CD4+ T cells license Kupffer cells to reverse CD8+ T cell dysfunction induced by hepatocellular priming - Nature Immunology
Here the authors show that CD4+ effector T cells prevent or reverse CD8+ T cell dysfunction by licensing Kupffer cells to trigger IL-27 production, defining a liver-specific immune circuit and a poten...
Honoured to see our @natimmunol.nature.com study highlighted in a thoughtful @jhepatology.bsky.social commentary on the IL-27/Kupffer cell axis in chronic HBV β a great summary of why tissue immunity matters and of our work.
Paper: tinyurl.com/yt652mxa
Commentary: tinyurl.com/56pke5x5
23.11.2025 15:21 β π 5 π 1 π¬ 0 π 0
New review out! π 20 years after itβs discovery, with @iannaconelab.bsky.social we decided to bring together what we currently know about this cytokine and how it shapes CD8 T cell responses. A small contribution to make sense of a field that is moving fast π @cp-trendsimmuno.bsky.social
20.11.2025 12:43 β π 9 π 3 π¬ 0 π 0
Reframing IL-27: a central regulator of CD8+ T cell immunity
Interleukin-27 (IL-27), a member of the IL-12 cytokine family, was long viewed primarily as a regulator of CD4+ T cell immunity. Subsequent studies reβ¦
New review out in @cp-trendsimmuno.bsky.social! With @valentinavenzin.bsky.social, we revisit IL-27 as a central regulator of CD8βΊ T cell fate β integrating insights from infection, cancer, and autoimmunity, and outlining its therapeutic potential. www.sciencedirect.com/science/arti...
20.11.2025 06:24 β π 6 π 3 π¬ 0 π 0
#CancerImmuno speaker list is live!π’
Join us in sunny Lisbon, July 2026. Register now and submit your talk to share your research.
Early Bird Deadline: 15 Jan 2026
π Click here to register: bit.ly/4qZVqmd
#FusionImmunology #FusionCancerResearch
17.11.2025 15:56 β π 6 π 5 π¬ 1 π 0
π€ Our next episode it out!
We chat with Professor Matteo Iannacone ( @iannaconelab.bsky.social ) from @@unisr.bsky.socialabout his work understanding the generation of dysfunctional adaptive immune cells in chronic #HepatitisBVirus infection.
π§ Listen now: https://bit.ly/4o2W8xa
21.10.2025 17:28 β π 3 π 3 π¬ 0 π 0
Join us for this exciting meeting! @embo.org Workshop "Pathogen Immunity and Signalling", 8-12 June, 2026, Leiden, The Netherlands meetings.embo.org/event/26-pat...
18.10.2025 06:55 β π 19 π 10 π¬ 2 π 1
πKicking off the 50th annual SSI meeting in Stockholm! Huge thanks to @cgerlachlab.bsky.social for the warm welcome and inspiring introduction!
@yssi-immunology.bsky.social @yefis-immunology.bsky.social @efis-immunology.bsky.social @swimm-immuno.bsky.social @iannaconelab.bsky.social
15.10.2025 07:41 β π 10 π 4 π¬ 0 π 0
π Congratulations to this year's SSI Young Investigator Award winners! Meet the rising stars of Scandinavian #immunology: John, Jonna, Chris, and AsbjΓΈrn @yssi-immunology.bsky.social @yefis-immunology.bsky.social @efis-immunology.bsky.social @iannaconelab.bsky.social @romagnanilab.bsky.social
16.10.2025 09:21 β π 17 π 10 π¬ 0 π 0
π£ EJI is proud to share that this yearβs Nobel Prize winner, Shimon Sakaguchi, published with us on 6 October: bit.ly/46R7n4g
We extend our heartfelt congratulations to Shimon for receiving the prize in recognition of his pioneering work on Tregs. #NobelPrize #Immunology #Tregs
07.10.2025 08:43 β π 19 π 8 π¬ 0 π 1
Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers
Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be....
