Debabrata Laha

The cover of the December issue. The cover depicts a SEM image of a dorsal surface of liverwort M. polymorpha female thallus. Liverwort were found to have a noncanonical pathway for the regulation of master growth repressor DELLA.

Our November issue is live!

www.nature.com/nchembio/vol...

The cover depicts a SEM image of a dorsal surface of liverwort M. polymorpha female thallus. Liverwort were found to have a noncanonical pathway for the regulation of master growth repressor DELLA.

31.10.2025 14:00 — 👍 5    🔁 1    💬 0    📌 1

Really delighted and humbled to see that we made it into cover! This is first time for us. Please see more details about work in PMID: 40745478.

31.10.2025 16:27 — 👍 0    🔁 0    💬 0    📌 0

We are grateful to the editor and reviewers for their critical and constructive feedback that strengthened our conclusion.

11.09.2025 18:25 — 👍 0    🔁 0    💬 0    📌 0

Conservation of heat stress acclimation by the IPK2-type kinases that control the synthesis of the inositol pyrophosphate 4/6-InsP7 in land plants Author summary Inositol pyrophosphates (PP-InsPs) are eukaryote-specific cellular messengers that control a plethora of critical physiological processes, ranging from cellular metabolism to cellular e...

Happy to share our work on identification of non-archetypal activity of IPK2 in producing inositol pyrophosphate 4/6-IP7 and regulating heat stress acclimation-conserved in studied land plants. Grateful to @jessenlab.bsky.social for wonderful collaborative efforts!

journals.plos.org/plosgenetics...

11.09.2025 18:25 — 👍 7    🔁 4    💬 1    📌 0

GA-independent DELLA regulation by inositol pyrophosphate in a nonvascular land plant - Nature Chemical Biology A noncanonical pathway of DELLA regulation by a conserved inositol pyrophosphate synthase was identified in the liverwort, Marchantia polymorpha, that lacks the canonical gibberellin-induced DELLA deg...

Delighted to share our work "GA-independent DELLA regulation by pyrophosphate in a nonvascular land plant" published now in Nature Chemical Biology! @natchembio.nature.com

www.nature.com/articles/s41...

31.07.2025 10:25 — 👍 7    🔁 2    💬 0    📌 0

Expanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP‐InsP4 Isomers in Plant Signaling Inositol pyrophosphates (PP-InsPs) are highly phosphorylated signaling molecules that regulate diverse cellular processes, including phosphate homeostasis and energy metabolism across species. Despit...

congrats to Kevin! His paper on new inositol pyrophosphates is out in @angewandtechemie.bsky.social

doi.org/10.1002/anie...

01.07.2025 16:01 — 👍 10    🔁 2    💬 2    📌 0

Congratulations Henning, Kevin, Gabriel and team!

01.07.2025 17:39 — 👍 1    🔁 0    💬 0    📌 0

Stereoselective chemoenzymatic phytate transformations provide access to diverse inositol phosphate derivatives Phosphorylated myo-inositols (InsPs) are essential cytoplasmic signaling molecules, while their lipidated analogs (PtdInsPs) play a crucial role in membrane signaling. Stereoselective synthesis of the...

An alternative strategy to access inositol derivatives by stereoselective dephosphorylation. Happy to share the work by Markus Haener together with @gabrielschaaf.bsky.social and many others.
chemrxiv.org/engage/chemr...

18.04.2025 11:05 — 👍 4    🔁 3    💬 0    📌 0

The final version of our study on SERK-BIR module in Marchantia is out.

Congratulations Cate and many thanks to collaborators!

www.sciencedirect.com/science/arti...

17.04.2025 15:23 — 👍 52    🔁 27    💬 7    📌 1

Expanding the PP-INSP₄ Toolbox: Synthesis, Stereochemical Assignment, and Application in Plant Phosphate Signaling Inositol pyrophosphates (PP-InsPs) are highly phosphorylated signaling molecules that regulate diverse cellular processes, including phosphate homeostasis and energy metabolism across species. Despite...

Happy to share Kevin´s great work on PP-InsP4 synthesis and analysis now available on Chemrxiv!

chemrxiv.org/engage/chemr...

28.03.2025 13:38 — 👍 4    🔁 1    💬 0    📌 0