PREDICT

What a pleasure to participate in #ECCO26! 🎉

We were happy to contribute with talks, oral presentations of abstracts, and poster presentations. Associate Professor @sazonovs.bsky.social received the Young Researcher Award 2026 and Assistant Professor Filip Ottosson received the ECCO Grant.

@dg.dk

For an overview of our presentations, see www.predictibd.dk/meet-predict...

We are widely represented at ECCO’26 Congress, providing a number of presentations, talks, and poster presentations. We are looking very much forward to participating in the transformative discussions on how, together, we can improve holistic care for the millions living with IBD worldwide. See you!

After five months, we are now saying goodbye to Mical Woldu 🇮🇹 During her internship, she carried out a nationwide Danish cohort study to see whether IBD clusters within families affects the development of IBD — helping to highlight the role of environmental factors alongside genetics

@dg.dk @aau.dk

New study in Gastroenterology shows that increased aggregated genetic risk of IBD is associated with a more severe disease course, as measured by inflammatory markers, medication need, hospitalizations, and gastrointestinal surgeries.

👉 www.sciencedirect.com/science/arti...

@dg.dk @aau.dk

👉 www.nature.com/articles/s41...

Authors 🖋️
Marie Vibeke Vestergaard
Alonzo Alfaro-Núñez
@sazonovs.bsky.social
Georgios Athanasiadis
Tine Jess

@dg.dk @aau.dk @aalborguh.rn.dk

Though often co-studied, our latest study reveals that Crohn’s Disease and ulcerative colitis harbor distinct genealogical, genetic, and microbial associations with a broad spectrum of immune-mediated inflammatory diseases (IMIDs).

See all disease profiles in Nature Communications. Link in Comments

🩺Behandling med #statiner kan mindske risiko for at udvikle sygdomme som #Crohns sygdom og #colitis ulcerosa 👉Studie fra DG-center
@predictibd.bsky.social 👇
medicinsktidsskrift.dk/behandlinger...

It has been a fruitful day for our OPTICS group meeting with collaborators across disciplines and from around the world, ambitiously aiming to elucidate the role of microplastics as risk factors of IBD, specifically regarding the yet unexplained segmental intestinal inflammation of Crohn’s disease.

Authors
Anders Mark-Christensen
Anthony Charles Ebert
Gry Juul Poulsen
Søren Laurberg
Jens Fuglsang
Tine Jess
Mette Julsgaard

@dg.dk @aau.dk @aalborguh.rn.dk

Laparoscopic surgery is generally believed to have a lower risk of adverse pregnancy and birth outcomes than open surgery. However, in our new study of women with IBD who had undergone abdominal surgery, we found no difference in outcomes based on surgery approach

👉 academic.oup.com/ecco-jcc/adv...

Nordjyder får færrest lyse timer om vinteren: Ekspert peger på tre råd, der gør en forskel Mindre dagslys giver udfordringer for både krop og sind. Her er ekspertens tre bedste bud på, hvordan du håndterer det.

☀️Manglen på sollys i vinterhalvåret kan have konsekvenser for sundheden. Både på den korte og lange bane. Centerleder Tine Jess, @predictibd.bsky.social, forklarer hvorfor og giver tre gode råd👇
nordjyske.dk/nyheder/nord...

Authors 🖊️
Jonas J. Rudbæk
Adam Koziol
Alice Fracchia
Madeleine Ernst
Aleksejs Sazonovs
Martin Woergaard Kjær
Nis Borbye-Lorenzen
Kristin Skogstrand
Tine Jess
Filip Ottosson

@dg.dk @aau.dk @aalborguh.rn.dk @ssi-dk.bsky.social

For the first time globally, we have observed changes in the newborn metabolome of individuals who later develop IBD. Our study has just been published in Gastroenterology and establishes a foundation for future research into early metabolic alterations in IBD.

www.sciencedirect.com/science/arti...

Our latest study is out! 📊 We’ve uncovered 8 reproducible patterns of FC and CRP in #IBD, moving us closer to individual patient prognostication.
Developed by our team and validated in Denmark with @predictibd.bsky.social 🏴󠁧󠁢󠁳󠁣󠁴󠁿🤝🇩🇰
Pre-proof in @CGHJournal: www.cghjournal.org/article/S154...

