Pierre Mattar

Woohoo!!!!

🔥

Fantastic! Congratulations!!!!

Mef2c Controls Postnatal Callosal Axon Targeting by Regulating Sensitivity to Ephrin Repulsion Intracortical circuits, including long-range callosal projections, are crucial for information processing. The development of neuronal connectivity in the cerebral cortex is contingent on ordered emer...

If you're interested in how Mef2c tunes neuronal response to repulsive guidance cues in the cortex, here's a link to the paper: www.jneurosci.org/content/45/2...

I loved your paper - it’s truly awesome!!!

Fantastic day!!!! Thanks Kristen and Monica!

Excluding the Genomic Location of Pax2 Regulatory Elements for the Developing Mouse Eye - PubMed The Pax2 transcription factor is activated uniformly in the optic vesicle/cup, but becomes progressively restricted to the forming optic disc and stalk. In the eye, it is not known how Pax2 expression...

So you want to study the optic nerve head. You’re thinking a Pax2-Cre driver should work, right? Well, think again: pubmed.ncbi.nlm.nih.gov/40300047/

Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels. Evolutionary adaptation to diurnal vision in ground squirrels has led to the development of a cone-dominant retina, in stark contrast to the rod-dominant retinas of most mammals. The molecular mechani...

Our latest manuscript (7 years in the works) tackles the question of how diurnal ground squirrels evolved a cone-dominant retina, in contrast to the ancestral rod-dominant retina retained by virtually all other mammals./1
www.biorxiv.org/content/10.1...

Hendrich Group - Starting Sept 2025 - Living Systems Institute - University of Exeter Opportunity for LSI PHD studentship – starting in September 2025 or January 2026 PhD Studentship applications will open on 1st...

Funded PhD Studentship available in my lab at @lsiexeter.bsky.social.
Want to study how chromatin remodellers act on enhancers to facilitate cell fate decisions in human pluripotent cells? Want to work and live in a lively city by the sea? Get in touch/Apply!
lsi.exeter.ac.uk/groups/hendr...

Congratulations!!! (Also yum!!)

I'm supporting Your Columbia! Your Columbia is your opportunity to be a part of the unparalleled research, education, and clinical care that takes place every day at Columbia University Irving Medical Center. It’s a potent and imp...

My lab studies mechanisms of pediatric glaucoma and the development of tissues affected (Schlemm's canal and trabecular meshwork). I am getting creative with fundraising because, well... So if you know someone who might be interested in funding our work: joinus.cuimc.columbia.edu/index.cfm?fu...

After injury some RGCs survive but do they thrive? In this collaboration with Jonathan Demb's lab (Yale), we looked into the physiology of resilient RGCs after axon injury. Their visual responses largely remain intact but they exhibit reduced intrinsic excitability, coincident with AIS disassembly.

Thanks for your interest! The thesis is not corrected yet. The initial data chapter was published already (www.nature.com/articles/s41...). We're hoping to preprint the bulk of the rest of the thesis in the coming few months.

Momentous day yesterday as Ivana Herrera successfully defended her doctoral thesis. Huge congratulations to her (seated center). Very proud of her!

UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

We’re hiring a new research fellow. Come join us in London to study glial cells in the ageing retina using killifish as a model. www.ucl.ac.uk/work-at-ucl/...

Congrats Michel and team (and Zack!!)

Jack this morning: It warm!!

Jealous!!!

Congrats Brian - and congrats to all the co-authors. Looks like a masterpiece!!!

First post on this platform is to announce that our preprint is posted to bioRxiv:

bioRxiv 2025.02.03.636318; doi: doi.org/10.1101/2025...

A black history flyer with a black background and brown fists in the air. Behind the black fists are red, yellow, and green stripes with the Black In Neuro logo at the top center.

Happy Black History Month ✊🏾

This month, as we do every month, we celebrate Black history and all the many accomplishments our people have made inside and outside of science.

We are all Black history yall. We love our community and wish you all joy and peace 🖤

💔

Looking for a high qualtiy scientific meeting being held in Canada this year? The 12th Canadian Developmental Biology Meeting (Regional SDB @socdevbio.bsky.social meeting) is happening May 25-28 in Kelowna BC. Registration is now open! www.sdbonline.org/meeting?Reso...

That’s my take fwiw

Gotcha! I’m telling you things you already know! But I think for us, it’s at least partly about the partition between primary sensorimotor vs. associative. Size doesn’t really change that ratio, which is partly why in humans, phrenology, male vs. female etc. is all total BS

Biggest brain in the animal kingdom: sperm whale. It’s about 5x bigger than ours’. Elephants have bigger brains than humans too. Both have much higher neuron counts, although we don’t think of them as smarter than us. Within our own brains, highest neuron numbers are in the cerebellum (by far).

Brindcy?

Establishment of terminal selector combinations in optic lobe neurons The medulla is the part of the Drosophila optic lobe with the greatest neuronal diversity, in which the identity of each neuronal type is specified in progenitors and newborn neurons via the integrati...

NEW PAPER ALERT! In this paper that was posted today on @biorxivpreprint.bsky.social, Felix Simon from our lab at @ijmonod.bsky.social (with important contributions by Isabel Holguera and a small contribution from yours truly) completed the trifecta. www.biorxiv.org/content/10.1...