entirely comprehensive or replace clinical judgement. All guideline recommendations must be interpreted within the specific clinical context in which they are applied. Separate ERS guidelines for the management of bronchiectasis in children exist [2]. Bronchiectasis due to cystic fibrosis (CF) has a distinct evidence base; therefore, guidance for the management of CF is provided elsewhere. [3] Some bronchiectasis-associated conditions also have distinct guidelines for investigation and management, such as primary ciliary dyskinesia (PCD) [4], allergic bronchopulmonary aspergillosis (ABPA) [5] and non-tuberculous mycobacterial (NTM) pulmonary disease [6]. While the present guidelines apply for these conditions, they should be interpreted in conjunction with the relevant syndrome-specific recommendations.

๐Ÿšจ New 2025 ERS guidelines for the management of adult bronchiectasis! Takeaway:

Recommend to offer long-term macrolides to patients at high risk of exacerbations. High-risk features include P. aeruginosa infection, COPD, PCD, RA, and sputum purulence.

doi.org/10.1183/1399...

18.11.2025 02:09 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
European Respiratory Society Clinical Practice Guideline for the Management of Adult Bronchiectasis BackgroundBronchiectasis is a common lung condition associated with wide range of infectious, immunological, autoimmune, allergic and genetic conditions. Exacerbations and daily symptoms have the largest impact on patients and healthcare systems, and they are the key focus of treatments. Current practice is heterogeneous globally, and bronchiectasis has historically been a neglected disease. Here, we present evidence-based international guidelines for the management of adults with bronchiectasis.MethodsA European Respiratory Society (ERS) Task Force, comprising global experts, a methodologist, and patient representatives, developed clinical practice guidelines in accordance with ERS methodology and the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) approach. Systematic literature searches, data extraction, and meta-analysis were performed to generate evidence tables, and recommendations were formulated using the evidence-to-decision framework. A total of 8 PICO (Patient, Intervention, Comparator, Outcomes) questions and 3 narrative questions were developed.RecommendationsThe Task Force recommendations include strong recommendations in favour of airway clearance techniques for most patients with bronchiectasis and pulmonary rehabilitation for those with impaired exercise capacity. We issue a strong recommendation for the use of long-term macrolide treatment for patients at high risk of exacerbations and a strong recommendation in favour of long-term inhaled antibiotics in patients with chronic Pseudomonas aeruginosa infection at high risk of exacerbation. Conditional recommendations support the use of eradication treatment or mucoactive drugs in specific circumstances. We suggest not to routinely use long term oral, non-macrolide antibiotic treatment or inhaled corticosteroids. Additional guidance is also provided on testing for underlying causes, managing exacerbations, and managing the deteriorating patient.ConclusionThe ERS bronchiectasis guidelines provide an evidence-based framework for optimal management of adults with bronchiectasis and serve as a benchmark for evaluating the quality of care.Scope and objectivesThe European Respiratory Society (ERS) guidelines for the management of bronchiectasis in adults provide evidence-based recommendations for the care of people with clinically significant bronchiectasis, defined by the presence of permanent dilatation of the bronchi evident on chest CT scan, along with characteristic clinical symptoms. [1] These guidelines are intended for all healthcare professionals involved in the care of adults with bronchiectasis, as well as for policymakers, regulatory authorities, and pharmaceutical companies. Bronchiectasis is a complex and heterogeneous disease; therefore, no guideline can be entirely comprehensive or replace clinical judgement. All guideline recommendations must be interpreted within the specific clinical context in which they are applied. Separate ERS guidelines for the management of bronchiectasis in children exist [2]. Bronchiectasis due to cystic fibrosis (CF) has a distinct evidence base; therefore, guidance for the management of CF is provided elsewhere. [3] Some bronchiectasis-associated conditions also have distinct guidelines for investigation and management, such as primary ciliary dyskinesia (PCD) [4], allergic bronchopulmonary aspergillosis (ABPA) [5] and non-tuberculous mycobacterial (NTM) pulmonary disease [6]. While the present guidelines apply for these conditions, they should be interpreted in conjunction with the relevant syndrome-specific recommendations.

