ATS PITB Assembly

www.atsjournals.org/doi/abs/10.1...
✨NEW✨ATS Guidelines for Community-Acquired Pneumonia-addresses lung ultrasound for diagnosis, empiric antibacterial therapy if a test for a respiratory virus is positive, antibiotic duration, and the use of systemic corticosteroids.

Psychological stress and health-related quality of life among tuberculosis patients: a prospective cohort study Economic, social and psychological distress is common in individuals affected by tuberculosis (TB). However, the magnitude of distress, psychological interventions and their effect on the treatment outcomes are often under-evaluated. We examined the level of psychological stress and health-related quality of life (HRQoL) of such patients and the effect of antituberculosis therapy on them. Our prospective cohort study included newly diagnosed adult pulmonary and extrapulmonary TB patients. Assessment of psychological stress was done using the seven-item Generalised Anxiety Disorder questionnaire for anxiety and the nine-item Patient Health Questionnaire for depression. HRQoL was assessed by using the WHOQOL-BREF questionnaire. Of the 86 patients studied, 21 (24.4%) had anxiety symptoms at the baseline, which reduced to 5.8% and 1.2% at 2 months and treatment completion, respectively (p<0.001). Among the subjects, 18 (20.9%) patients had depression, which reduced to 7% and 2.3% at 2 months and treatment completion, respectively (p<0.001). All the mean domain scores of HRQoL were poor at the baseline, which showed improvement at treatment completion (p<0.001). Anxiety and depression were common among TB patients, and there was significant progressive reduction during and after treatment. TB had remarkable negative impacts on HRQoL, with the physical domain being the most affected, and all the domain scores showed significant improvement at treatment completion. Routine screening for depression and anxiety and timely referral to a psychiatrist are required in TB patients to improve the outcome of the disease and quality of life.

publications.ersnet.org/content/erjo...
TB has negative impacts on health-related quality of life-e.g., anxiety and depression are common in people with TB. Consider routine screening for depression and anxiety, with referral to psychiatry if necessary, to improve disease outcomes and QOL.

Evaluation and Comparison of Multiple Test Methods, Including Real-time PCR, for Legionella Detection in Clinical Specimens Legionella is a Gram-negative bacterium that can cause Pontiac fever, a mild upper respiratory infection and Legionnaire’s disease, a more severe illness. We aimed to compare the performance of urine ...

pmc.ncbi.nlm.nih.gov/articles/PMC...
Practice alert! Providers should submit sputum in addition to urinary antigen testing when diagnosing legionella pneumonia.

Target Trial Emulation of Empiric Antibiotics on Clinical Outcomes in Moderately Immunocompromised Patients Hospitalized with Pneumonia - PubMed Immunocompromised patients hospitalized with pneumonia often receive empiric broad-spectrum antibiotics despite low rates of multidrug-resistant organisms. Empiric broad-spectrum antibiotic use was no...

pubmed.ncbi.nlm.nih.gov/40601818/
Empiric broad-spectrum abx use in moderately immunocompromised patients with CAP not associated with mortality, but was associated with harm (30-day readmission, transfer to ICU, longer duration of hospitalization).

📢📢📢 Don't miss the excellent webinar from our pediatric ATS colleagues on the important topic of pediatric TB! Info below. #STOPTB

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@ATSPeds VIPPN case series on Challenges in Diagnosis of Childhood Tuberculosis in Low Resource Settings
August 7th at 1pm ET
Register here: shorturl.at/Gyqop

Respiratory viral infections awaken metastatic breast cancer cells in lungs - Nature Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by epidemiological d...

www.nature.com/articles/s41...
Murine model shows how influenza and SARS-CoV-2 infections lead to loss of the pro-dormancy phenotype in breast dormant disseminated cancer cells in the lung, causing proliferation & expansion of carcinoma cells into metastatic lesions within 2 weeks.

Dynamic 11C–Para–Aminobenzoic Acid Positron Emission Tomography/Computed Tomography for Visualizing Pulmonary Mycobacteroides abscessus Infections | American Journal of Respiratory and Critical Care Medicine www.atsjournals.org/doi/full/10....

🔥Excellent discussion during the ATS PINE Webinar with Dr. Saukkonen and Dr. Daley on 2025 TB treatment guideline updates. Please share your questions and thoughts with us here, on X or LinkedIn in the ATS_PITB feed! #STOPTB

@idsainfo.bsky.social @btsrespiratory.bsky.social @theunion.org

🌲 COMING UP THIS MONDAY🌲
🚨 Don’t miss the PINE Webinar on the NEW TB treatment guidelines!
🦠 Big updates. Expert insights. Sign up today!
#TB #GlobalHealth #MedSky #PCCMSky
@ats-assemblies.bsky.social @idsainfo.bsky.social @btsrespiratory.bsky.social @theunion.org

New in AJRCCM: The first comprehensive plasma proteome map of community-acquired pneumonia reveals key proteins linked to disease severity, multi-organ involvement, and 10-year pneumonia risk. Findings pave the way for biomarker-driven precision medicine in respiratory infections. buff.ly/kPgq5FM

