LaBella Lab

Ameya Jalihal of the @gladfelterlab.bsky.social asks how you maintain asynchrony in nuclear division?

Well... The cell isn't a free for all diffusion. Cellular condensates are critical to nuclear division asynchrony

Read more here: pmc.ncbi.nlm.nih.gov/articles/PMC...

Bacterial metabolites induce cell wall remodeling, antifungal resistance, and immune recognition of commensal fungi The fungus Candida albicans commensally colonizes mucosal surfaces in healthy individuals but can cause both superficial mucosal and life-threatening disseminated infections. The balance between comme...

Today is a good day to read our preprint about Candida albicans interactions with its neighbors! www.biorxiv.org/content/10.1... led by the amazing Faith Davis and a fantastic team of collaborators @kylaost.bsky.social @shannonrighi.bsky.social @balunaslab.bsky.social @tuowang.bsky.social

Audrey Williams of the @gladfelterlab.bsky.social uses GEMs 💎 to understand how the fungus A. pullulens can deal with incredibly high salt 🧂 concentrations

Deletion of core septin gene aspB in Aspergillus fumigatus results in fungicidal activity of caspofungin Septins are a family of GTP-binding proteins found in many eukaryotic lineages. Although highly conserved throughout many eukaryotes, their functions vary across species. In Aspergillus fumigatus, the...

Read more about this really cool story about the role of septins in enhancing the action of caspofungin antifungal activity

@mycorican.bsky.social

pmc.ncbi.nlm.nih.gov/articles/PMC...

@mycorican.bsky.social presents at the Tri-I symposium at Duke.

He begins by encouraging us to be more like Aspergillus... Resilient and adaptable

Woods Hole holds such a special place in my life and career.

WHOi summer program

Taking ALVIN home

Guest lecture at the MBL physiology course

@mblscience.bsky.social

Can't wait to come back!

Beach scene with “visit your village homosexual” written in the style of a tourism poster

Illuminati eye over the text “i believe in the one book theory”

Due to popular demand, we’ve introduced some new merch designs, including the highly requested village homosexual

ifbookspod.dashery.com

Navigating Bluesky: A Researcher's Quick Guide to Building Your Academic Network

Oh and welcome to Bluesky to those joining during #2025ISMPMI!

Tips:
Reposts matter more than likes here for increasing visibility (no algorithm).
Follow feeds for collected posts on specific topics (like Plant Science or Microbiology).

Other tips:
www.wiley.com/en-us/networ...

OrthoFinder just dropped a major update

It’s faster, more accurate, and ready for thousands of genomes

Let’s break it down (1/10)

github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...

Me, a white woman with fluffy curly hair and striped dress standing in front of a scientific poster with the figures from the linked preprint

Thanks to those who stopped by at #2025ISMPMI to learn about bacteria that live inside fungi.

It was great to hear your questions. So much to do in this area!!

For those not here, please check out our preprint: www.biorxiv.org/content/10.1...
Or mini-review: apsjournals.apsnet.org/doi/10.1094/...

I've wanted to write this article for years. About my and other's struggles to even survive sometime in #academia. Thank you to the amazing editors at @plosbiology.org that gave me the forum to write this piece. #science

The Meselson and Stahl experiment demonstrated in 1958 that DNA replicated semi-conservatively.

Meaning, each of the two strands of DNA serves as a template for a new copy to made of the complementary strand.

Foundational finding, elegant experimental design.

If I spend 2 hours thinking about a grant proposal but only end up with 2 lines...

Did I work for 2 hours or 2 minutes? ⏲️

In this light microscopy image of dividing cells within a Drosophila embryo, multiple centrosomes are labeled in cyan. Each centrosome is surrounded by a concentration of orange fluorescent dots, showing the localization of a model mRNA via single molecule detection.

Our lab @emoryuniversity.bsky.social Dept. of Cell Biology is hiring a research technician! This position is ideal for someone who enjoys research, organization, and working in a team. Come for a few years and publish with us, or stay to build a career. staff-emory.icims.com/jobs/149068/...

Amazing #Evol2025 !

New friends on Bluesky 🌌

Stunning science 🧬

Heartfelt rally calls 📣

Hope in the face of adversity 🫂

But... I will not miss the jingle jangle of those darn badges 🔕

Closing out Evolution #Evol2025 #Evol25 with a bang!

Liam Revell combines phylogenetic comparative biology & viral phylodynamics

New frontiers in phylogenetic comparative methods!

Menna Jones @mennajones.bsky.social describes a multi-regime bounded Brownian motion model

This model is assessed in frogs 🐸 to show that there may be shifts in developmental constraints

#Evol2025 #Evol25

Kyle David @kylethedavid.bsky.social discusses two new genome 🧬 duplications 🧬🧬 in the yeast subphylum

With three WGD clades, we can ask what are the causes and consequences of WGD in yeast

@evolutionvu.bsky.social @rokaslab.bsky.social

#Evol2025 #Evol24

Not accounting for codon evolution?

You may end up with large amounts of false positives in tests for selection!

academic.oup.com/mbe/article/...

#Evol2025 #Evol25

Hannah Verdonk @hverdonk.bsky.social describes Multiclass Synonymous Substitution (MSS) models

This model helps us avoid the trap of assuming all synonymous substitutions are created equal

The method captures selection on tRNA abundance

#Evol2025 #Evol25

Russell Dinnage @rdinnager.bsky.social proposes that Evolutionary Constraints present a challenge & opportunity to build better models

GenAI can learn the underlying constraints of evolution w/out proposing impossible states

Work in bird beaks 🐦🐤🦆🪿🐦‍⬛ demonstrates the possibilities!

#Evol2025

Alberto Rivera of the Baxevanis group @baxevanislab.bsky.social presents on the allorecognition in cnidarians 🪸

There is evidence for synteny and conservation across allorecognition complexes in Cnidaria... How does this compare to bilaterians?

#Evol2025 #Evol25

Read more about the limitations of BFMs due to evolutionary relatedness

arcadia-staging.pubpub.org/pdf/pub/idea...

#Evol2025 #Evol25

Ryan York of @arcadiascience.com discusses Biological Foundation Models

These models aim to soak up all biological data and spit out biological understanding

The models, however, are hitting a plateau

More parameters != More information

#Evol2025 #Evol25

Lei Curtis @leicurtis.bsky.social explores the role of inversions 🧬↔️🧬 in the Atlantic Cod 🐟

They combine results from multiple methods to identify the most likely inversions give within and between method variation

Small inversions happen! And they are common.

#Evol2025 #Evol25

If interested in #yeast phylogenomics, come to my talk on the Compendium of #Saccharomyces at #Evol2025 today at 2:30pm!

James Boyko @jboyko.bsky.social reminds us that comparative methods for trait evolution are highly dependent on model choice

He proposed new ideas for searching and optimizing model choice

#Evol2025 #Evol25

Olivia Brooks @olbrooks.bsky.social shares the evolution of autoresistance to toxins in amphibians 🐸

Sodium channels from 39 amphibians revealed some fascinating evidence for gene conversion

#Evol2025 #Evol25

Megan Phillips @meganphillips.bsky.social tells the tale of the little plasmid 🧬 that could 🦠

How does antimicrobial resistance impact the evolution of plasmids

#Evol2025 #Evol25