Lucía de Hoyos

Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity - npj Science of Learning npj Science of Learning - Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity

Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity. New paper by @luciadehoyos.bsky.social & al. with Ellen Verhoef, @profsimonfisher.bsky.social , @bstpourcain.bsky.social
doi.org/10.1038/s41539-025-00329-y

The shared genetic architecture and evolution of human language and musical rhythm - Nature Human Behaviour Using a battery of statistical tools, Alagöz et al. examine the genetic overlap between dyslexia and rhythm impairment and shed light on how the genome influences the neural bases of human language an...

Our paper out today in @naturehumbehav.bsky.social integrates data from large-scale genome scans of dyslexia & rhythm skills, as a novel way to investigate biological overlaps between human traits related to language & musicality. Co-led by Reyna Gordon (Vanderbilt). 🧪
www.nature.com/articles/s41...

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I had a chat with Eiko Fried about a new GWAS of Depression in 685.000 cases and 4.3 million controls... That's like all of Denmark? Here is the GWAS: https:... is this an accidental Podcast? Eiko Fried & Michel Nivard discuss a new GWAS of depression preprint

I have been (foolishly?) searching for peak 2015-2017 twitter "science on socials" magic... In an experiment to recapture that excitement, I talked to @eikofried.bsky.social , in what might veer into podcast territory(?), about a new GWAS of Depression (N > 5 million) www.youtube.com/watch?v=vHvB...

The chromatin remodeler CHD3 is highly expressed in mature neurons and regulates genes involved in synaptic development and function bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

And there you have it! #ExInPlotter, an easy-to-use online tool for plotting your genes of interest. Here applied in our latest CHD3 pre-print on bioRxiv (den Hoed et al). biorxiv.org/content/10.1...
@joerydh.bsky.social

Do you want to also plot additional custom sequences? (e.g. guideRNA, probes...) 🚩You can do that too! We provide an example file for this.

How does it work? ⚙️
1️⃣ Select the genome build (e.g. Human-hg38)
2️⃣ Write down the gene you want to visualise (e.g. CHD3)
3️⃣ Select as many transcripts as you would like to plot
4️⃣ Adapt the scale bar (in case your gene is bigger/smaller than the default one)
5️⃣ Export it as pdf

Looking for an online tool to plot your gene of interest? @joerydh.bsky.social and I have created #ExInPlotter. A shiny app where you can select a genome build (also non-human ones) and plot your gene(s) of interest.
Check it out here: jho2024.shinyapps.io/ExInPlotter/

A new publication from the EAGLE consortium: Genome-wide Analyses of Vocabulary Size in Infancy and Toddlerhood:
www.biologicalpsychiatryjournal.com/article/S000...
with summary statistics deposited here: t.co/5f0SFNf0mb

Distinct genetic pathways to music enjoyment bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

What makes us so susceptible to the power of music?

Our new pre-printed work suggests that genetic variation, primarily dissociated from other relevant perceptual-affective processes, also seems to be at play.

www.biorxiv.org/content/10.1...

But the story does not end here ...

Structural models of genome-wide covariance identify multiple common dimensions in autism - Nature Communications Studying individuals with autism only, this study investigated the genomic architecture of autism-related phenotypes using a multivariate modelling framework. This work identified distinct genomic fac...

🚨Our study "Structural models of genome-wide covariance identify multiple common dimensions in autism", where we disentangle phenotypic heterogeneity in ASD from a genetic perspective, is out now in Nature Communications
➡️ nature.com/articles/s41...
@bstpourcain.bsky.social @simonsfoundation.org