Dr. Peter Grinspoon

Dr. Peter Grinspoon

@grinspoon.bsky.social

Primary Care Doc. & #cannabis specialist Harvard Med. Substack: https://drpetergrinspoon.substack.com Books: Free Refills, Seeing Through the Smoke, Aging Well with Cannabis and CBD

1,049 Followers 1,203 Following 284 Posts Joined Nov 2024
17 hours ago
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Honored to speak on cannabis addiction at the United in Compassion medical #cannabis conference in Brisbane, Australia. It is a fantastic conference!

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20 hours ago
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Psilocybin or Nicotine Patch for Smoking Cessation This pilot randomized clinical trial compares prolonged smoking abstinence rates in smokers receiving psilocybin with those receiving the nicotine patch with both groups receiving manualized smoking c...

In this pilot randomized clinical trial, 1 dose of psilocybin with manualized CBT significantly increased long-term abstinence compared with nicotine patch treatment with CBT.
#psychedelics
jamanetwork.com/journals/jam...

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1 month ago
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When Drug Use Crosses the Line How to tell and how to help

Check out my latest blog. How do you know when your drug use is addictive or if it is reasonable? How does it affect your family? What are the guardrails? How do you distinguish "safe" drug use from #addiction?
drpetergrinspoon.substack.com/p/recreation...

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1 day ago
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Self-reported use of cannabidiol as a substitute or adjunct for approved medications - PubMed CBD use as a substitute or adjunct to medications was common among US adults particularly for pain medications. These patterns underscore the need for better evidence and clearer guidance on dosing, product quality, and co-use with other treatments.

CBD use as a substitute or adjunct to medications was common among US adults particularly for pain medications.
(fewer NSAIDs = fewer ulcers and less kidney damage...)
#cbd #cannabis
pubmed.ncbi.nlm.nih.gov/41725772/

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5 days ago
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Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: cohort study Objectives To investigate whether initiation of glucagon-like peptide-1 (GLP-1) receptor agonists is associated with both reduced risks of incident alcohol, cannabis, cocaine, nicotine, opioid, and ot...

Amazing study:
GLP-1 drugs [Wegovy, Ozempic...] 'associated with reduced risks of developing various incident SUDs [addictions], suggesting a broad preventive effect across multiple substance types.'
www.bmj.com/content/392/...

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6 days ago
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High Schools Are Losing the Struggle to Block Pot—Even During Class Legalization makes marijuana culturally acceptable and easy to get; ‘it was a party in the bathroom.’

Agree that teens need to avoid #cannabis use ("Just Say Wait"), but sensationalist @WSJ article ignores fact that teen usage of #marijuana is NOT rising with legalization (and weed has, unfortunately, always been easy to get for teenagers...)

www.wsj.com/us-news/educ...

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1 week ago
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Cannabis, Aging and Cognition: An Urgent Need for Research - Deepak Cyril D’Souza, Prakash Gupta, Ashley M. Schnakenberg Martin, Michael C. Stevens, Godfrey D. Pearlson, 2026

This article on need to study effects of #cannabis on older adults (I agree..) neglects that patients are using medical #marijuana INSTEAD of more dangerous pharmaceuticals like NSAIDS, opioids, benzos and hypnotics (e.g., Ambien) which is harm reduction.
journals.sagepub.com/doi/full/10.....

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1 week ago
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Massachusetts Ballot Measure To Roll Back Marijuana Legalization Is Opposed By Most State Residents, Poll Shows - Marijuana Moment Massachusetts voters will have a chance to vote on a ballot initiative in November that would roll back the state’s adult-use marijuana law—and a new poll shows that an overwhelming majority of reside...

Poll of Massachusetts residents found that they overwhelmingly oppose a proposed ballot initiative to roll back the state's marijuana legalization law, 63 percent to 20 percent.
Editorial: great idea to start locking up Black people for #cannabis use again
www.marijuanamoment.net/massachusett...

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1 month ago
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Is Cannabis Addictive? How addictive?

Big topic: is #cannabis addictive? How addictive? What are we doing wrong in the field of #addiction medicine. Check out my blog.
drpetergrinspoon.substack.com/p/is-cannabi...

