LaBella Lab

Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes As the tree of life becomes increasingly accessible to molecular investigations, describing mechanisms underlying evolutionary convergence and constraint will be crucial to understanding diversificati...

In a preprint with the @rokaslab.bsky.social , @linder-surprise.bsky.social developed a high-throughput extracellular acidification rate (ECAR) assay to evaluate glycolytic rate. We highlight how genetic traits, such as aerobic fermentation, can arise convergently with strong constraints. 🧬

a man sitting in front of a dell monitor ALT: a man sitting in front of a dell monitor

Some days I wish I had gotten a PhD in "Canvas Administration"

Nothing says professor like standing in a classroom full of students and not knowing how to unlock a module properly

GBE | From Trees to Traits: A Review of Advances in PhyloG2P Methods and Future Directions

In a new Review article in GBE, @scientific-arlie.bsky.social et al delve into the growing field of phylogenetic genotype to phenotype mapping (PhyloG2P), discussing advances and future directions for using phylogenomic data to map traits to genomes

🔗 doi.org/10.1093/gbe/evaf150

#genome #evolution

Dr. White @raw937.bsky.social discusses bats 🦇 and viruses at the Biomedical Symposium

Brad Bower of the NIH outlines the Strategic Plan for Data Science

Do you share your data in a usable way?

Where can AI take us next?

Excited for the Charlotte Biomedical Symposium today!

Intro to CIPHER by Dr. Jamie's featuring a @morgancarterphd.bsky.social Carter lab trainee

We are hiring! Oxford biology has three associate professorships available as we move to new state-of-the-art facilities

Three Associate Professor (or Professor) positions available at Oxford Biology. Come be my colleague! www.biology.ox.ac.uk/article/we-a...

✨ Are you a pre-tenure faculty or advanced postdoc with an academic offer in hand? 🎓 3 days left to apply for the SDB New Faculty Boot Camp! 🚀 Deadline: Aug 22, 2025 Apply here 👉 tinyurl.com/SDBFaculty

I'm hiring a postdoc to work in theoretical / computational phylogenomics! More info at tinyurl.com/63hb5ew8. Please share!

I have
NIGMS R35, impact score 12
NIHGRI R21, 4th percentile
NHGRI R01, 7th percentile (co-I)
and it seems like none will be funded. 0/3.

PO (who has been very helpful) said "Unfortunately, I do not expect this application will be selected for funding in FY25."

😭

𝐓𝐡𝐞 𝐅𝐮𝐭𝐮𝐫𝐞 𝐢𝐬 𝐅𝐮𝐧𝐠𝐢 𝐀𝐰𝐚𝐫𝐝 𝐢𝐬 𝐛𝐚𝐜𝐤—𝐫𝐞𝐚𝐝𝐲 𝐭𝐨 𝐛𝐚𝐜𝐤 𝐭𝐡𝐞 𝐧𝐞𝐱𝐭 𝐰𝐚𝐯𝐞 𝐨𝐟 𝐟𝐮𝐧𝐠𝐢 𝐢𝐧𝐧𝐨𝐯𝐚𝐭𝐨𝐫𝐬! 🌍🍄

The awards mission is to 𝐜𝐚𝐭𝐚𝐥𝐲𝐳𝐞 𝐠𝐫𝐨𝐮𝐧𝐝𝐛𝐫𝐞𝐚𝐤𝐢𝐧𝐠 𝐟𝐮𝐧𝐠𝐚𝐥 𝐢𝐧𝐧𝐨𝐯𝐚𝐭𝐢𝐨𝐧𝐬 that address some of humanity’s biggest environmental challenges—and to support the 𝐬𝐭𝐚𝐫𝐭𝐮𝐩𝐬 𝐚𝐧𝐝 𝐬𝐜𝐢𝐞𝐧𝐜𝐞 𝐞𝐧𝐭𝐫𝐞𝐩𝐫𝐞𝐧𝐞𝐮𝐫𝐬 pioneering these solutions

Ew... @theathletic.com

Do I "remember" the great Ilona Maher?!

I never forgot about her. She's been kicking ass this whole time!

Do better... not all your readers instantly forget about half of all athletes because of their gender

If interested in this or other ways that our lab uses Notion for recordkeeping and project management, I’ve now added a resource about it to our lab website.
#NewPI 🧪🦠
pages.charlotte.edu/carterlab/re...

Cannot stop laughing at this

Please help us spread the word! Please amplify!

We are searching for an associate or full professor (Canada Excellence Research Chair) in Biodiversity Genomics at the University of Guelph! 🐟🌿🦠🐜🐸🐝

Applications are due October 6 2025.

careers.uoguelph.ca/job/Guelph-C...

