David Tuller

David Tuller's Trial by Error Fall 2025 Help UC Berkeley raise $68,000 for the project: David Tuller's Trial by Error Fall 2025. Your gift will make a difference!

Berkeley's crowdfunder has reached 5% of the goal after its first day, with 49 donors! This pace won't keep up, but it's a decent start. Thanks to all past, current and future supporters!
crowdfund.berkeley.edu/project/47768

David Tuller's Trial by Error Fall 2025 Help UC Berkeley raise $68,000 for the project: David Tuller's Trial by Error Fall 2025. Your gift will make a difference!

Berkeley's fall crowdfunder for Trial By Error is now up!
crowdfund.berkeley.edu/project/47768

YouTube video by David M Tuller Interview with Yale immunologist Akiko Iwasaki

I spoke last week with Yale immunologist Akiko Iwasaki about her work on Long COVID. This interview has more than 1.3K views so far:
www.youtube.com/watch?v=nJTa...

Thanks to Yale's Akiko Iwasaki @virusesimmunity.bsky.social, a leading immunologist and Long COVID investigator, for talking with me yesterday about the recent Keystone Symposium, the
debate over viral persistence, and more. Here's our interview:
virology.ws/2025/09/26/t...

Long COVID is not FND, but some patients are getting diagnosed with it. Here’s what to do if it happens to you. - The Sick Times Some people with Long COVID are receiving potentially unhelpful diagnoses of functional neurological disorder (FND), a condition in which people experience neurological symptoms that cannot be attribu...

This piece for @thesicktimes.org about people with Long COVID receiving diagnoses of funcitonal neurological disorder...
thesicktimes.org/2025/09/26/l...

On Thursday there will be a preliminary injunction against the hospital. Pls help by reading & sharing this 🙏 #SaveSanne

@georgemonbiot.bsky.social @swastrosarah.bsky.social @nelehelena.bsky.social @davetuller1.bsky.social @anilvanderzee.bsky.social @tomkindlon.bsky.social @janetdafoe.bsky.social

Brian, they can't help themselves. It's such a deep-rooted instinct.

YouTube video by David M Tuller Interview with Ian Lipkin

Dr Ian Lipkin: "There's no question that threshold for triggering inflammation with ME/CFS is lower than the threshold in people who are healthy. So anything can set this off."

www.youtube.com/watch?v=-_ih...

Nowhere near discharge yet but having such a large meeting recognise the limited NHS resources available to clinicians & patients was a better starting point than yet a-n-other re-run of an argument lost in 2021, with PFD report and responses from 6 national bodies as evidence of the risks being run

#Savannah #vsME update. A good MDT which ran over to twice the length of time allocated. Dr Weir and I were both invited, spoke at length and were heard. The absence of NHS ME specialists _anywhere_ in the UK is the biggest probem for every ICB, including Lewisham and Greenwich.

that's brilliant!!

When an Australian ME/CFS study of an exercise intervention failed to find enough participants, the investigators decided to blame patient advicates instead of questioning their assumptions:
virology.ws/2025/09/08/t...

If Farage wins the next election, it will be down to one person. His name is Keir Starmer.
This thread explains why.
1. Destroying faith in democracy. The UK decisively voted out the Tories, only for Starmer to give us a Continuity Tory government, shamefully beholden to economic power.
🧵

Trial By Error: A (Satirical) Field Guide to Conducting Biopsychosocial Research in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) | Virology Blog By David Tuller, DrPH A reader from Belgium sent me the following (satirical) paper she'd written for the "Journal of Entrenched Paradigms." ...

A Belgian with ME/CFS sent me the following satirical "field guide to conducting biopsychsocial research in CFS/ME":
virology.ws/2025/09/02/t...

Here's a post highlighting recent blogs worth reading from
@julierehmeyer.bsky.social on Beth Mazur's death, @whitneydafoe.bsky.social on "real life," and @drelke.bsky.social on society's exercise obsession

virology.ws/2025/08/28/t...

They mention PEM in the discussion or limitations section, but it's irrelevant in the context of the trials in the meta-analysis, which are all over the place in defining their populations but did not generally seem to be identifying people with PEM.

A major journal, eClinicalMedicine, published a meta-analysis claiming "high-certainty" evidence for exercise for Long COVID--even though the paper also acknowledged that most of the data used was of poor quality. Hm. I sent a letter to the journal.
virology.ws/2025/08/27/t...

Thanks for helping me do it!!!

I really enjoyed our two-step show that day!!! It happened just as Trump was starting to dismantle the research enterprise in the U.S.

News bits: Update on Keystone gathering from
@thesicktimes.org; Severe ME Day video from
@anilvanderzee.bsky.social; Medscape article from @miriametucker.bsky.social on fractured care for postinfectious illness. virology.ws/2025/08/21/t...

well, thanks--I did what I could.

In a meta-analysis of Long COVID interventions, most RCTs included were at high risk of bias and the quality of evidence for outcomes measured was overwhelmingly of low or very-low quality. Yet authors claim "high-certainty" evidence for exercise interventions. Huh??
virology.ws/2025/08/16/t...

thanks. I'll check that out.

Apparently Paul Glasziou has blocked me because I pointed out he was promoting a meta-analysis in which the vast majority of clinical trials were at high risk of bias and 84% of the outcomes were of low or very low quality. Here's my take on the study hyped by Glasziou: virology.ws/2025/08/16/t...

Paul, you mean most of these randomized trials that are at high risk of bias (per Cochrane risk of bias tool) with outcomes whose quality is overwhelmingly of low or very low quality (per GRADE)? Got it! In Australia, I guess it's typical to take guidance from poorly designed research??

Unfortunately, Paul. 33 of the RCTs--more than half--were found to be at high ris of bias, per Cochrane's risk of bias tool, while only 3 had low risk of bias. And 84% of the outcomes yielded evidence that was of either very low or low quality. For that reason and others, the findings mean nothing.

YouTube video by David M Tuller Interview with Professor Chris Ponting about the DecodeME results.

I spoke with Profiessor Chris Ponting @cgatist.bsky.social about the DecodeME findings, which reported eight "genetic signals" in people with ME/CFS related to the nervous and immune systems: www.youtube.com/watch?v=CGUm...

Insane!!! At least as a matter of science. Maybe that's how they do things in medical sociology???

The BMJ has not published a rapid resopnse from Maeve Boothby O'Neill's mum, @swastrosarah.bsky.social‬, to its ME/CFS "hope" propaganda piece from members of the biopsychosocial ideological brigades. So I have posted it here. virology.ws/2025/07/23/t...

a man is holding a microphone in his mouth and saying if you smell ALT: a man is holding a microphone in his mouth and saying if you smell

Latest blog, breaking down some common narrative tricks bullshitters use so you can hopefully start to sniff it out a bit easier

Do you smell what the bull is shitting?
dontbelievehype.co.uk/bullshit-bre...