International Journal of Particle Therapy

Fig. 1. Representative color wash images in axial (left), coronal (middle), and sagittal (right) planes comparing protons (top row) versus photon (bottom row) based SBRT dose deposition for primary RCC. As shown, the target receives similar coverage in the two planes, with greater sparing of nearby structures with protons including the healthy part of the kidneys, stomach, bowel and liver.

In press now: #kidneycancer represents 4% of all new #Cancer cases in the US. Read a study that suggests #Proton based #SBRT improves target coverage while reducing the dose to primary renal cell carcinoma patient OARs: www.sciencedirect.com/science/arti...

Fig. 1. Diagram of the proton clinic RTLS sensors/zones. The colors indicate room status (green for available and yellow for occupied).

Numerous factors influence #protontherapy treatment times & with 29 new centers opened in the last 5 years, #NAPT reports these patients have tripled. Read treatment time insights from the Miami Cancer Institute’s RTLS system #RTLS system - www.sciencedirect.com/science/arti... #cancer #radonc

Fig. 2. Treatment plan review workflow incorporating Auto-IniCheck for initial plan assessment. Auto-IniCheck is integrated into the initial plan review process for dosimetrists and physicists to enhance error detection and improve review efficiency. The figure illustrates the use of Auto-IniCheck with manual checks, streamlining the initial review process.

In press now: Read a UF Health Proton Therapy study that developed & validated an automated framework for #protontherapy plan review, enhancing error detection capabilities & workflow efficiency in pencil beam scanning: www.sciencedirect.com/science/arti... #PBS #radonc #MedPhys #cancerresearch

Fig. 1. Alignment Issue Caught by CBCT. In both the CBCT and the QACT, the alignment is to the fiducials and it can be observed that the bony anatomy is then very off. This resulted in an adaptive plan. This highlights the usefulness of CBCTs in identifying patient anatomical changes that can reduce the standard QACT rates, instead triggering a QACT if anatomical changes, such as this bony vs fiducial alignment difference, are observed on CBCTs.

Excessive quality assurance computed tomography scans can increase patient burden, resources, & #healthcare costs. Read a John Hopkins School of Medicine study evaluating the impact of standardized minimum #QACT frequencies across treatment sites - sciencedirect.com/science/arti... #MedPhys #Cancer

Figure 1. Experimental Materials. Figure 1A shows how differentiation is induced in MC3T3-E1 and RAW264.7 cells. Figure 1B illustrates the method of verifying the bystander effect and the structure of the items used for the experiment. Abbreviations: RANKL = receptor activator of nuclear factor kappa-B ligand.

In press now: Read a collaborative Juntendo-Harvard study that suggests both #Xrays and #protons may induce #radiation-induced bystander responses in osteoblasts and osteoclasts, irrespective of cell combination, dose, or radiation type: www.sciencedirect.com/science/arti...

Volume 17 is online now! Read articles related to #IMPT Versus #IMRT for #BreastCancer, #Protons or #Photons in pituitary #neuroendocrine tumors, NTCP-based prediction of lung sparing with IMPT, and more: www.sciencedirect.com/journal/inte...

Fig. 3. Summed dose distribution of the two treatment plans Sum of the dose from external beam photon radiotherapy and carbon ion radiotherapy, expressed in EQD2.

Clear cell #adenocarcinoma of the uterine cervix is a rare and aggressive subtype of #cervicalcancer, typically resistant to conventional #RT. Read a case report in press with IJPT that suggests a #CIRT boost can achieve long-term local control: www.sciencedirect.com/science/arti... #cancerresearch

Thank you Dr. Deasy! As far as we know, there is no widely consolidated dataset that directly links cell cycle arrest with linear energy transfer (LET) in a clinical setting - would anyone else out there on Bluesky have information on this?

Fig. 5. Medras accurately predicts radiation response in different cell models, shown by the correlation between Medras-predicted and experimentally obtained MID values.

Understanding how cells respond to & repair DNA damage is crucial for optimizing #radiotherapy - a new study evaluates how loss of different #DNA DSB repair genes impacts radiosensitivity: www.sciencedirect.com/science/arti... #MedPhys #RadOnc #ParticleTherapy #CancerResearch #protontherapy

Registration is now open for the #PTCOG-NA 11th Annual Meeting in Shreveport November 7-9, 2025. Take advantage of Early Bird Rates until August 20th! Learn more: www.ptcog-na.org/ptcog-na-11t...

Protons or Photons in Pituitary Neuroendocrine Tumors– That is Not the Question With the long-life expectancy of patients with pituitary neuroendocrine tumors (PitNETs), reducing long-term toxicity is essential to preserve quality…

In press with IJPT now: a collaborative Oslo University Hospital team investigates whether 2- or 3-field #PBT plans better spare #OARs than #VMAT: www.sciencedirect.com/science/arti... #MedPhys #RadOnc #ParticleTherapy #CancerResearch #protontherapy

Fig. 1. Experimental setup for the X-ray computed tomography polymer gel dosimeter (XCT-PGD). (a) Schematic diagram of the gel dosimeter in a cylindrical container placed inside an absorber. (b) Photograph of the actual setup on the treatment couch. The gel dosimeter is placed in an absorber and positioned using external lasers so that the center of its sensitive region aligns with the mechanical isocenter. The dosimeter is then secured in place with adhesive tape.