Authors 🖊️
Olivia Mariella Anneberg
Sjurdur Frodi Olsen
Anne Vinkel Hansen
Mette Julsgaard
Anne Ahrendt Bjerregaard
Thorhallur Ingi Halldorsson
Tine Jess
Maiara Brusco De Freitas

@dg.dk @aau.dk @aalborguh.rn.dk @ssi-dk.bsky.social

Our study on maternal intake during pregnancy suggests that adhering to a diverse dietary pattern with a broad intake of various food groups may protect against IBD in offspring. This finding may be key in future preventive strategies targeting early risk factors.

👉 www.nature.com/articles/s43...

Authors
Nathan Constantine-Cooke
Marie Vibeke Vestergaard
Nikolas Plevris
Karla Monterrubio-Gómez
Clara Ramos Belinchón
Solomon Ong
Alexander T. Elford
Beatriz Gros
Aleksejs Sazonovs
Gareth-Rhys Jones
Tine Jess
Catalina A. Vallejos
Charlie W. Lees

@dg.dk @aau.dk @aalborguh.rn.dk

Better monitoring of patients with IBD. That is the aim of our new study exploring inflammatory trajectories of patients with IBD. The study has been carried out at the initiative of @edinburgh-uni.bsky.social and just been published in @aga-cgh.bsky.social.

www.sciencedirect.com/science/arti...

HAPPY HOLIDAYS TO ALL OF YOU FROM ALL OF US AT PREDICT 🌲
 
A special thank you to all our collaborators, national and international across scientific disciplines, for a great year with wonderful interactions and great achievements. 
 
We look forward to continuous and new collaborations in 2026 💜

Authors 🖊️
Alonzo Alfaro-Núñez
Stina Christensen
Jette Ellehauge
Jens Ole Eriksen
Gitte Andersen
Esther A. Jensen

@dg.dk @aau.dk

Human faecal samples can be used for the early detection and characterization of colorectal cancer and has a much lower error ratio, cost and less discomfort to patients than colonoscopy. That is one of the most interesting findings in our new study ➡️ www.nature.com/articles/s41...

Center Director Tine Jess has participated in the 2. European Science Diplomacy Conference. In line with the key messages of the conference, PREDICT has a particular focus on extending our core collaborations from leading institutions in Europe and the US to stakeholders in the Global South.

@dg.dk

Very pleasant visit today at PREDICT by our Research Associate Adam Faye to celebrate a recent shared publication.

@dg.dk @aau.dk @aalborguh.rn.dk

Patients with chronic pouchitis can be identified based on antibiotic use after an initial episode of pouchitis. Our new study has just been published in AJG. It suggests the need for improved risk stratification at the time of IPAA surgery.

journals.lww.com/ajg/abstract...

@dg.dk @aau.dk

A heartfelt thank you to the Women in IBD EU Focus Meeting. This year, PREDICT had the pleasure of joining the meeting, participating in discussions, and delivering two talks on the global epidemiology of IBD, and the monitoring of disease activity during pregnancy and postpartum.

@aau.dk @dg.dk

Diversity! We had the privilege of hosting the annual site visit of @dg.dk, inviting us to provide our view on risk-taking in the context of Centers of Excellence. Our answer: Working together across scientific fields and global cultures for us is a path to original thinking and breakthroughs.

Authors 🖊️
Henrik Albaek Jacobsen
Christina Faaborg Larimore
Christian Graugaard
Mikael Andersson
Lone Larsen
Morten Frisch

@dg.dk @aau.dk @aalborguh.rn.dk

The largest population-based study on sexual dysfunction among patients with IBD using the Danish SEXUS cohort has just been published in the Inflammatory Bowel Disease journal.

Our results indicate need for incorporation of sexual health in IBD care.

➡️ doi.org/10.1093/ibd/...

Authors 🖊️
Adam Faye
Kristine Højgaard Allin
Gry Juul Poulsen
Tine Jess

@dg.dk @aau.dk @aalborguh.rn.dk