@vaquez.bsky.social
A drawing showing elements of the pathophysiology of polycythemia vera.
The somatic JAK2 gain-of-function mutation valine to phenylalanine at codon 617 (exon 14) is found in ~95% of patients with in polycythaemia vera. #hemeonc
https://www.nature.c...
« C’est la panique ! » : privés de médicaments pendant longtemps, les patients contraints au système D -
Excellent article de @nicolasberrod.bsky.social avec le témoignage de Pierre un adhérent de @vivreavecunenmp.bsky.social
#MPNsm @ansm-gouv.bsky.social
www.leparisien.fr/societe/sant...
Thoughts on this? >> Pint Pharma Announces ANVISA’s Approval of BESREMi®
(ropeginterferon alfa-2b) for the Treatment of Polycythemia
Vera: SÃO PAULO–(BUSINESS WIRE)–Pint Pharma and PharmaEssentia announced today that ANVISA (Brazilian… >> Comment below! #healthtech #AI #industry40 #IoT #mhealth
Researchers at Brigham and Women's Hospital, Boston, recently found that ANC in 120 people with the Duffy null blood group can range from 1210-5390 microliters: significantly lower than most institutional reference ranges
Historically, ANC reference ranges have had a lower limit of 2000 microliters, but these were based on studies in populations with European ancestry, in whom the Duffy null phenotype is rare.
2/3 of people in the USA who self-identify as African-American have the Duffy null phenotype. It is also more common in people of Middle East and North African ancestry.
Could adjusting a simple blood test reference range save patients unnecessary stress?
Recent research highlights Duffy null-associated neutrophil count (DANC) and the risk it imposes on certain ancestral backgrounds.
Enroll in the ASH course: bit.ly/duffynull
#HemeSky #Hematology #MedSky
1/3 Merci à Yannick Sanchez pour ce reportage sur la pénurie de Pégasys diffusé hier dans le 20h de France 2.
www.francetvinfo.fr/sante/medica...
The latest NCCN Guidelines now highlight that ropeginterferon alfa-2b-njft (BESREMi®) can be used as a substitution for treating PV in the event that peginterferon alfa-2a (Pegasys®) is unavailable, helping maintain continuity of care.
us.pharmaessentia.com/wp-content/u...
‼️🩺 Les tensions d’approvisionnement en Pegasys s’accentuant, un protocole strict est mis en place à partir du 17.03 pour permettre l’accès au traitement, aux patients pour lesquels ce médicament ne peut être ni substitué, ni arrêté sans risque vital.
ansm.sante.fr/actualites/a...
Les tensions sur Pegasys s’accentuent : dès le 17 mars, dispense uniquement sur formulaire médical et ordonnance.
14.03.2025 15:56 — 👍 0 🔁 1 💬 0 📌 0
Cognitive fog in #polycythemiavera — what’s causing it?
PV patients sometimes report memory lapses, trouble focusing, but why? Research points to low oxygen delivery, microvascular issues & chronic inflammation.
We need answers. More research = better brain health.
Check out our March Monthly Publication on our website's homepage!
JAK2V617F impairs lymphoid differentiation in myeloproliferative neoplasms
www.mpnresearchconsortium.org
Le ciel est presque desoxyhemoglobinaire ce soir dans le 10ème !
13.03.2025 18:35 — 👍 1 🔁 0 💬 0 📌 0
🚀 J-7 avant la prochaine webconférence Allo Hémato : "NMP Regards croisés : vivre sa maladie en France et en Belgique", proposée en collaboration avec NMP Belgique !
📆 RDV mardi 18 mars à 19h. Inscriptions gratuite ci-dessous !
urls.fr/VpNwDd
#NMP
#npmsm
#belgique
Very proud of this first publication about healthcare transition for adolescents with Myeloproliferative Neoplasms #MPNsm
A huge thank you to pediatric hematologists and in particular Dr N. Kucine for the fantastic work and collaboration!
👇
onlinelibrary.wiley.com/doi/10.1002/...