𧡠(1/2) Interested in tertiary lymphoid structures (TLSs)? Check out our latest review, where we chart how TLSs form across organs and contexts β from lung to liver, CNS, skin, gut & more β and their dual roles in protection vs. pathology.
26.09.2025 07:19 β π 7 π 2 π¬ 1 π 0
Great to have this out, and such a pleasure to work together. @smguillaume.bsky.social @cristianbeccaria.bsky.social @iannaconelab.bsky.social
25.09.2025 19:53 β π 21 π 6 π¬ 0 π 0
Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers
Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be...
So happy to share that our review in #ImmunolRev is finally out! π We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration!
dx.doi.org/10.1111/imr.70063
25.09.2025 19:12 β π 17 π 5 π¬ 0 π 3
Don't forget to secure your place at our new conference!
Cancer Immunology: Across Space & Time
π
Date: 10 Jul - 13 Jul 2026
πLocation: Lisbon, Portugal
π’Early Bird & Talk Submission: 15th January 2026
Don't miss out, Register now: bit.ly/3IdEwii
#CancerImmuno #FusionImmunology #FusionCancerResearch
10.09.2025 10:27 β π 2 π 2 π¬ 2 π 0
Excited to present at the next OBS immuno seminar our recent work from the @iannaconelab.bsky.social! Happy to make science open for everyone ππ
04.09.2025 21:16 β π 4 π 1 π¬ 0 π 0
IUIS 2025: Day 3
Podcast Episode Β· The Immunology Podcast Β· 08/21/2025 Β· 25m
@iannaconelab.bsky.social presenting our work at #IUIS @iuis-online.bsky.social in Vienna highlighting the importance of CD4 T cell mediated help in the liver! π Thanks @immunologypodcast.com for highlighting our story! @cristianbeccaria.bsky.social podcasts.apple.com/us/podcast/t...
22.08.2025 12:13 β π 7 π 2 π¬ 0 π 0
Steffen Jung announced Andreas Radbruch as keynote speaker at #IUIS2025, highlighting his strong support for European Immunology and the importance of backing EJI and European research!
Andreas presenting his newest EJI article by Schneider-Revueltas et al. onlinelibrary.wiley.com/doi/10.1002/...
21.08.2025 12:23 β π 9 π 8 π¬ 1 π 1
EJI & EFIS are proud to announce the brand-new ECR Article of the Year Award π
Presented by EJIβs Editor-in-Chief Matteo Iannacone at #IUIS2025, this prize celebrates outstanding research by early career researchers published in EJI π
Check the eligibility criteria hereπ
bit.ly/3Hvn9t5
20.08.2025 08:43 β π 14 π 7 π¬ 1 π 0
Thanks for sharing @brendaraud.bsky.social and @immunologypodcast.com!
21.08.2025 06:22 β π 5 π 0 π¬ 0 π 0
π’ Call for papers! Our special issue on Autoimmunity & Environmental Factors is open for submission.
β
Guaranteed peer review for all #IUIS2025 participants!
Contribute to advancing our understanding of how modifiable factors influence immune tolerance and autoimmunity π bit.ly/3HFEgIA
19.08.2025 07:05 β π 6 π 3 π¬ 1 π 0
Editor-in-Chief Nadja Bakocevic presenting at #IUIS2025 Career Fair on the ways @eurjimmunol.bsky.social and @efis-immunology.bsky.social support early career researchers.
β¨ Celebrating 50 years of EJI and introducing the brand-new ECR Article of the Year Prize!
18.08.2025 13:46 β π 4 π 3 π¬ 2 π 0
π¬ #EFIS will be at the #IUIS2025 exhibition hall!
Come say hello, discover our programs, network with fellow immunologists, learn about EJI prizes, and grab some treatsβ¨
π
Aug 17β21 | π Booth # 42
#Immunology
@eurjimmunol.bsky.social @yefis-immunology.bsky.social
15.08.2025 12:29 β π 6 π 3 π¬ 1 π 0
π’ EJI is at #IUIS2025 in Vienna!