#AcademicJobs #EvoBio

Recruiting an NSF-funded Post-Doctoral Researcher in EEB The Budke Lab in the Department of Ecology & Evolutionary Biology at the University of Tennessee (http://jmbudke.github.io/) is seeking a Post-Doctoral Research Associate to work on an NSF-funded project. This project is investigating morphological evolution in a phylogenetic context using moss plants as the experimental system. The research responsibilities will include (1) assembling morphological datasets using the literature and herbarium specimens, (2) compiling DNA sequence datasets from publicly available resources and laboratory-based methods using herbarium specimens, and (3) combining these data to analyze the evolution of morphological structures across a phylogeny. Opportunities will also be available to develop novel research questions focusing on the functional morphology, physiology, and evolution of the parent-offspring relationship in mosses. Supervising and mentoring undergraduate researchers in both the laboratory and herbarium will be required. An additional aim of this project is to build awareness of and appreciation for plants and botanical natural history collections. As part of the team, the postdoc will participate in hands-on outreach events, such as Darwin Day. The postdoc will also co-lead a May-term course for undergraduate students on collections-based research. Apply by 17 August 2025 for full consideration.

Looking for a #postdoc in evolutionary biology?
Come join the Budke Lab! Read more about the lab jmbudke.github.io & apply at this link fa-ewlq-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...
This is the last weekend to apply before applications will be evaluated and zoom interviews scheduled.

Just to give the TL;DR on this one:

*The* main purpose of the EO is to move funding priorities and decisions away from experts and career professionals over to political appointees. With the ultimate power held by Vought / OMB.

New executive order puts all grants under political control All new funding on hold until Trump administration can cancel any previously funded grants.

New ArsTechnica story about the new steaming pile of Executive Order...

arstechnica.com/science/2025...

Phyling: phylogenetic inference from annotated genomes Phyling is a fast, scalable, and user-friendly tool supporting phylogenomic reconstruction of species phylogenies directly from protein-encoded genomic data. It identifies orthologous genes by searchi...

New #preprint from talented graduate student for a workflow we have been using for a while into a formal usage www.biorxiv.org/content/10.1...

Whole-genome sequencing of 490,640 UK Biobank participants - Nature A study reports whole-genome sequences for 490,640 participants from the UK Biobank and combines these data with phenotypic data to provide new insights into the relationship between human variation a...

✅ Published in @natureportfolio.nature.com today, the paper describing the initial whole-genome sequencing analysis of 500,000 UK Biobank participants.

Read here: www.nature.com/articles/s41...

I took several screenshots... It's impossible to capture anyone over zoom without it looking goofy <3

Amazing work from Dr. Anne Hatmaker @annemakerofhats.bsky.social at @canfunnet.bsky.social #CFN25

She takes us on a deep dive into the diversity of Penicillium isolates from diverse habitats

Today's the day!! If you are attending #CFN25 then check out my talk this afternoon at 4pm Eastern, 3pm Central! I'll be talking about Penicillium in the Fungal Genetics and Genomics III session 🍄 Looking forward to virtually seeing you soon!

Excited to tune into the CanFunNet meeting! @canfunnet.bsky.social

Check out our trainee Isha Jain's presentation on Friday in the Fungal Genetics & Genomics VI starting at 3:50pm

#CFN25

Great introduction to CanFunNet with Dr. Horianopoulos @linder-surprise.bsky.social

Ameya Jalihal of the @gladfelterlab.bsky.social asks how you maintain asynchrony in nuclear division?

Well... The cell isn't a free for all diffusion. Cellular condensates are critical to nuclear division asynchrony

Read more here: pmc.ncbi.nlm.nih.gov/articles/PMC...

Bacterial metabolites induce cell wall remodeling, antifungal resistance, and immune recognition of commensal fungi The fungus Candida albicans commensally colonizes mucosal surfaces in healthy individuals but can cause both superficial mucosal and life-threatening disseminated infections. The balance between comme...

Today is a good day to read our preprint about Candida albicans interactions with its neighbors! www.biorxiv.org/content/10.1... led by the amazing Faith Davis and a fantastic team of collaborators @kylaost.bsky.social @shannonrighi.bsky.social @balunaslab.bsky.social @tuowang.bsky.social

Audrey Williams of the @gladfelterlab.bsky.social uses GEMs 💎 to understand how the fungus A. pullulens can deal with incredibly high salt 🧂 concentrations

Deletion of core septin gene aspB in Aspergillus fumigatus results in fungicidal activity of caspofungin Septins are a family of GTP-binding proteins found in many eukaryotic lineages. Although highly conserved throughout many eukaryotes, their functions vary across species. In Aspergillus fumigatus, the...

Read more about this really cool story about the role of septins in enhancing the action of caspofungin antifungal activity

@mycorican.bsky.social

pmc.ncbi.nlm.nih.gov/articles/PMC...

@mycorican.bsky.social presents at the Tri-I symposium at Duke.

He begins by encouraging us to be more like Aspergillus... Resilient and adaptable

Woods Hole holds such a special place in my life and career.

WHOi summer program

Taking ALVIN home

Guest lecture at the MBL physiology course

@mblscience.bsky.social

Can't wait to come back!