๐ŸšจNew 2025 ERS guidelines for the management of adult bronchiectasis! Key takeaway:

Recommend not offering long-term ICS to patients with bronchiectasis who do not have coexisting asthma or COPD.

doi.org/10.1183/1399...

14.11.2025 21:46 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Welcome! You are invited to join a webinar: Pulmonary Infections Network of Experts: A Case of HIV-Associated Lung Disease. After registering, you will receive a confirmation email about joining the w... Josalyn Cho, MD, University of Iowa, and Neelima Navuluri, MD, MPH, Duke University, will be discussing a case of HIV-associated lung disease to mark World AIDS Day, presented by Jonah Kreniske, MD, o...

๐Ÿ”ฅMark your calendars!๐Ÿ”ฅ
@ATS_PITB
is hosting a๐ŸŒฒPINE๐ŸŒฒWebinar on HIV-associated lung disease ๐Ÿซ Case-based discussion, with๐ŸŒglobal experts!
๐Ÿ“… Monday, December 1st 3PM ET
๐Ÿ—’๏ธRegister Here: thoracic.zoom.us/webinar/regi...
#TB @ATS_Assemblies
@IDSAInfo
@TheUnion_TBLH
@BTSrespiratory

13.11.2025 01:41 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
European Respiratory Society Clinical Practice Guideline for the Management of Adult Bronchiectasis BackgroundBronchiectasis is a common lung condition associated with wide range of infectious, immunological, autoimmune, allergic and genetic conditions. Exacerbations and daily symptoms have the largest impact on patients and healthcare systems, and they are the key focus of treatments. Current practice is heterogeneous globally, and bronchiectasis has historically been a neglected disease. Here, we present evidence-based international guidelines for the management of adults with bronchiectasis.MethodsA European Respiratory Society (ERS) Task Force, comprising global experts, a methodologist, and patient representatives, developed clinical practice guidelines in accordance with ERS methodology and the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) approach. Systematic literature searches, data extraction, and meta-analysis were performed to generate evidence tables, and recommendations were formulated using the evidence-to-decision framework. A total of 8 PICO (Patient, Intervention, Comparator, Outcomes) questions and 3 narrative questions were developed.RecommendationsThe Task Force recommendations include strong recommendations in favour of airway clearance techniques for most patients with bronchiectasis and pulmonary rehabilitation for those with impaired exercise capacity. We issue a strong recommendation for the use of long-term macrolide treatment for patients at high risk of exacerbations and a strong recommendation in favour of long-term inhaled antibiotics in patients with chronic Pseudomonas aeruginosa infection at high risk of exacerbation. Conditional recommendations support the use of eradication treatment or mucoactive drugs in specific circumstances. We suggest not to routinely use long term oral, non-macrolide antibiotic treatment or inhaled corticosteroids. Additional guidance is also provided on testing for underlying causes, managing exacerbations, and managing the deteriorating patient.ConclusionThe ERS bronchiectasis guidelines provide an evidence-based framework for optimal management of adults with bronchiectasis and serve as a benchmark for evaluating the quality of care.Scope and objectivesThe European Respiratory Society (ERS) guidelines for the management of bronchiectasis in adults provide evidence-based recommendations for the care of people with clinically significant bronchiectasis, defined by the presence of permanent dilatation of the bronchi evident on chest CT scan, along with characteristic clinical symptoms. [1] These guidelines are intended for all healthcare professionals involved in the care of adults with bronchiectasis, as well as for policymakers, regulatory authorities, and pharmaceutical companies. Bronchiectasis is a complex and heterogeneous disease; therefore, no guideline can be entirely comprehensive or replace clinical judgement. All guideline recommendations must be interpreted within the specific clinical context in which they are applied. Separate ERS guidelines for the management of bronchiectasis in children exist [2]. Bronchiectasis due to cystic fibrosis (CF) has a distinct evidence base; therefore, guidance for the management of CF is provided elsewhere. [3] Some bronchiectasis-associated conditions also have distinct guidelines for investigation and management, such as primary ciliary dyskinesia (PCD) [4], allergic bronchopulmonary aspergillosis (ABPA) [5] and non-tuberculous mycobacterial (NTM) pulmonary disease [6]. While the present guidelines apply for these conditions, they should be interpreted in conjunction with the relevant syndrome-specific recommendations.

