Graeme Cowan 🧬👨🏻‍💻

Cochlin-Expressing Memory B (COMB) Cells Are Enriched in Autoimmune Diseases and Display a Distinct Activation Profile Rheumatoid arthritis (RA) is the most common chronic autoimmune arthritis, causing joint damage and affecting multiple organs over time. B cells play a key role in driving the disease by producing aut...

Why do B cells make (more) cochlin in RA, SLE and Sjogrens? A really interesting preprint, from @beccabelmonte.bsky.social and Mohini Gray at @edinuni-irr.bsky.social www.biorxiv.org/content/10.1...

Single-cell level characterization of B cell depletion and repopulation following rituximab in systemic lupus erythematosus Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used in the treatment of systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a dee...

Really enjoyed reading this preprint from Emma Davenport and Marina Botto’s labs. scRNAseq + AIRR of rituximab treatment in SLE - www.medrxiv.org/content/10.1...

*Please repost* @sjgreenwood.bsky.social and I just launched a new personalized feed (*please pin*) that we hope will become a "must use" for #academicsky. The feed shows posts about papers filtered by *your* follower network. It's become my default Bluesky experience bsky.app/profile/pape...

We're based in the Ashworth Laboratories, King's Buildings, University of Edinburgh. Photo shows the main staircase in the entrance to the Ashworth, stone steps from the 1920s, decorated with a series of bright, colurful banners depicting the science that's tackled in the building.

I'm very pleased to have two lab positions open this week, to join our team looking at immune regulation in infection and co-infection. We're especially interested in tissue-based immunity, cytokine regulation and immune metabolism. Join us! Postdoc (3y) and research technician (12mo) posts open.

Our search for a flow cytometry core facility manager for King's Buildings, University of Edinburgh, is finally live. Join us!

Conventional & spectral. Parasites, immune cells, algae, bacteria, yeast and more. Full-time, open-ended.

Apply by 17 March.

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Sorry, I just re-read the ENA email: “We would like to inform you that your studies have been made public with all associated data. Please be aware that it can take few days for this to be reflected in the ENA Browser.”. It looks like we need to wait for a few days before it’ll be searchable.

Raw data available at: www.ebi.ac.uk/ena, PRJEB83659

This should be an essential requirement for all studies and publications: data available ‘on reasonable request’ is not sufficient.

Frontiers | Deep sequencing of BCR heavy chain repertoires in myalgic encephalomyelitis/chronic fatigue syndrome

Our new publication on BCR sequencing in ME/CFS, adding to the evidence of an increased usage of IGHV3-30.

Much more immunological research is needed to understand the many lines of evidence indicating immune-mediated or autoimmune components to the disease.

www.frontiersin.org/journals/imm...

Donate to WHO’s Emergency Response Health Can’t Wait. Your Support Saves Lives Today.

Thanks Madhu, yes I was able to confirm that. Their donation website appears to be donate.who.foundation. I’m simply being cautious and trying to find out whether money donated through the donorsupport.co link actually gets to them. Do you know if it was WHO foundation that set up that link too?

I was unable to find any information that donorsupport.co was a legitimate website? The root URL has no website, and the domain registration is anonymous and only approx 4 years old. Is this a site that others are familiar with? Hopefully it is legit?

It’s wonderful to be at the University of Glasgow today to examine a viva. I think the last time I was here was 18 years ago for my own.

🙋🏻‍♂️ @jamieheather.bsky.social Could you please add me? Thanks!

125ml Erlenmeyer tissue culture flask holder by GC | Download free STL model | Printables.com Flask holder for shaking platform in TC incubator. Fits disposable PETG plain bottom flasks (e.g. Thermo 4115-0125) | Download free 3D printable STL models

If you happen to have this combination of TC needs and a Stuart mini orbital shaker, you can download and print one too: www.printables.com/model/108765...

Erlenmeyer tissue culture flasks on a shaking platform in a tissue culture incubator.

Having a day back in the lab expressing antibodies in Expi293 cells. Very excited to use my new 3d printed flask holder- much better than the old sticky mat!

Looking forward to this- just registered.

And @persmiseth.bsky.social

Also @pfvale.bsky.social

Welcome to BlueSky @uoe-eid.bsky.social !

Inspired by @rodrahimi.bsky.social 's noble efforts linking immunologists together over here, let's try and get more specifically TCR/BCR/AIRR/repertoire chat going with this starter park
go.bsky.app/Gi2dcGd
Drop me a beep to get added or suggest others!