Combining tuberculin skin test with follow-on interferon gamma release assay markedly improves screening of household contacts Introduction In Hong Kong, tuberculin skin test (TST) with a 15 mm cut-off was used at 0 and 3 months for contact screening, but half of future tuberculosis cases might be missed. Follow-on…

New in Thorax: Adding follow-on IGRA to TST (5–14 mm) for household TB contacts in Hong Kong boosted detection, cut missed cases, and reduced overtreatment. Serial testing at 0 & 3 months captured 96% of future TB cases with fewer false positives.
buff.ly/pw1BA3b

Strategies for shortening tuberculosis therapy - Nature Medicine Insights into TB heterogeneity are informing strategies for patient stratification and treatment shortening; this Perspective discusses the formidable challenge of treating this complex disease with…

Rethinking TB treatment duration. This Perspective argues for patient stratification and innovative regimens to safely shorten therapy, reduce overtreatment, and tackle drug resistance.

Want to learn more about our🌲PINE🌲 Webinars? Check out this article in the British Respiratory Society’s Respiratory Futures magazine: bit.ly/4lrKSZl

Also, don’t miss this @btsrespiratory.bsky.social webinar on CF next month: bit.ly/4lxcgVT

#STOPTB
@atscommunity.bsky.social

Presenter: Dr. Lahari Tumuluri (Tulane)

Experts:
Dr. Charles Daly (National Jewish)
Dr. Jussi Saukkonen (Boston University)

Moderator: Dr. Eva Otoupalova (Tulane)

Full guidelines here: bit.ly/449D492

🔥 !COMING SOON! 🔥 Drs. Saukkonen & Daly will unpack the 2025 ATS/CDC/ERS/IDSA TB guidelines in this newest🌲PINE🌲 webinar!

📅 July 21 | 12 PM ET
🔗 Register here: bit.ly/446PvCv

@atscommunity.bsky.social
@ats-assemblies.bsky.social
@idsainfo.bsky.social
@theunion.org
@btsrespiratory.bsky.social

🧬TB doesn’t end with treatment. New US study reveals life expectancy after TB diagnosis was 2 years shorter for TB cohort compared to non-TB cohort. We need to rethink what “cured” really means. 📉🫁 #Tuberculosis #PublicHealth

www.atsjournals.org/doi/full/10....

Great PITB session on pulmonary viral infections across lifespan! More exciting sessions to come! #ATS2025

3 bottle system of pleural drainage in real time! Join the #ATS2025 Teaching Competition in the Marriott J right now!

🔥Happening now: ATS Teaching Competition at Marriott Pacific J (4th floor). Join us for some excellent education!!! #ATS2025
@atscommunity.bsky.social @ats-assemblies.bsky.social

Happening now: Charles Dela Cruz talking about predisposition to COPD and viral infections. Join us at Moscone West 2001 #ATS2025 @atscommunity.bsky.social @ats-assemblies.bsky.social

♨️♨️♨️ Don't miss out!! Join us at Moscone West Room 2001/2003 for Symposium on Pulmonary Virus Infections Across the Lifespan. Discover latest science on host-virus interaction!

Session info here: ats2025.d365.events/directory/se...

#ATS2025 @atscommunity.bsky.social @ats-assemblies.bsky.social

Congratulations to the ATS PITB 🌟🌟🌟Peer Recognition Awardees 🌟🌟🌟 Dr. Katrina Traber (Early Career), Dr. Barbara Jones (Mid Career) and Dr. Kristina Crothers (Senior-Level Peer Recognition)! What an inspiring group!
#ATS2025 @atscommunity.bsky.social @ats-assemblies.bsky.social

Congratulations to our PITB🌟🌟🌟RISING STARS🌟🌟🌟 Dr. Merete Long and Dr Taylor David Coston!! #ATS2025
@atscommunity.bsky.social @ats-assemblies.bsky.social @atsearlycareer.bsky.social

Congratulations to PITB Abstract Awardees!#ATS2025

Happening now: PITB Assembly Meeting! Join us at Moscone West Room 3000! #ATS2025

📢📢📢Join us for the ATS PITB Assembly Membership Meeting tonight 5 - 7 p.m. at the Moscone Center Room 3000/3002/3004 (West Building, Level 3)! #ATS2025

Happening now: Join us at Moscone South Room 209-211 to learn about host directed therapies! #ATS2025 @atscommunity.bsky.social @ats-assemblies.bsky.social

#ATS2025 is here!!! Looking forward to many exciting
Pulmonary Infections and Tuberculosis sessions! Check out our 🗞️Newsletter🗞️ to find a full list of PITB sessions!

@ats-assemblies.bsky.social @atscommunity.bsky.social

Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis - Nature Medicine A novel personalized phage therapy strategy that selects phages for a predicted evolutionary trade-off may represent a viable alternative approach for the treatment of antimicrobial-resistant bacteria...

♨️♨️♨️ Hot of the press: Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis

www.nature.com/articles/s41...

🔥 🔥 🔥 Hot of the press: Broad Immunomodulatory Effects of the Dipeptidyl Peptidase-1 Inhibitor Brensocatib in Bronchiectasis: Data from the Phase 2, Double-Blind, Placebo-controlled WILLOW Trial

Article here: buff.ly/2HsFkW7

Related editorial here: buff.ly/fHEPmaY