๐ŸšจNew 2025 ERS guidelines for the management of adult bronchiectasis! Key update:

Recommend offering longโ€‘term inhaled antibiotics to patients at high risk of exacerbations and with chronic Pseudomonas aeruginosa infection despite standard care.

publications.ersnet.org/content/erj/...

12.11.2025 21:54 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Telacebec, a Potent Agent in the Fight against Tuberculosis: Findings from a Randomized, Phase 2 Clinical Trial and Beyond | American Journal of Respiratory and Critical Care Medicine

๐Ÿ’ซIn this randomized, phase 2 clinical trial, telacebec demonstrated antimycobacterial activity over 14 days in patients with smear-positive pulmonary TB. #AJRCCM

doi.org/10.1164/rccm...

10.11.2025 19:41 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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โฐOnly a few hours left to submit abstracts and case reports for #ATS2026! โฐ

The ATS is accepting scientific abstracts and case reports on all aspects of respiratory disease, critical care, and sleep medicine for ATS 2026.

Deadline is 5 p.m. ET, Nov. 5, 2025: conference.thoracic.org/program/call...

05.11.2025 15:00 โ€” ๐Ÿ‘ 3    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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New #IDSAGuidelines! IDSA has released updated evidence-based recommendations on administering age-appropriate Influenza and RSV vaccinations in populations with compromised immunity. https://www.idsociety.org/Seasonal-RTI-Vaccinations-in-Immunocompromised-Patients/

04.11.2025 22:13 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 6
European Respiratory Society Clinical Practice Guideline for the Management of Adult Bronchiectasis BackgroundBronchiectasis is a common lung condition associated with wide range of infectious, immunological, autoimmune, allergic and genetic conditions. Exacerbations and daily symptoms have the largest impact on patients and healthcare systems, and they are the key focus of treatments. Current practice is heterogeneous globally, and bronchiectasis has historically been a neglected disease. Here, we present evidence-based international guidelines for the management of adults with bronchiectasis.MethodsA European Respiratory Society (ERS) Task Force, comprising global experts, a methodologist, and patient representatives, developed clinical practice guidelines in accordance with ERS methodology and the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) approach. Systematic literature searches, data extraction, and meta-analysis were performed to generate evidence tables, and recommendations were formulated using the evidence-to-decision framework. A total of 8 PICO (Patient, Intervention, Comparator, Outcomes) questions and 3 narrative questions were developed.RecommendationsThe Task Force recommendations include strong recommendations in favour of airway clearance techniques for most patients with bronchiectasis and pulmonary rehabilitation for those with impaired exercise capacity. We issue a strong recommendation for the use of long-term macrolide treatment for patients at high risk of exacerbations and a strong recommendation in favour of long-term inhaled antibiotics in patients with chronic Pseudomonas aeruginosa infection at high risk of exacerbation. Conditional recommendations support the use of eradication treatment or mucoactive drugs in specific circumstances. We suggest not to routinely use long term oral, non-macrolide antibiotic treatment or inhaled corticosteroids. Additional guidance is also provided on testing for underlying causes, managing exacerbations, and managing the deteriorating patient.ConclusionThe ERS bronchiectasis guidelines provide an evidence-based framework for optimal management of adults with bronchiectasis and serve as a benchmark for evaluating the quality of care.Scope and objectivesThe European Respiratory Society (ERS) guidelines for the management of bronchiectasis in adults provide evidence-based recommendations for the care of people with clinically significant bronchiectasis, defined by the presence of permanent dilatation of the bronchi evident on chest CT scan, along with characteristic clinical symptoms. [1] These guidelines are intended for all healthcare professionals involved in the care of adults with bronchiectasis, as well as for policymakers, regulatory authorities, and pharmaceutical companies. Bronchiectasis is a complex and heterogeneous disease; therefore, no guideline can be entirely comprehensive or replace clinical judgement. All guideline recommendations must be interpreted within the specific clinical context in which they are applied. Separate ERS guidelines for the management of bronchiectasis in children exist [2]. Bronchiectasis due to cystic fibrosis (CF) has a distinct evidence base; therefore, guidance for the management of CF is provided elsewhere. [3] Some bronchiectasis-associated conditions also have distinct guidelines for investigation and management, such as primary ciliary dyskinesia (PCD) [4], allergic bronchopulmonary aspergillosis (ABPA) [5] and non-tuberculous mycobacterial (NTM) pulmonary disease [6]. While the present guidelines apply for these conditions, they should be interpreted in conjunction with the relevant syndrome-specific recommendations.

