Boca Scientific Inc.

We are thrilled to be attending #Neuroscience2025 in San Diego, CA! Visit us November 16-19 at booth 2415 to learn about our extensive product offerings, including our Home Cage Analyzer for 24/7 rodent behavior monitoring with welfare benefits!

Visit us: bocascientific.com

See it on our website: bocascientific.com/products/hom...

#SafetyPharmacology #Toxicology #DrugDiscovery #Neuroscience #3Rs #TranslationalScience #BehaviouralScience #HomeCageMonitoring #PreclinicalResearch #AnimalWelfare #DataDrivenScience #ActualAnalytics

We are excited to share a landmark, multi-company validation showing home-cage monitoring detects CNS safety signals missed by traditional Irwin/FOB testing. Home Cage Analyzer offers welfare benefits, & increased sensitivity for 24/7 data capture.
www.frontiersin.org/.../ftox.202...

A group from @ucsandiego.bsky.social discovered the gut's rhythmic muscle movements could explain how blood vessels in the brain expand & contract. Their findings could help scientists understand brain function & digestive issues. #Neuroscience #Gastroenterology
journals.aps.org/prl/abstract...

Happy Halloween from Boca Scientific Inc! 🎃👻

Single antivenom protects against 17 different snakebites Researchers immunized an alpaca and a llama with snake venoms, and combined some of the antibodies produced into a potent cocktail.

Researchers have created an antivenom using #antibodies from both a llama and an alpaca, that is able to neutralize venom from some of the worlds most venomous snakes. The treatment provided protection against toxins from 17 African snake species.

www.nature.com/articles/d41...

Researchers have identified a previously unknown #genetic disease that affects movement & muscle control. Mutation in NAMPT Axonopathy (MINA) syndrome causes damage to motor #neurons, ultimately resulting in #cells not producing enough energy.
www.science.org/doi/10.1126/...

Leucine-rich α-2-glycoprotein 1 initiates the onset of diabetic retinopathy in mice LRG1-driven microvascular dysfunction triggers early diabetic retinopathy, highlighting a potential therapeutic target.

A study from @ucleye.bsky.social has identified a key #protein that triggers diabetic retinopathy. The protein LRG1 is the cause of the early damage and targeting this could offer a way to protect vision. #Ophthalmology
www.science.org/doi/10.1126/...

Our SK-1S and BEK-50 were used in a study investigating whether variation in the serotonin transporter #gene (5-HTTLPR) influences response to attentional bias modification (ABM) in depression.
See the products here: bocascientific.com/products/dna...

www.nature.com/articles/s41...

Breastfeeding boosts immune cells that protect against breast cancer The protective, long-lived T cells can persist for decades after a woman gives birth.

Researchers at @petermaccc.bsky.social found pregnancy and breastfeeding induce the accumulation of specialized #immune cells that reduce the chances of breast #cancer developing, as the breast remodels itself to create milk to help a baby's organs, brain, and bones.
www.nature.com/articles/d41...

Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest Galeano Niño et al. show that extracellular bacteria dominate colorectal and oral tumor microniches, remodeling the microenvironment with reduced cell density, scattered epithelium, and low proliferat...

In a study led by @mdanderson.bsky.social, researchers found that the #bacteria, Fusobacterium nucleatum, can induce a reversible state in #cancer epithelial #cells. Tumors then can evade the immune system and resist chemotherapy. #CancerResearch

www.cell.com/cancer-cell/...

Faulty mitochondria cause deadly diseases: fixing them is about to get a lot easier CRISPR-based tools can’t easily access the DNA in these organelles, but researchers are finding other ways in.

In a new study, researchers have been looking for ways to edit the mitochondrial #genome. Unfortunately, #CRISPR gene editing cannot easily reach the mitochondria, forcing researchers to find another way to edit the genome & treat/cure #genetic conditions.
www.nature.com/articles/d41...

Highly sensitive monitor can detect vitamin B6, glucose in sweat | Penn State University A team of researchers led by Huanyu “Larry” Cheng, the James L. Henderson, Jr. Memorial Associate Professor of Engineering Science and Mechanics, created an on-skin sensing platform to detect vitamin ...

Researchers @pennstateuniv.bsky.social developed a noninvasive skin sensing platform to detect vitamin B6 in sweat. Some patients with #diabetes might experience low concentrations of vitamin B6, making this device important for those who are more vulnerable.
www.psu.edu/news/enginee...

Our new DNA Polymerases, Master Mixes, and Reagents from Medix Biochemica are a great edition to your #PCR workflows. These products deliver exceptional reliability, sensitivity, and flexibility, with customizable enzyme characteristics! #DNA
See them: bocascientific.com/products/pcr...

Antimicrobial resistance (#AMR) is projected to cause 39 million deaths worldwide over the next 25 years. This data is caused by the scarcity of drugs in development and lack of new methods to fight drug-resistant #bacteria. #antiboticresistance

www.nature.com/articles/d41...

Single-cell atlas of cervical organoids uncovers epithelial immune heterogeneity and intercellular cross-talk during Chlamydia infection Organoids and single-cell analysis uncover diverse cervical epithelial immune strategies to fight infection.

New research led by a team at @au.dk has found that cervical #epithelial cells play an active role in fighting infections. They used #organoids and single-cell mapping to show how these cells in the cervix detect and respond to infection.

www.science.org/doi/10.1126/...

