Iannacone Lab

From Histology to High‐Resolution Mapping: The Rise of Spatial Omics in Immunology Immune regulation is fundamentally spatial, shaped by tissue architecture and local cues. Spatial omics—transcriptomic, proteomic, metabolomic, lipidomic, and phosphoproteomic platforms—preserve coor...

Our review "From Histology to High-Resolution Mapping: The Rise of Spatial Omics in Immunology" is now online! onlinelibrary.wiley.com/doi/10.1002/...

📣 EJI is proud to share that this year’s Nobel Prize winner, Shimon Sakaguchi, published with us on 6 October: bit.ly/46R7n4g
We extend our heartfelt congratulations to Shimon for receiving the prize in recognition of his pioneering work on Tregs. #NobelPrize #Immunology #Tregs

Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be....

(2/2) Fun collaboration with @linterman.bsky.social lab. Huge congrats to @cristianbeccaria.bsky.social & @smguillaume.bsky.social for spearheading this! onlinelibrary.wiley.com/doi/10.1111/...

Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be....

🧵 (1/2) Interested in tertiary lymphoid structures (TLSs)? Check out our latest review, where we chart how TLSs form across organs and contexts — from lung to liver, CNS, skin, gut & more — and their dual roles in protection vs. pathology.

Great to have this out, and such a pleasure to work together. @smguillaume.bsky.social @cristianbeccaria.bsky.social @iannaconelab.bsky.social

Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be...

So happy to share that our review in #ImmunolRev is finally out! 😃 We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration!
dx.doi.org/10.1111/imr.70063

Don't forget to secure your place at our new conference!
Cancer Immunology: Across Space & Time
📅Date: 10 Jul - 13 Jul 2026
🌏Location: Lisbon, Portugal
📢Early Bird & Talk Submission: 15th January 2026
Don't miss out, Register now: bit.ly/3IdEwii
#CancerImmuno #FusionImmunology #FusionCancerResearch

Excited to present at the next OBS immuno seminar our recent work from the @iannaconelab.bsky.social! Happy to make science open for everyone 🌈💜

IUIS 2025: Day 3 Podcast Episode · The Immunology Podcast · 08/21/2025 · 25m

@iannaconelab.bsky.social presenting our work at #IUIS @iuis-online.bsky.social in Vienna highlighting the importance of CD4 T cell mediated help in the liver! 🚀 Thanks @immunologypodcast.com for highlighting our story! @cristianbeccaria.bsky.social podcasts.apple.com/us/podcast/t...

🌟Cheers to the #ACTERIA Early Career Awardees! #EFIS is proud to have supported young scientists and hope Vienna inspired you with new connections, and ideas. 🤝Here’s to the next 50 years of advancing science together!💙
@yefis-immunology.bsky.social @eurjimmunol.bsky.social @iannaconelab.bsky.social

Thrilled to share some of the stories we've been working on in our @iannaconelab.bsky.social at #IUIS2025 @iuis-online.bsky.social in Vienna! Excited to chat with so many friends and colleagues from around the world! @davidemarotta.bsky.social @CaitlinAAbbott

Steffen Jung announced Andreas Radbruch as keynote speaker at #IUIS2025, highlighting his strong support for European Immunology and the importance of backing EJI and European research!

Andreas presenting his newest EJI article by Schneider-Revueltas et al. onlinelibrary.wiley.com/doi/10.1002/...

EJI & EFIS are proud to announce the brand-new ECR Article of the Year Award 🏆

Presented by EJI’s Editor-in-Chief Matteo Iannacone at #IUIS2025, this prize celebrates outstanding research by early career researchers published in EJI 🎉

Check the eligibility criteria here👇
bit.ly/3Hvn9t5

Thanks for sharing @brendaraud.bsky.social and @immunologypodcast.com!

📢 Call for papers! Our special issue on Autoimmunity & Environmental Factors is open for submission.

✅Guaranteed peer review for all #IUIS2025 participants!