๐Ÿ”ฅ๐Ÿ”ฅ๐Ÿ”ฅ Hot of the press: European Respiratory Society Clinical Practice Guideline for the Management of Adult Bronchiectasis publications.ersnet.org/content/erj/... #Bronchiectasis @atscommunity.bsky.social @btsrespiratory.bsky.social

03.11.2025 23:05 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐ŸงชMeet our @ATS_PITB Assembly Early Career Highlight, Dr. Kevin Guzman!๐Ÿ”ฌ Dr. Guzman is working to improve outcomes in people living with HIV and TB. ๐Ÿงซ

24.10.2025 14:58 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Disparities in Nontuberculous Mycobacteria Mortality in the United States, 1999-2020 | American Journal of Respiratory and Critical Care Medicine | Articles in Press Click to see any corrections or updates and to confirm this is the authentic version of record

โœจ Published in AJRCCM: A comprehensive analysis of NTM-related mortality in the US reveals a rise over the past two decades, with notable disparities across age, race, gender, and geography.

www.atsjournals.org/doi/epdf/10....

15.10.2025 13:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
The Effectiveness of Isoniazid Preventive Treatment among Contacts of Multidrug-Resistant Tuberculosis: A Systematic Review and Individual-Participant Meta-Analysis | American Journal of Respiratory and Critical Care Medicine | Articles in Press Click to see any corrections or updates and to confirm this is the authentic version of record

Recently published in AJRCCM: A systematic review and meta-analysis of 6,668 household contacts of MDR-TB found that isoniazid was effective in preventing incident TB, particularly in high-burden countries.
#TB #globalhealth #StopTB

www.atsjournals.org/doi/epdf/10....

13.10.2025 21:08 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Presenter: Mansi Chaturvedi, MD (Univ. of Maryland/NIH)
Moderator: Jerry Zifodya, MD, MPH, TM (Tulane)
Experts: Celso Khosa, PhD (Instituto Nacional de Saรบde) & Brian Allwood, MD (Stellenbosch Univ/Tygerberg Hospital, South Africa)

26.09.2025 19:16 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ”ฅMark your calendars!๐Ÿ”ฅ
@ats-pitb.bsky.social is hosting a๐ŸŒฒPINE๐ŸŒฒWebinar on Post-TB Lung Disease ๐Ÿซ
Case-based discussion, diagnosis & treatment with ๐ŸŒ global experts!
๐Ÿ“… Tue Oct 28 10AM ET
๐Ÿ—’๏ธRegister Here: bit.ly/47X6auu
#TB @atscommunity.bsky.social @theunion.org @btsrespiratory.bsky.social

26.09.2025 19:16 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Great honor to welcome Dr. Charles Dela Cruz, past @ats-pitb.bsky.social Chair, to @tulanemedicine.bsky.social today! He is giving an outstanding talk on COVID-19 and interferonsโ€”sharing deep insights into pathogenesis and host responses. #COVID19 #Interferons #ATS

24.09.2025 17:37 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Bedaquiline, delamanid, linezolid, and clofazimine for rifampicin-resistant and fluoroquinolone-resistant tuberculosis (endTB-Q): an open-label, multicentre, stratified, non-inferiority, randomised, c... The shortened BDLC strategy was not non-inferior to the control. Accumulating evidence suggests that this patient population might require longer, reinforced regimens.

