@proteomicsnews.bsky.social
Assistant Professor at the University of Pittsburgh. What?? Previous industry CSO. Proteomics researcher with time consuming hobbies in scientific outreach. Opinions are often loud and exclusively my own. www.proteomics.rocks (he/him/his/dude)
This is an annoying way to watch basketball but it’s less annoying than giving Jeffy Bozo $16.99 a month and it’s better than watching on a 640 x pixel RGB monitor in college. Relative annoyance.
Somebody listed a QE HFX on EBay with a $2.1M buy it now price. Lost track of zeroes?
In 2026 if we need a good spectral library for a weird tough sample do we still run the HPH fractions with DDA? That was my default for compatibility with more tools, but I’d appreciate other opinions.
I'm continually surprised when I just plug a PTM into modern global DDA proteomics data search and - boom - there's a pile of peptides with that PTM that make sense. I worry students will miss out hand rocking 4kg of peptides with $30k in mABs in a walk in 4C for 20 hours to find 3 acetylations.
Wait. The “Pokémon at 30” article counts as research?
Tribidictable?
I’m interpreting this week’s events as the uncle of 2x 16 year old boys who don’t get B’s in West Virginia public schools. First week out of summer break I’m taking everyone to OBX to be a good influence and buy them stuff in case their dumb asses sign up for a holy war for morons. No ASMS for me.
*CAN for Microsoft users and dyslexic/dysgraphic?
Like a Lindsay Pinot?
Time to fill a room underground with Riojas…
Job hunting this morning, looking at anything in UK, France, Netherlands, Germany, Switzerland... So far not much options. Probably need to start calling in favours.
…my first name generally isn’t the one people have problems with…
@ypriverol.bsky.social can probably help. I only know of one olink repository, but I remember him saying they had several, but maybe it isn’t streamlined yet?
The TMT on a TimsTOF paper was rejected 6 times. Half of those were because “MS3 is necessary for good quan.” The other half was because the first author is a mediocre scientist and writer. He was worse then.
I handed in my keys to my labs to Johns Hopkins at 2pm and my email was GONE by 8am the next day. It was life altering but it reinforced that leaving was the right decision. Program officers love their emails bouncing. It makes a place seem kind, organized and professional.
Here it comes! The “you never actually needed MS3 to do multiplexing, y’all are just so bad at math that we made $3 billion selling you slow ass instruments and retarding the development of proteomics as a field” paper #1!
EXCLUSIVE: A draft executive order that would allow Trump to take unprecedented control over federal elections is reportedly being circulated with the White House.
Democracy Docket obtained a copy.
Read the full, 17-page order below👇
scProfiterole: Clustering of Single-Cell Proteomic Data Using Graph Contrastive Learning via Spectral Filters www.biorxiv.org/cont...
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#proteomics #prot-preprint
I think it’s smart to have overlapping bins like DIA on non-segmented quads…?
Free ChatGPT gets super snarky about delivering prime numbers in 10,000 number bins. If you really need the first 100 billion right now there probably is no easy option. 🦞🦀
WTF….?
Right?? Hey Klaude! Let’s go!
Wait. Can we now publish proteomics data in Analytical Chemistry without depositing the data or are the editors and reviewers all asleep in this upcoming issue?
I have an older version I run locally on LLM Studio. It’s physically sandboxed and doesn’t know it. On an M4 with 24GB it runs as fast as the service I used to pay for.
Reddit has a proof of cancellation of OpenAI subscriptions with almost 1,000 posts in the last 8 hours. I guess there are ethic questions about Anthropic as well but I ain’t paying a monthly fee to train an AI for war.
Related, and there is reason to believe that this has gotten worse rather than better. research.kpchr.org/News/Press-R...
The lack of sunlight is starting to get to them in Wisconsin, I think. Get a S.A.D. light and Vitamin D supplements (from a Doctor and pharmacy!! The over the counter ones in the US are NOT accurate and that dose does matter.) proteomicsnews.blogspot.com/2026/02/top-...
Truly the year of Seattle proteomics!! University of Washington Genome Sciences department almost had a clean sweep!! 💪🏆
YES!!!