Michael Miles

Michael Miles

@rnaguy.bsky.social

Family guy. Love outdoors, music, dancing, astronomy, alcohol and addiction research, neuroscience, genomics, training students. Comments are personal opinions only.

537 Followers 397 Following 188 Posts Joined Nov 2024
1 week ago
Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success.

Data source: https://report.nih.gov/nihdatabook/report/302

The data is in: the NIH goalposts have shifted.

What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards.

Another manifestation of how HHS policies have led to fewer awards and less science.

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1 week ago
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🎯🎯

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1 week ago
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MASSIE: “Iran is not Venezuela. The Ayatollah was not a president. He was a religious leader… 🇺🇸 & 🇮🇱 turned him into a martyr, expended billions, 6 🇺🇸 families must now lay to rest their sons & daughters. And for what? This administration can't even give us a straight answer.”

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1 week ago

He doesn’t care that gas prices are up and jobs down. He doesn’t care that American citizens were killed in our streets by his stormtroopers. If American soldiers and innocent children are killed in his useless evil war — “it happens”. This disgusting little man will live in infamy.

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1 week ago
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Obama: "We are living in a time where it can be hard to hope. Each day we wake up to some new assault on our democratic institutions. Another setback to the idea of the rule of law ... but this man - Rev. Jesse Jackson - inspires us to take a harder path ... bc if we don't step up, nobody else will"

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1 week ago

DHS nominee Markwayne Mullin is one of the most active stock-traders in the Senate — and violated the STOCK Act against insider trading as recently as last August.

He currently holds stock in L3Harris, which has millions in contracts with ICE and FEMA.

The grift continues.

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1 week ago
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We can throw another $500,000,000,000 at the Pentagon this year and spend $1,000,000,000/day on a wholly useless war, but we can't afford to hire doctors and nurses to take care of our veterans? The United States is such an irresponsible, messed up country right now.

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3 weeks ago
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This is the interview Donald Trump didn’t want you to see.

His FCC refused to air my interview with Stephen Colbert.

Trump is worried we’re about to flip Texas.

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3 weeks ago
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We are the laughing stock of the world.

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3 weeks ago
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👀👆

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3 weeks ago
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More of this, please. The folks in this grassroots group are heroes.

Haven Watch lives by the promise, “No One Walks Alone.” Day or night, they show up. When people are released from ICE detention, volunteers meet them in the cold, disoriented, and exhausted.

Beautiful and devastating all at once.

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1 month ago
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SHABOOZEY: “Immigrants built this country.”

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1 month ago
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1 month ago

Brutal week. But besides the politics — temps below freezing for a week with lows in single digits freezing the 6 inches of snow/sleet/freezing rain from last weekend. We now have 2-4” of solid ice. An 1100 pound horse can walk across it without breaking through and our driveway is impassable!

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1 month ago
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IMMORAL…

This drawing was made by one of the 5 year old El Gamal twins. It shows children behind bars with the caption, “I’m 5 years old.”

An immigration judge denied them bond, citing “insufficient assets.” These children could remain in detention for years while their case is appealed.

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1 month ago

They also need warrants before breaking down doors and to stop brutally assaulting people on the street (much less killing them!). They need IDs and to remove face masks. People arrested need due process. Right now ICE is nothing but Trump's (Miller's) gestapo. This is not (just) about immigration.

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1 month ago
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Snapshot: Monsters in Our Midst They are not just indifferent to a deadly shooting, they revel in it. But their terror is triggering a rising tide of anger and resistance.

“People like this do not belong on our streets. They should not be permitted to carry deadly weapons. They should not be masked, wearing military-style uniforms or hide without badges identifying who they are. They must be held accountable for their crimes.”

www.americaamerica.news/p/snapshot-m...

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1 month ago

Maybe if Denmark put a large tariff on the U.S. for Ozempic, enough people would be upset to stop Trump?

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1 month ago

MAGA has a new meaning — with Europeans providing a vivid reminder of what Trump has done to our allies’ opinion of the U.S. — red baseball caps that say “Make America Go Away”. What a disgusting excuse of a president.

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1 month ago
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1 month ago
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ICE illegally grab a city snow plow driver: "He was detained because of his country of origin. He had every federal authorization. We do a criminal background check of all federal documents."

Sent 1,000 miles to Texas with a serious medical condition. (From Fox 9)

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1 month ago
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people.com/nj-girl-foun...

"6 years old... walking by herself on the street, crying, crying out for her dad, asking, 'Where's Papi? Where's Papi?'..."

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1 month ago

Pew Research Institute (2023):

• Red State Texas has about 2.1 million undocumented immigrants

• Red State Florida has 1.6 M undocumented immigrants

• Blue State Minnesota has 130,000.

And yet only Minnesota is being occupied by masked thugs over "immigration."

It's *not* about immigration.

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1 month ago

Dr. King changed my life. His death and the firm morality of my parents, changed me from a 14 yo near-racist to someone who cares deeply about others. It was a reason I became a physician serving indigent care clinics. He and the Memphis sanitation workers taught me the true meaning of “I am a man”.

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1 month ago

Exactly right. The House and Senate need to be a viable 3rd branch of our democracy. Stop the lunacy. Articles in multiple news sources document that Trump is trying to blackmail Europe because he didn’t get a Nobel prize. This will directly harm American citizens when Europe rightfully responds.

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1 month ago
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Thank you, Minnesota There is no greater obligation for an American than loyalty to the Constitution of the United States.

Thank you, Minnesota
open.substack.com/pub/stevesch...

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2 months ago

Honorable people resigned rather than participating in the absolute coverup of this crime. That is the kind of courage it will take to prevent DOJ and the White House from getting away with this.

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2 months ago
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2 months ago
Sign on door prohibiting immigration enforcement on private property Shelf filled with goggles and whistles

This is Minneapolis:

Walk into my neighborhood ACE last night & see the signage on their door notifying fed agents that it’s private property and cannot be used for immigration enforcement. These signs are all over the city.

Walk in & the nearest shelf has goggles & whistles.

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2 months ago

White House said Trump’s actions were justified.What a “president”. Lies more than anyone, denigrates a woman murdered by his storm troopers, dictates the illegal arrest of American citizens, cares for no one but himself and makes obscene gestures at his citizens. The last action speaks mountains.

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