Bedaquiline, delamanid, linezolid, and clofazimine for rifampicin-resistant and fluoroquinolone-resistant tuberculosis (endTB-Q): an open-label, multicentre, stratified, non-inferiority, randomised, controlled, phase 3 trial - The Lancet Respiratory Medicine www.thelancet.com/journals/lan...

24.09.2025 17:20 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Research Priorities for Noninvasive Sampling of the Lower Respiratory Tract during Acute Respiratory Failure: An Official American Thoracic Society Workshop Report | Annals of the American Thoracic Society

๐Ÿšจ ATS Workshop Report on non-invasive sampling of the lower respiratory tract: Experts highlight how to tailor your testing and make non-invasive testing fast, reproducible, and scalable. #PulmCCM #ATSworkshop buff.ly/i2qobaA

01.09.2025 02:36 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline | American Journal of Respiratory and Critical Care Medicine | Articles in P...

๐Ÿšจ New 2025 ATS guidelines on community-acquired pneumonia! Key change:

Empiric antibiotics are suggested for adults hospitalized with clinical and imaging evidence of CAPโ€”whether non-severe or severeโ€”who test positive for a respiratory virus.

doi.org/10.1164/rccm...

29.08.2025 18:05 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ“ฃCalling all assembly members!๐Ÿ“ฃ Help shape the future of the ATS by nominating a colleague for a leadership position within your assembly. We're accepting nominations for a variety of positions!

Submit your nominations before Sept. 4! surveymonkey.com/r/YHQFMGZ

28.08.2025 12:46 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis | NEJM In bronchiectasis, neutrophilic inflammation is associated with an increased risk of exacerbations and disease progression. Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1 (DPP...

๐ŸŒŸ Brensocatib: first FDA-approved therapy for bronchiectasis. Key takeaways!

First DPP-1 inhibitor for non-CF bronchiectasis & neutrophil-mediated disease.

Effective across key subgroups: macrolide users, varying eosinophil counts, adolescents.

www.nejm.org/doi/full/10....

27.08.2025 17:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline | American Journal of Respiratory and Critical Care Medicine | Articles in P...

๐Ÿšจ New 2025 ATS guidelines on community-acquired pneumonia! Key points:

For stable adults with outpatient CAP, <5 days of antibiotics are recommended (minimum duration: 3 days).

Systemic corticosteroids for adults hospitalized with severe CAP.

doi.org/10.1164/rccm...

26.08.2025 17:03 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Efficacy and Safety of Higher Doses of Levofloxacin for Multidrug-resistant Tuberculosis: A Randomized, Placebo-controlled Phase II Clinical Trial | American Journal of Respiratory and Critical Care M...

AJRCCM: Results from a randomized, placebo-controlled Phase II clinical trial evaluating the optimal dose, acceptable safety, and tolerability of levofloxacin as part of a multidrug TB regimen.

doi.org/10.1164/rccm...

25.08.2025 18:58 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline | American Journal of Respiratory and Critical Care Medicine | Articles in P...

๐Ÿšจ New 2025 ATS guidelines on community-acquired pneumonia! Key changes:

Lung ultrasound now an evidence-based alternative to chest X-ray for diagnosis

No antibiotics for outpatients with no comorbidities and a positive viral test

doi.org/10.1164/rccm...

22.08.2025 14:08 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@ats-pitb is following 20 prominent accounts