In press with IJPT - learn about a novel method using an #XCT-PGD with on-board #CBCT for comprehensive 3D verification of #proton beam delivery accuracy: www.sciencedirect.com/science/arti... #MedPhys #RadOnc #ParticleTherapy #CancerResearch

Volume 16 is complete & online now, featuring articles on #medulloblastoma from the Pediatric Proton/Photon Consortium Registry #PPCR, operational improvement of a #protontherapy system, & more: sciencedirect.com/journal/inte... #CancerResearch #radonc #MedPhys

From Fig. 1. The irradiation field diagrams of IMPT and IMRT (A) and illustration of cardiac substructures delineation, mean dose, and isodose line distribution for IMPT and IMRT in left-sided (B) and right-sided (C) patients. Note: The mean dose to cardiac substructures is measured in cGy(RBE).

In press now with IJPT: #IMPT vs. #IMRT provides excellent cardiac protection, particularly for left-sided IMNI and high-risk #breast cancer patients - learn more: www.sciencedirect.com/science/arti...

Fig. 1. Dosimetric Savings of 2 mm Plans. The dosimetric difference for each OAR clinical goal is shown for each patient.

In press now: Learn how a tailored #QACT schedule based on beam trajectory and target location reduces unnecessary imaging without compromising treatment accuracy in cranial #protontherapy : sciencedirect.com/science/arti... #particletherapy #radonc #MedPhys

IJPT #cancerresearch article highlighted by U.S. News and World Report: www.usnews.com/news/health-...

Fig. 1. Angular distribution of gantry angle vs. selected beam energy and number of protons per control point for SPArc-step&shoot and SPArc-dynamic.

Learn about the development of #step-and-shoot arc therapy (SPArc-step&shoot) for #headandneck #cancer treatment @BeaumontRadOnc @CorewellHealth - in press now with IJPT: www.sciencedirect.com/science/arti... #RadOnc #protontherapy

Are you working on #AI applications in #ParticleTherapy? Learn more about our AI in PT Special Issue! Submission deadline is August 31, 2025, with publication at the close of 2025: www.sciencedirect.com/special-issu...

Join #PTCOG-NA for gumbo, gators and gantries! Abstract submission now open for the 11th Annual Meeting Nov 7-9, 2025 in Shreveport, LA. Deadline for submission is May 12th: www.ptcog-na.org/ptcog-na-11t...

Fig. 1. A pectoral myositis and dose distributions of C-ion RT.

#carbonion #radiotherapy is an emerging non-surgical treatment for early-stage #breastcancer - read the first study to evaluate pectoral myositis after C-ion RT, in press with IJPT now: www.sciencedirect.com/science/arti...

Figure 1. Schematic proposal of NTCP-based MBS in Italy and interplay between the variables involved.

In Italy, where 3 facilities are dedicated to #protontherapy and others are planned, definitive selection guidelines for #headandneck #cancer patients have yet to be established. Read an analysis of a model-based selection strategy in this landscape: www.sciencedirect.com/science/arti...

Volume 15 is online! Read about the value of #Hadrontherapy, #CarbonIon #RadiationTherapy, #radiomics for #PULSAR, and more: www.sciencedirect.com/journal/inte... #ParticleTherapy #CancerResearch #radonc #RadBio

63rd Annual PTCOG Conference | 2-7 June 2025 | Buenos Aires Welcome to the 63rd Annual PTCOG Conference—the leading event for particle therapy. Join us in Buenos Aires between 2-7 June 2025 to explore the latest breakthroughs in cancer treatment!

Mark your calendar for PTCOG 63 in Buenos Aires, June 2–7, 2025! Join experts and innovators from around the world to explore the latest in particle and proton therapy: ptcog63.org #PTCOG63

From figure 2B: IRO Approval Rate by State

In press now - Independent Review Organization appeals provide a valuable pathway to proton therapy access, with higher overturn rates improving significantly in recent years. Learn more: www.sciencedirect.com/science/arti...

Head & neck mucosal melanomas are aggressive, radiotherapy-resistant cancers-read about early outcomes of carbon-ion radiotherapy at #MedAustron for HNMM using European and Japanese RBE-adapted dose prescriptions: www.sciencedirect.com/science/arti... #melanoma #headandneck #cancer #cancerresearch

Fig. 1. The 4Rs of hadrontherapy indications: R-adioresistant, R-are, R-ecurrent, and R-adioinduced tumours. Figure made by iInkscape Project.

What is the role of hadrontherapy in treating radioresistant, rare, recurrent, and radioinduced tumors? Begin the new year understanding the '4Rs of hadrontherapy with an international, multidisciplinary team of experts and IJPT: www.sciencedirect.com/science/arti...

If you would like to be added to the radonc starter pack just let me know!

#radonc #radiotherapy #radiationoncology

go.bsky.app/2YKENEm

Volume 14 is online! Read about the value of #CarbonIon #RadiationTherapy for #BreastCancer, #Cardiac conduction as an OAR in #RadiationTherapy, #Proton vs #CyberKnife therapy for #ProstateCancer, and more: www.sciencedirect.com/journal/inte... #ParticleTherapy #CancerResearch #radonc #RadBio

Radiation Oncology Tag Ontology: Collaborative Design Integrating Hashtags Across Cancer Care In the five years since the patient-centered Cancer Tag Ontology (CTO) came into being, conversations about cancer on Twitter continue to grow. The

Radiation Oncology Tag Ontology [RTO]: Collaborative Design Integrating Hashtags Across Cancer Care [May 23, 2019] Matthew S. Katz, MD @subatomicdoc in @symplur blog ow.ly/9nNG30oOtaY #RadOntPro #radonc