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3 weeks ago
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Lifetime Cannabis Use Is Associated with Brain Volume and Cognitive Function in Middle-Aged and Older Adults - PubMed Results highlight that cannabis may influence brain health differently across the lifespan, potentially offering protective effects in older age while posing risks earlier in development. Protective effects may result from endocannabinoid-mediated modulation of inflammation, immune function, and neu …

'Results highlight that #cannabis may influence brain health differently across the lifespan, potentially offering protective effects in older age while posing risks earlier in development.'
pubmed.ncbi.nlm.nih.gov/41379083/

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1 month ago
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When Drug Use Crosses the Line How to tell and how to help

Check out my latest blog. How do you know when your drug use is addictive or if it is reasonable? How does it affect your family? What are the guardrails? How do you distinguish "safe" drug use from #addiction?
drpetergrinspoon.substack.com/p/recreation...

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1 month ago
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Trump Allies Near ‘Total Victory’ in Wiping Out U.S. Climate Regulation

Among horrible things Trump doing (trying to destroy elections & our democracy, torturing immigrants, ICE shoot innocent protestors, destroying alliances, ballooning our debt), this is diaster: to make his oil/coal friends rich, he's destroying our climate
www.nytimes.com/2026/02/09/c...

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1 month ago
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Healthcare utilization and developmental delay among infants exposed to cannabis in utero We examined the association between in utero cannabis exposure and well child care (WCC) attendance, emergency department (ED) visits, and developmental delay (DD) diagnosis during the first two years...

I counsel against using #cannabis during pregnancy (unless under a few, extreme conditions...), but the data on harms is very mixed. This study shows no measurable harms with respect to ED visits, or developmental delay.
www.academicpedsjnl.net/article/S187...

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1 month ago
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Is Cannabis Addictive? How addictive?

Big topic: is #cannabis addictive? How addictive? What are we doing wrong in the field of #addiction medicine. Check out my blog.
drpetergrinspoon.substack.com/p/is-cannabi...

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1 month ago
YouTube
Cannabis EXPERT Shares Surprising Benefits for Seniors YouTube video by Peter Grinspoon

Check out one of my most popular video on the myriad uses of #cannabis in seniors
(I have book coming out on this topic on 5/5/26)
www.youtube.com/watch?v=jGJy...

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1 month ago
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Big Cannabis just funneled millions to Trump Undermining the social justice movement that legalized cannabis

New blog:
In what universe does it make sense for Big Cannabis to bankroll Trump? When corporate cannabis aligns with anti-democratic power, it betrays the patients and activists who fought for legalization. We need legalization without corruption.

drpetergrinspoon.substack.com/p/big-cannab...

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1 month ago
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The Exploration of Cannabis Beverage Substitution for Alcohol: A Novel Harm Reduction Strategy Alcohol consumption is associated with nearly 200 health conditions. As cannabis-infused beverages emerge in the legal market, their potential as a substitute for alcohol is of growing interest. Th...

'Findings suggest cannabis beverages may support alcohol substitution and reduce alcohol-related harms, offering a promising alternative for individuals seeking to lower alcohol intake.'
#cannabis #harmreduction
www.tandfonline.com/doi/full/10....

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1 month ago
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Opinion | Trump Could Interfere With the Midterm Elections. You Can Help Defend Them.

Important article about upcoming elections:
www.nytimes.com/2026/01/31/o...

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1 month ago
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The Exploration of Cannabis Beverage Substitution for Alcohol: A Novel Harm Reduction Strategy Alcohol consumption is associated with nearly 200 health conditions. As cannabis-infused beverages emerge in the legal market, their potential as a substitute for alcohol is of growing interest. Th...

Another study suggesting that people are substituting #cannabis for #alcohol, which is a critical way to accomplish harm reduction.

www.tandfonline.com/doi/abs/10.1...

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1 month ago
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Chicago’s United Center to offer cannabis drinks – could other arenas follow? Drinks to be sold at concerts under federal legislation but attenders may have to wait to imbibe at sporting events

Honored to be included in this interesting Guardian article -- the world is changing! (for the better); though: use #cannabis with caution (and not with alcohol...)

www.theguardian.com/us-news/2026...