Come meet us at the EFIS booth #42 π
Weβd love to hear about your science, answer your publishing questions, and connect with the global immunology community π¬π
See you there! π
@yefis-immunology.bsky.social @efis-immunology.bsky.social @iuis-online.bsky.social
18.08.2025 12:05 β π 19 π 8 π¬ 1 π 0
Do not miss it! π
14.08.2025 12:35 β π 3 π 0 π¬ 0 π 0
What can I say... my watercolor made it to the cover of the latest issue of @natimmunol.nature.com, together with our paper on IL-27 in chronic hep B π We really put the cherry on top in the @iannaconelab.bsky.social @cristianbeccaria.bsky.social. π₯Ήπ Check it out! www.nature.com/ni/volumes/2...
01.08.2025 14:59 β π 20 π 2 π¬ 2 π 1
Venzin and Beccaria et al. demonstrate that pre-activated CD4+ T cells actively license local hepatic APCs and restore antiviral CD8+ T cell function. bit.ly/4kRAbhS Β βͺ@valentinavenzin.bsky.socialβ¬ Β @cristianbeccaria.bsky.socialβ¬ Β βͺ@iannaconelab.bsky.socialβ¬
24.07.2025 15:30 β π 5 π 2 π¬ 0 π 0
Located at the Center of Molecular Biology of Inflammation (ZMBE) our research aims at understanding single cell and population dynamics in immune cells - with a special focus on visualizing subcellular aspects with all forms of microscopy.
Ophthalmologist. Comedian. Speaker. Jonathan.
Assistant Professor - Liver immunology - Imperial College - https://www.triantafylloulab.com/
Non-for-profit publication of research in molecular, cell & organismal biology - as part of @embopress.org
Fast-fair-transparent / Open Access / Open Science
EMBO Fellow at IannaconeLab | San Raffaele Scientific Institute
B & T cell immunologist π¬
Poetry lover, kinda musician, WIP photographer, someday filmmaker β€οΈβπ₯
Exploring the intersection of science, art, and humanity π
World is for everyone! π³οΈβπβπΌ
EMBO is the organization of more than 2,100 leading researchers that promotes excellence in life sciences in Europe and beyond.
https://www.embo.org/
Non-profit publisher of @embojournal.org, @emboreports.org, @embomolmed.org, @molsystbiol.org and @lsajournal.org. #OpenScience #Policy
Nature Immunology publishes original research, reviews and commentary of the highest quality and significance in all areas of immunology.
Nature Reviews Cancer is a monthly review journal for researchers working on cancer. We, the editors, highlight the most exciting topics in cancer research.
https://www.nature.com/nrc/
Publishing the best of biotech science and business. Find us on Twitter, Facebook & Instagram. Part of @natureportfolio.nature.comβ¬.
Journal of Experimental Medicine publishes immunology, cancer, stem cells, microbial pathogenesis, vascular biology, and neurobiology research. Published by Rockefeller University Press @rupress.org
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Associate editor Science Magazine
Immunology | Haematology | Host-pathogen interactions
Cutting-edge research in immunology from around the world, and commentaries by thought leaders. Cell Press. Tweets by Immunity editors.
We're a research lab at Rockefeller University (NY) and Necker Hospital (Paris) studying human genetic and immunological determinants of infectious diseases.
https://www.hgid.org/
Cell aims to publish the most exciting and provocative research in biology. Posts by Scientific Editors on the Cell editorial team. See the latest papers at https://www.cell.com/cell/
Deputy Editor at Journal of Experimental Medicine, interested in host-pathogen interaction, innate immunity and beyond. Opinions are my own.
π΄σ §σ ’σ ³σ £σ ΄σ Ώ Cytokines Parasites
Research, news, and commentary from Nature, the international science journal. For daily science news, get Nature Briefing: https://go.nature.com/get-Nature-Briefing
Passionate about #immunology. Sensing damaged self, infections & microbiota by DCs and macrophages to ignite innate & adaptive immunity. #Immunometabolism
Professor of Immunology @CNIC, Madrid, Spain. https://www.cnic.es/en/investigacion/immunobiology
