Gautam Dey

RNA-specific local translation is patterned by condensates for multinucleate cell growth - Nature Cell Biology Geisterfer, Jalihal et al. show spatially distinct effects of Whi3 condensates on target translation in Ashbya syncytia. In vitro, translation is enriched at condensate–solute interfaces but repressed...

Condensates are powerful ways to break symmetry and cells do remarkable things with them. Here we show that in a multinucleate fungus, a condensate regulates translation of a cyclin and a formin in distinct locations.
www.nature.com/articles/s41...

Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you!
1/n

An unconventional Rubisco small subunit underpins the CO2-concentrating organelle in land plants In many algae, photosynthesis is boosted by biophysical CO2-concentrating mechanisms, which pack the CO2-fixing enzyme Rubisco into liquid-like organelles called pyrenoids. Engineering C3 crops with a...

Our work on #hornwort #pyrenoids is finally out in @science.org! 🎉 We uncovered how hornworts pack their Rubisco into pyrenoids and successfully recreated them in Arabidopsis. A key step toward engineering more efficient photosynthesis in crops @btiscience.bsky.social www.science.org/doi/10.1126/...

I thought about this very deeply for many days Holly. Action shot on the right for the win 🥇

Thirty-six solutions to stabilize Earth’s climate An updated visual assessment tool can bridge the gap between climate research and political action

Thirty-six solutions to stabilize Earth’s climate | Science www.science.org/doi/10.1126/... 🧪

🚨 New paper from our lab just published in Nature🚨

www.nature.com/articles/s41...

Discover how 🌱 tumour formation is shaped by tissue context from the very beginning. Cancer is not driven by genetics alone

✨Fantastic team led by Greta Skrupskelyte, Eduardo Rojo, @hariajith.bsky.social

Cover image of paperback edition of the Tree of Life book by Max Telford.

On world book day might you be tempted to preorder the paperback edition of The Tree of Life?

Out in pb on April 23rd.

www.amazon.co.uk/Tree-Life-So...

Help! We're struggling to choose between these two images of #Mesodinium #karmachamaeleon and its cryptophyte prey, one more "documentary" and one more "action shot," as cover image submissions (to a society journal). If you were an editor, which one would more likely catch your eye? #protistsonsky

After several years of work, my lab is starting to put out our first papers on learning in a unicellular organism (Stentor coeruleus).

Here we show evidence for a form of associative learning in Stentor:
www.biorxiv.org/content/10.6...

We are one of the potential host labs for a Lecturer position in Molecular Genetics & Genomics — please share, and get in touch for more info! 🧬📣

I had fun writing this N&Vs on two fascinating new papers on centromere evolution in yeast. If you’re interested in how centromeres adapt yet stay functional, here’s my take. rdcu.be/e6DD0 @nature.com @gautamdey.bsky.social @gsherloc.bsky.social @helsenjana.bsky.social @maxhaase.bsky.social

Fungal Cryptography — The Evolution of Molecular Specificity at University College London on FindAPhD.com PhD Project - Fungal Cryptography — The Evolution of Molecular Specificity at University College London, listed on FindAPhD.com

⏰ Last chance to apply for this PhD position with my colleague Kabir Husain (not on bsky: kabirhusain.github.io) at @lmcb-ucl.bsky.social

Fungal cryptography & the evolution of molecular specificity

📆 Deadline: 4th March 2026

www.findaphd.com/phds/project...

You are finishing your PhD and looking to continue in science?

The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....

Thanks for reposting!

Our Lab is searching a postdoc for an exciting ERC-funded project that will start this summer. Apply if you’re passionate about multi-omics, cutting-edge computational approaches, and exploring biological questions across the animal 🪼 🪱 🐞 🦎 🦋 🕷️ tree of life www.biozentrum.unibas.ch/open-positio...

