ProteomicsNews (Ben Orsburn)

Wait. The “Pokémon at 30” article counts as research?

Tribidictable?

I’m interpreting this week’s events as the uncle of 2x 16 year old boys who don’t get B’s in West Virginia public schools. First week out of summer break I’m taking everyone to OBX to be a good influence and buy them stuff in case their dumb asses sign up for a holy war for morons. No ASMS for me.

*CAN for Microsoft users and dyslexic/dysgraphic?

Like a Lindsay Pinot?

Time to fill a room underground with Riojas…

Job hunting this morning, looking at anything in UK, France, Netherlands, Germany, Switzerland... So far not much options. Probably need to start calling in favours.

…my first name generally isn’t the one people have problems with…

@ypriverol.bsky.social can probably help. I only know of one olink repository, but I remember him saying they had several, but maybe it isn’t streamlined yet?

The TMT on a TimsTOF paper was rejected 6 times. Half of those were because “MS3 is necessary for good quan.” The other half was because the first author is a mediocre scientist and writer. He was worse then.

I handed in my keys to my labs to Johns Hopkins at 2pm and my email was GONE by 8am the next day. It was life altering but it reinforced that leaving was the right decision. Program officers love their emails bouncing. It makes a place seem kind, organized and professional.

Here it comes! The “you never actually needed MS3 to do multiplexing, y’all are just so bad at math that we made $3 billion selling you slow ass instruments and retarding the development of proteomics as a field” paper #1!

Exclusive: Read the draft executive emergency order for Trump to take control of elections Lawyers and legal experts explicitly said that such an order is blatantly unconstitutional.

EXCLUSIVE: A draft executive order that would allow Trump to take unprecedented control over federal elections is reportedly being circulated with the White House.

Democracy Docket obtained a copy.

Read the full, 17-page order below👇

scProfiterole: Clustering of Single-Cell Proteomic Data Using Graph Contrastive Learning via Spectral Filters www.biorxiv.org/cont...

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#proteomics #prot-preprint

I think it’s smart to have overlapping bins like DIA on non-segmented quads…?

a girl in a red sweater says " i want it now " ALT: a girl in a red sweater says " i want it now "

Free ChatGPT gets super snarky about delivering prime numbers in 10,000 number bins. If you really need the first 100 billion right now there probably is no easy option. 🦞🦀

WTF….?

Right?? Hey Klaude! Let’s go!

Wait. Can we now publish proteomics data in Analytical Chemistry without depositing the data or are the editors and reviewers all asleep in this upcoming issue?

I have an older version I run locally on LLM Studio. It’s physically sandboxed and doesn’t know it. On an M4 with 24GB it runs as fast as the service I used to pay for.

Reddit has a proof of cancellation of OpenAI subscriptions with almost 1,000 posts in the last 8 hours. I guess there are ethic questions about Anthropic as well but I ain’t paying a monthly fee to train an AI for war.

Related, and there is reason to believe that this has gotten worse rather than better. research.kpchr.org/News/Press-R...

Top-down proteomics of....skinned...human....wait. what? Ummm.... Wish I'd seen this before US HUPO, because I clearly had an opportunity to ask some questions this week of the PI!  Silliness asi...

The lack of sunlight is starting to get to them in Wisconsin, I think. Get a S.A.D. light and Vitamin D supplements (from a Doctor and pharmacy!! The over the counter ones in the US are NOT accurate and that dose does matter.) proteomicsnews.blogspot.com/2026/02/top-...

Truly the year of Seattle proteomics!! University of Washington Genome Sciences department almost had a clean sweep!! 💪🏆

YES!!!

I’d like you all to know I’m growing as a person. I didn’t go to the #USHUPO somascam breakfast seminar to point out yet again that every other technology here can estimate protein concentration changes.

Were you at #USHUPO2026 and saw Ben @proteomicsnews.bsky.social and Renã Robinson with Natalie Clark @nmclark2.bsky.social for a LIVE recording of #THEProteomicsShow? Well, I wasn't either, but we now we can bathe our ears in this audio. Find it wherever you find podcasts. anchor.fm/theproteomic...

#USHUPO - you can still pitch your lab to get CVs from the amazing pool of ECRs here this (Tuesday) evening! It’s so worth it. Post your interest on the app, drop by or ask a student researcher. Can’t find them? @amandalsmythers.bsky.social and I can help!

Thank you all for the first Whova badge for highly attended seminar!