Our news-worthy liquid plate sealer is used for stabilizing coated ELISA plates, immunochromatographic test strips, affinity chromatography columns, protein arrays and other applications. This stabilizer improves the reliability of the #assay!

See it: bocascientific.com/837-160-500-...

A cysteine-rich diet may promote regeneration of the intestinal lining, study suggests A diet rich in cysteine has rejuvenating effects in the small intestine, according to a new study. The amino acid can turn on an immune signaling pathway that helps stem cells regrow new intestinal ti...

A study from MIT, found a diet rich in the amino acid cysteine, may have rejuvenating effects in the small intestine. This amino acid causes regeneration, helping #StemCells regrow new tissue to help heal injuries from radiation. #Gastroenterology

Our SD Polymerase was used in a study applying Circular- and Linear-Amplicon-Mediated Error Correction to boost Nanopore sequencing, for high-fidelity viral genome sequencing from wastewater & marine #virus samples.
bocascientific.com/981-108910-d...
advanced.onlinelibrary.wiley.com/doi/10.1002/...

How to get the best night’s sleep: what the science says Chuck the gadgets, the fads and the alarm. Circadian research reveals how important your body’s internal clock is to blissful slumber.

Read scientists advice below, based on circadian rhythm research, on how to achieve the best nights sleep! For better sleep they advise contrasting light and dark, consolidating mealtimes and keeping sleep times consistent.
www.nature.com/articles/d41...

Assessing cerebral microvascular volumetric with high-resolution 4D cerebral blood volume MRI at 7 T - Nature Cardiovascular Research Guo, Zhao and colleagues use high-resolution 7 T MRI to measure the pulsatility of cerebral small vessels and uncover age-related differences in vascular dynamics, which offer new insights into mechanisms of brain aging and vascular risks.

In a new study from @keckschoolusc.bsky.social, a new brain imaging technique revealed how blood vessels in the brain pulse with each heartbeat, offering clues to aging and #Alzheimers disease. #cardiology

www.nature.com/articles/s44...

We are excited to be exhibiting at Neuroscience 2025! Join us in San Diego, CA November 16-19th to learn about our extensive product offerings to enhance your neuroscience research. We look forward to meeting you at booth# 2415! @sfn.org #Neuroscience

Multivariate genome-wide association analysis of dyslexia and quantitative reading skill improves gene discovery - Translational Psychiatry Translational Psychiatry - Multivariate genome-wide association analysis of dyslexia and quantitative reading skill improves gene discovery

Researchers have conducted the largest #genome study exploring the #genetic underpinnings of dyslexia. Their goal was to uncover new genes linked with dyslexia and insight into the biological basis of differences in reading ability.

www.nature.com/articles/s41...

Lymph nodes fuel KLF2-dependent effector CD8+ T cell differentiation during chronic infection and checkpoint blockade - Nature Immunology Here the authors show a function for lymph nodes in the maintenance of effector T cell differentiation and function during chronic infection and checkpoint blockade, identifying a spatial component in...

In a new study from @thedohertyinst.bsky.social, researchers explored the #cellular and #molecular interactions of lymph nodes and the fight against infection and #cancer. Lymph nodes allow #T-Cells to multiply and produce killer cells that can fight cancer.
www.nature.com/articles/s41...

Our antibody stabilizer was used to show that #immune cell dynamics are a potential driver of therapy response in metastatic #Melanoma. #Immunology

See it here: bocascientific.com/106-131-52-d...

www.nature.com/articles/s41...

Researchers identify new method to protect against sepsis A team of University of Saskatchewan (USask) researchers have identified a pathway to help the human body defend itself against sepsis—a life-threatening condition caused by the body's inappropriate r...

Researchers @usaskmed.bsky.social have identified a #protein pathway to help the human body defend against #sepsis. Sepsis is the number one cause of death in the intensive care unit of hospitals worldwide, a major concern for medical professionals.
medicalxpress.com/news/2025-09...

Local photocrosslinking of native tissue matrix regulates lung epithelial cell mechanosensing and function - Nature Materials Using visible-light-induced crosslinking, a local stiffening approach is developed for ex vivo mouse and human lung tissue as an early lung injury model, directing epithelial cell mechanosensing, diff...

A collaborative study spanning universities in the US, has found that changes in the mechanical environment of lung tissue, might set off a chain reaction leading to #fibrosis. Their hope is to better predict who is at risk and when to best provide care!

www.nature.com/articles/s41...

Single Hair Strand Could Provide Biomarker for ALS, Mount Sinai Study Finds

A new study from Icahn School of Medicine at Mount Sinai, found that a single strand of hair can show elemental patterns that distinguish people with #ALS from healthy individuals. This test could potentially speed up ALS diagnosis and improve care.
www.mountsinai.org/about/newsro...

A mammoth toothache: bacterial community discovered in mouth of ancient mammal Genetic-sequencing techniques have uncovered the oldest host-associated microbial DNA ever recorded — inside samples of teeth and bones from woolly and steppe mammoths.

Researchers @cpgsthlm.bsky.social have identified the oldest #microbial DNA ever sequenced, through analyzing the bones and teeth of ancient mammoths. This reveals species of pathogenic #bacteria or #viruses that could have contributed to extinction.

www.nature.com/articles/d41...

We are so excited to meet you September 10th-12th in Columbus, Ohio at #analyticaUSA. Contact us to learn more about our FREE 3-day passes!