International Cell Senescence Association

The General Assembly closed #ICSA2025Rome with big announcements 🎉
✨ New ICSA President, VP & Steering Committee
✨ yICSA updates for the year ahead
✨ Poster Prize winners celebrated 🏆

Exciting news from the General Assembly at #ICSA2025Rome: the next ICSA meeting will take place in Seoul, South Korea in 2026!
Looking forward to seeing this community come together again.

Day 3 began with Session 7 at #ICSA2025Rome: exploring senescence pathways from mechanisms to therapeutic opportunities.
A strong finish to the scientific program!

Closing Day 2 of #ICSA2025Rome with the Gala Dinner & Party 🎉

Session 6 at #ICSA2025Rome linked senescence to aging pathologies — from telomere biology to organ function, frailty, and cancer.

A memory from Session 5 at #ICSA2025Rome: senescence and cancer at the crossroads of biology and therapy which also featured dynamic Flash Talks.

Remembering Session 4 at #ICSA2025Rome: a deep dive into the cellular mechanisms of senescence — spanning metabolism, mitochondria, and immunity.
A fascinating way to start Day 2!

It was great to be at #ICSA2025Rome grateful to present my research & connect with brilliant scientists. Thanks to MarcoDeMaria, @martakova.bsky.social & Fabrizio D’Adda di Fagagna for the outstanding organization! @icsasenescence.bsky.social @yicsac.bsky.social

Incredible conference the #icsarome2025!! Amamzing since and even better people, so lucky to have joined this community @icsasenescence.bsky.social.

@icsasenescence.bsky.social #icsarome2025. What a great meeting!! Thank you again for the organization, all the presentations and discussions!

Highlights from yICSA at #ICSA2025Rome 🌍✨
✔️Networking Social Event 🤝
✔️Special Session with career insights from @dimiccolab.bsky.social & @narita-lab.bsky.social 🙌
Thank you to everyone who joined us!
#yICSA #Senescence #ECR

I had a great time presenting my work on mtDNA replication and senescence from the @wanrooij20.bsky.social lab @umeauniversitet.bsky.social today at the #ICSA2025Rome conference, with super exciting discussions. Thanks a lot @icsasenescence.bsky.social and @yicsac.bsky.social !

We are greatly enjoying the exciting science (and location) at ICSA 2025 Rome #ICSA2025Rome @icsasenescence.bsky.social

Final day @icsasenescence.bsky.social 2005 meeting #icsa2025 Great science exciting sessions outstanding scientists. Thanks to the organizers @marcodemaria.bsky.social @martakova.bsky.social @FdAdF66 and to #UPO #agingproject for the Viral Infections&senescence session @irvinlab.bsky.social

A highlight of Day 1 at #ICSA2025Rome 🌟
Keynote by Laura Niedernhofer

#ICSA2025Rome Session 3 explored senescence across diseases 🧩
Talks on integrin signaling, mitochondria, muscle regeneration, infection, therapy resistance & reprogramming,

Viruses & senescence take the spotlight in Session 2 at #ICSA2025Rome

#ICSA2025Rome Session 1 – Unraveling the SASP I
Fantastic science to start the day!

Day 1 of #ICSA2025Rome kicks off! 🌍
Opening remarks by @marcdema.bsky.social
& Dot Bennett highlighting ICSA’s history and community.
Excited for a full day on senescence!

Excited to dive into fascinating science on cellular senescence! @yicsac.bsky.social @icsasenescence.bsky.social
#CellularSenescence #Aging #ICSA2025 #yICSA”

It was great having the chance to present some of the great work done by @victornzq.bsky.social in our lab at @cimususc.bsky.social within the fantastic #ICSA2025rome meeting. Thanks to @icsasenescence.bsky.social and the organizers, especially @martakova.bsky.social

So happy to be at the CNR in Rome hosting the 10th Annual @icsasenescence.bsky.social Meeting and the 2nd #PhaedonInstitute SenoTherapeutics Summit. It's finally time to sit back and enjoy the science 😎🥂
#ICSA2025Rome

I've just submitted my first UKRI fellowship application 🤞🎉meanwhile I've been out and about recently sharing early results of our research @nutritionsociety.bsky.social's SIG in Phytochemicals in Health @bsrageing.bsky.social and prepping for @icsasenescence.bsky.social Looking forward to it! 🔬🧪 🧬👩‍🔬

Registration is open!
Join the II International SENESCEL Conference on Cellular Senescence in Health & Disease 🧬
📍 Nov 6–7, 2025 | PRBB, Barcelona
🌍 senescel2025.senescel.org
Short talks & poster teasers for #ECRs!
@senescel.org @vrodillab.bsky.social

The countdown is on — the @icsasenescence.bsky.social Meeting in Rome is almost here! 🎉
We’re looking forward to seeing you, with plenty of activities and updates to come. Stay tuned!

@MartaMontes @ElenaGrossi8 @MaiteHuarteLab @CIMA_unav

#ICSAPaperOfTheMonth. sin-lncRNA interacts with the TCA enzyme DLST to maintain metabolic balance during senescence. Depletion of sin-lncRNA causes DLST translocation to the nucleus triggering transcriptional changes that lead to metabolic reprogramming in senescence.

#ICSAPaperOfTheMonth In this Neuron paper, Graves et al find that p16 expression—particularly in microglia (the brain resident immune cells) and endothelial cells (the primary component of blood vessels)—is necessary for tau-based neurodegenerative disease in mice.
www.cell.com/neuron/fullt...

Therapy-induced senescence is a transient drug resistance mechanism in breast cancer - Molecular Cancer Background Therapy-induced senescence (TIS) is considered a permanent cell cycle arrest following DNA-damaging treatments; however, its irreversibility has recently been challenged. Here, we demonstra...

molecular-cancer.biomedcentral.com/articles/10....
@AndrewFuredi, @eszterbajtai, @tantos_agnes, @ameplex, @ProtBioinfRG

#ICSAPaperOfTheMonth Breast cancer cells resist chemotherapy by entering a transient senescent state and evading immune detection. Instead of dying, they persist and can later escape senescence to drive relapse. Disrupting this cycle could lead to new treatment strategies.