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧵 (carried over from the old place)

Be part of OMGN! Open to all researchers with an interest in oomycetes, from molecular genetics & genomics to biology, population biology, and ecology, at either an experimental or a computational level. Investigators new to the field are always welcome oomycetes.com

We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social

Please get in touch if you have any questions.
www.nature.com/naturecareer...

Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate - Nature The choanoflagellate Choanoeca flexa forms motile and contractile cell monolayers purely clonally, purely aggregatively or through a combination of both processes depending on environmental condi...

Salinity tunes mode of multicellularity in a tidepool choanoflagellate www.nature.com/articles/s41... - paper in @nature.com

In addition to all the well-documented stresses on the system, reviewer fatigue/saturation drives worse reviews which in turn promotes more journal shopping by authors which leads to paper recirculation and, yes, you guessed it, more reviewer fatigue 😵‍💫

@reviewcommons.org @asapbio.bsky.social

The best stories are the personal ones. So before we get to the new preprint, stay awhile and listen

#MobileLabs #TREC

Have you ever wondered 🤔... Does phenotypic variance respond to environmental perturbation? Does it have a genetic basis? Are mean and variance regulating loci exposed to different selection pressures? These and more questions are explored in our new preprint 🔥

www.biorxiv.org/content/10.6...

Interested in the most recent developments in plant science? Join the Mendel Early Career Symposium on May 21-22 at the @viennabiocenter.bsky.social to exchange with experts about their science and career trajectories. Register by March 13th for a talk. More here: www.oeaw.ac.at/gmi/news-eve...

🤩to see this behemoth of a story out !
Pushed by @nikobiota.bsky.social & the Amazing @embl.org AML Team (Tina, Michael, Paulina) and in Co. with the Best #science #family you can dream of!

This truck was #home, for weeks in a row & in my heart for a lifetime.

www.biorxiv.org/content/10.6...

For what?

Excited to share our new preprint exploring how Paramecium achieves diverse flow functions, i.e. feeding and swimming, simultaneously. This work was spearheaded by our ExM expert, PhD student Daphne Laan @daphnelaan.bsky.social :
www.biorxiv.org/content/10.6...

Fig. 2 Life cycle of Cyanidiophyceae.

✨ Paper spotlight ✨

(🧵 1/2) Fascinating single cell red algae: models for evolution and adaptation
nph.onlinelibrary.wiley.com/doi/10.1111/...

#PlantScience

@embl.org at its best: collaborative, open, transformative, and just the right amount of crazy. Dreaming of mechanistic cell biology *in the natural environment*? Dream no more, rent the AML.

www.biorxiv.org/content/10.6...

www.youtube.com/watch?v=jepb...

#WeFreezeOnTheBeach #ProtistsOnSky 🦠🌍🧪

Global genetic rewiring during compensatory evolution in the yeast polarity network - EMBO Reports Functional defects resulting from deleterious mutations can often be restored during evolution by compensatory mutations. Importantly, this process can generate the genetic diversity seen in networks ...

And another paper!
We show that compensatory evolution in the yeast polarity network leads to global genetic rewiring: restoring polarity reshapes gene disruption tolerance across the genome and rewires entire cellular processes—not just individual genes.
doi.org/10.1038/s44319-026-00709-4

📢 Institut Jacques Monod Seminar

📅 February 27th
📍 Institut Jacques Monod

Invited by the @ishier.bsky.social, @gautamdey.bsky.social will present the Institut Jacques Monod seminar "Evolution and diversity of mitosis"

➡️ buff.ly/uCSfjgQ

EMBO Press co-evolves with molecular ecology and evolutionary biology - The EMBO Journal The EMBO Journal - Molecular ecology and evolution are central to understanding how biological systems function, interact, and diversify. A special issue of this journal reflects the growing...

Read how @embopress.org is expanding its focus on molecular ecology and evolution as central underpinnings of functions/interactions/diversification of biological systems – by @yehumoran.bsky.social, @berndpulverer.bsky.social, and our new team of Editorial Advisors
link.springer.com/article/10.1...