Contribute to advancing our understanding of how modifiable factors influence immune tolerance and autoimmunity 👉 bit.ly/3HFEgIA

Editor-in-Chief Nadja Bakocevic presenting at #IUIS2025 Career Fair on the ways @eurjimmunol.bsky.social and @efis-immunology.bsky.social support early career researchers.

✨ Celebrating 50 years of EJI and introducing the brand-new ECR Article of the Year Prize!

🔬 #EFIS will be at the #IUIS2025 exhibition hall!

Come say hello, discover our programs, network with fellow immunologists, learn about EJI prizes, and grab some treats✨

📅 Aug 17–21 | 📍 Booth # 42

#Immunology

@eurjimmunol.bsky.social @yefis-immunology.bsky.social

📢 EJI is at #IUIS2025 in Vienna!
Come meet us at the EFIS booth #42 😃

We’d love to hear about your science, answer your publishing questions, and connect with the global immunology community 🔬🌍

See you there! 👋

@yefis-immunology.bsky.social @efis-immunology.bsky.social @iuis-online.bsky.social

Do not miss it! 👇

What can I say... my watercolor made it to the cover of the latest issue of @natimmunol.nature.com, together with our paper on IL-27 in chronic hep B 🚀 We really put the cherry on top in the @iannaconelab.bsky.social @cristianbeccaria.bsky.social. 🥹💜 Check it out! www.nature.com/ni/volumes/2...

Venzin and Beccaria et al. demonstrate that pre-activated CD4+ T cells actively license local hepatic APCs and restore antiviral CD8+ T cell function. bit.ly/4kRAbhS  ‪@valentinavenzin.bsky.social‬  @cristianbeccaria.bsky.social‬  ‪@iannaconelab.bsky.social‬

Members of the Iannacone Lab

Drs. @valentinavenzin.bsky.social, @cristianbeccaria.bsky.social, and the @iannaconelab.bsky.social identified the molecular and cellular mechanisms by which CD4⁺ #Tcells can restore antiviral CD8⁺ T cell function in the #liver.

@natimmunol.nature.com: go.nature.com/3Ggjajr
🎧: bit.ly/3GP9NaK

Ep. 109: "Phagocyte Cell Biology" Featuring Dr. Johnathan Canton - The Immunology Podcast Dr. Johnathan Canton is an Assistant Professor at the University of Calgary, where his lab uses advanced microscopy techniques to study dendritic cells, macrophages, and innate immunity. He talks abou...

Thank you @brendaraud.bsky.social and @drsifujg.bsky.social for highlighting our recent @natimmunol.nature.com (25:40) www.immunologypodcast.com/ep-109-phago...

A liver-centric help circuit revives CD8+ T cells via IL-27 - Nature Immunology Effector CD4⁺ T cells restore antiviral CD8⁺ T cell function in the liver by licensing Kupffer cells via CD40–CD40L interactions. This triggers IL-27 production and reprograms the hepatic immune envir...

If you’re too busy to read the paper, here’s the Research Briefing in Nature Immunology 🌈 a quick dive into how CD4⁺ T cells and IL-27 revive CD8⁺ T cells right in the liver! @natimmunol.nature.com @iannaconelab.bsky.social www.nature.com/articles/s41...

Targeting HBV with RNA interference: Paths to cure RNA-targeting therapies hold promise for contributing to HBV cure regimens, but challenges remain before that promise can be realized.

Happy to share our latest review "Targeting HBV with RNA interference: Paths to cure"| Science Translational Medicine www.science.org/doi/10.1126/... written together with @cristianbeccaria.bsky.social, Lena Allweiss, Julie Lucifora, John Tavis, Adam Gehring and Maura Dandri

Grazie!

Thanks for sharing!

Thank you Laura!

Thanks Ivan 😊

@immunologypodcast.com @microbetv.bsky.social @erc.europa.eu @embopress.org @embo.org @unisr.bsky.social