Sam Golden

YouTube video by UC Davis From Labs to Lives: Brian Trainor, Ph.D.

I made a video with @ucdavis.bsky.social on the benefits of federal grants for health science and our economy. Please share with friends/family that could be receptive or better yet, make your own video www.youtube.com/watch?v=ndjH...

Join our department! NBIO is hiring an Assistant Teaching Professor. Position open until April 1, 2025. Please share with your networks. Apply @ apply.interfolio.com/162469 #stemhiring #neurojobs

The @uw-nbio.bsky.social Dept. Neurobiology & Biophysics has job posting for an Assistant Teaching Professor! Open until April 1, 2025.

This position will support the UW undergraduate Neuroscience major, with a focus on ephys labs.

Please share widely!

apply.interfolio.com/162469

Got Bowie on the brain

New NIH R01 grant to examine anatomy and function of the dorsal endopiriform nucleus as part of the claustrum complex. reporter.nih.gov/search/6CHod.... Looking for team members (e.g., postdoc, tech) to join the journey.

Remarkable talk by Dr. Mitra Heshmati today at the Conciousness GRC, on the engineering of synthetic consciousness states through whole brain genetic capture.

Protocol-sharing site aims to ease administrative burden of animal research The library of regulatory-compliant animal procedures offers experimental standards and specific language that researchers can borrow for their own legal paperwork.

Life as a researcher comes with a mountain of paperwork. A new IACUC procedure database aims to lighten the load.

By @callimcflurry.bsky.social

www.thetransmitter.org/community/pr...

New paper out! Led by @michaelecoulter.bsky.social, we learned that rats can learn to use content-specific neurofeedback to generate specific remote hippocampal representations. surprisingly, this occurs *outside* of SWRs!

To all the scientists out there, just keep breathing.

Experience-dependent dopamine modulation of male aggression - Nature Dopaminergic neurons in the ventral tegmental area have a role in modulating aggression in adult male mice, and this effect of dopamine depends strongly on fighting experience.

Antipsychotics is often used to suppress hyper-aggression. Does it really suppress aggression or just cause sedation? Antipsychotics targets dopamine receptors. Our new study revealed that dopamine modulates aggression based on animals' fighting experience.

www.nature.com/articles/s41...

Dietary phytoestrogens recalibrate socioemotional behavior in C57Bl/6J mice in a sex- and timing-dependent manner Estrogens are potent regulators of socioemotional behavior across species. Ubiquitous in human and animal diets, plant-derived phytoestrogens (PE) bin…

New paper from the lab! Do you pay close attention to what your research animals are eating? If you are interested in behavior, development, or reproductive physiology – you should! 🧵 ⬇️ tinyurl.com/yc356mpr

For those of you who say we have taken AI too far, gaze upon this scientifically accurate representation and weep

A novel method for estrous cycle staging using supervised object detection - NPP—Digital Psychiatry and Neuroscience This study presents a new machine learning tool called ODES (Object Detection for Estrous Staging) to determine the estrogen-related cycle stage in female mice. Unlike traditional models that classify...

🆕 in DPN‼️

@rossenator.bsky.social & co @einsteinmededu.bsky.social developed an object detection machine learning tool to identify cell types of the estrous cycle in mice, providing a fast & reliable method for estrous cycle monitoring in neuroscience studies!

www.nature.com/articles/s44...

Excited to share a new tool from the Ross Lab @rossenator.bsky.social @einsteinmededu.bsky.social for estrus staging in mice.
Honored to be part of this innovative work!

John Tuthill explains why practical summer courses in neuroscience matter and how this tradition helps researchers rekindle the unfettered joy that initially brought them to the field.

www.thetransmitter.org/craft-and-ca...

#neuroskyence

Contributions of associative and non-associative learning to the dynamics of defensive ethograms Associative and non-associative learning mechanisms summate to produce robust and complex conditioned behavior profiles, opening new avenues to in-depth investigations of defensive responses and threa...

🚨 New paper alert! 🚨
Excited to share our latest research in @eLife:
We uncover how learning mechanisms shape dynamic defensive behaviors in mice, moving beyond the typical focus on freezing.🧠💡
🔗 Read it here: doi.org/10.7554/eLif...
#Neuroscience #PTSD #FearConditioning

We are excited to announce the first recipient of the DPN Editors’ New Investigator Waiver Award: Dr. Kristin Kostick-Quenet!

The Kostick-Quenet lab focuses on the ethical, social, & cultural factors related to integrating emerging AI-based technologies into clinical care

YouTube video by Sam Golden ArgiNLS in SHIELD cleared sample on LSFM.

youtu.be/4-zZT3BbQOI

Clip from her talk: AAVretro-ArgiNLS-DIO-oScarlet in red, AAV-ArgiNLS-GFP in green (both in the NAc) of a vlgut2-Cre transgenic. Imaged at 1.6x with a SmartSPIM LSFM. Rendered with Arivis.

This is the native (non stained) signal following SHIELD clearing.

Constructs at www.addgene.org/Sam_Golden/

As much fun as ACNP was, thrilled I was able to be back in time to watch Mary Loveless share her rotation presentation with the GPN cohort! Congratulations Mary!

#ACNP2024

Celebrating my bestie’s success at #ACNP2024. So proud for @bangasserlab.bsky.social

Hi #ACNP2024 👋

We are @acnporg.bsky.social’s new open access journal publishing on digital methodologies that advance the diagnosis, treatment, prevention, and modeling of mental illness. We launched just last year and this will be our second ACNP meeting!

Excited for day 1 of #ACNP2024 at the pre-meeting Technology in Psychiatry (TIPS) conference! Fantastic lineup and discussions so far.

A simple one, but we had never tried HA Tag with iDisco+ before. Worked well!

Aww, good to know, Bluesky very noticeably downsamples video apparently, sadness :( Original (small video) way more crispy.

#flourescent(almost)friday
(make sure to full screen this!) Some hippocampal neurons and dendritic arbors visualized from mCherry with a 3.6x objective in a SmartSPIM using iDisco.

Not a big ask at all! Shoot me a DM

Some new images from last night using a new stain (for us). Was imaging with a trainee and we came to the conclusion that being a brain astronaut it pretty cool...

250um MIP from an iDisco cleared brain using LSFM.