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1 month ago
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Big Cannabis just funneled millions to Trump Undermining the social justice movement that legalized cannabis

New blog:
In what universe does it make sense for Big Cannabis to bankroll Trump? When corporate cannabis aligns with anti-democratic power, it betrays the patients and activists who fought for legalization. We need legalization without corruption.

drpetergrinspoon.substack.com/p/big-cannab...

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1 month ago
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Man shot and killed by federal officers in Minnesota was an ICU nurse, his parents say The man who was shot and killed by a federal officer during an immigration operation has been identified as 37-year-old Alex Pretti, an intensive care unit nurse.

Off topic for me -- but we all need to push back against ICE, Trump's version of the Gestapo, which is harming (and now murdering) innocent civilians/peaceful protesters; most of the immigrants peaceful too - Trump is destroying fabic of our democracy.
www.pbs.org/newshour/nat...

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1 month ago
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High January Is the New Dry January

As long as people are careful not to consume too much THC, and don't plan on driving, #cannabis drinks are significantly safer than alcohol (which was associated with 178,000 deaths last year); this is harm reduction.

www.nytimes.com/2026/01/25/b...

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1 month ago
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The nature of today’s unregulated drug supply has changed dramatically. In this video, I explain the risks of pressed pills and fentanyl contamination, and discuss what this means for harm reduction and drug policy.

Watch the full video here: lnkd.in/eXQ6cNbR

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1 month ago
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Excited to speak on Feb. 9th. at 12:30, with wonderful panel, at The Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics at Harvard Law School on #cannabis policy! (and I'm at MIT addiction bootcamp today).

petrieflom.law.harvard.edu/events/detai...

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1 month ago
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US drug policy does not align with experts’ rankings of drug harms: a multi-criteria decision analysis - Harm Reduction Journal Background United States drug policy is primarily based on the Controlled Substances Act of 1970 and largely contradicts scientific evidence about how to mitigate drugs’ harms. Expert consensus on dru...

Shocking!
'US drug policy does not align with experts’ rankings of drug harms: a multi-criteria decision analysis'

#cannabis was in the middle and mushrooms were the least dangerous...has no relationship to how these substances are scheduled in CSA.
link.springer.com/article/10.1...

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1 month ago
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Vaporized cannabis versus placebo for acute migraine: A randomized, double-blind, placebo-controlled crossover trial - PubMed Acute migraine treatment with 6% THC + 11% CBD was superior to placebo at 2-h post-treatment with sustained benefits at 24 and 48 h.

'Acute migraine treatment with 6% THC + 11% CBD was superior to placebo at 2-h post-treatment with sustained benefits at 24 and 48 h.'
(ramdomized, double-blind, placebo controlled)
#cannabis #migraine
pubmed.ncbi.nlm.nih.gov/41469488/

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1 month ago
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The nature of today’s unregulated drug supply has changed dramatically. In this video, I explain the risks of pressed pills and fentanyl contamination, and discuss what this means for harm reduction and drug policy.

Watch the full video here: lnkd.in/eXQ6cNbR

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2 months ago
YouTube
A Brother's Battle with Leukemia and What Cannabis Did YouTube video by Peter Grinspoon

Before I was a doctor, I was a kid watching my older brother Danny endure chemo for leukemia. Cannabis was the only thing that stopped the nausea & vomiting before he died at 16. It was the '70s, and using it meant breaking the law. Watch the full video at youtu.be/-MWHVhlIHwk

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1 month ago
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Older Adults’ Perspectives on and Experiences with Cannabis Use: Results From the 2024 National Poll on Healthy Aging Cannabis use is increasing among older adults, concurrent with regulations allowing medical and/or recreational consumption, increases in the THC potency of cannabis products, and declining public perceptions of cannabis-related risks. Using a ...

Interesting results:
'Older Adults’ Perspectives on and Experiences with Cannabis Use: Results From the 2024 National Poll on Healthy Aging'
(this is what my upcoming book is about, #cannabis use in seniors, how to use it safely...)
pmc.ncbi.nlm.nih.gov/articles/PMC...

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