Melina A. Agosto's Avatar

Melina A. Agosto

@agostolab.bsky.social

Assistant professor at Dalhousie University; retina cell biology and biochemistry, synapses, signaling, and trafficking; opinions are my own.

344 Followers  |  303 Following  |  32 Posts  |  Joined: 11.11.2024  |  1.9702

Latest posts by agostolab.bsky.social on Bluesky

@nclnoel.bsky.social studies aging retina in killifish and zebrafish

12.10.2025 16:48 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

But nice views of the wastewater treatment plant on approach!

01.10.2025 06:18 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Photo of gaskets for gel pouring rig (left) and roll of foam weatherstrip (right)

Photo of gaskets for gel pouring rig (left) and roll of foam weatherstrip (right)

Gel pouring rig with new gaskets :)

Gel pouring rig with new gaskets :)

We replaced the gaskets on the gel pouring rigs with foam weatherstrip a few months ago. No leaks yet!

30.09.2025 21:19 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

My department at Emory is a hiring a tenure-track neuroscientist!

Anyone who's talked to me in the last 4 years knows I cannot say enough good things about my dept and the neuroscience community here. My colleagues are so wonderfully supportive. Postdocs, please apply!

apply.interfolio.com/174371

30.09.2025 18:25 β€” πŸ‘ 133    πŸ” 104    πŸ’¬ 1    πŸ“Œ 5

WE ARE... hiring!

Penn State Biology & the Huck Institutes of the Life Sciences is recruiting a tenure track or tenured neurobiologist (Assistant or Associate Professor rank), and the committee is open to a broad scope of scientific questions.

psu.wd1.myworkdayjobs.com/PSU_Academic...

18.09.2025 09:56 β€” πŸ‘ 27    πŸ” 19    πŸ’¬ 1    πŸ“Œ 2
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Be our new colleague! πŸŽ‰
The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor.

πŸ‘‰ More details here: lnkd.in/e8Z9eAm4
πŸ‘‰ Our department: mocel.unige.ch

Please feel free to share this opportunity with your network.

15.09.2025 14:33 β€” πŸ‘ 42    πŸ” 49    πŸ’¬ 0    πŸ“Œ 1
Confocal microscope images of the outer plexiform layer of WT or nob3 (mGluR6 null) mouse retina labeled with antibodies for ELFN1 (cyan) and PSD95 (magenta). In nob3 retina, ELFN1 is still localized to rod spherules, but synaptic enrichment is compromised.

Confocal microscope images of the outer plexiform layer of WT or nob3 (mGluR6 null) mouse retina labeled with antibodies for ELFN1 (cyan) and PSD95 (magenta). In nob3 retina, ELFN1 is still localized to rod spherules, but synaptic enrichment is compromised.

New paper! Kudos to first author Jaeeun Lee, who is a fantastic and hard working student. We showed that at photoreceptor presynapses, ELFN1 enrichment depends on postsynaptic mGluR6.
www.jneurosci.org/content/earl...

11.09.2025 17:02 β€” πŸ‘ 15    πŸ” 6    πŸ’¬ 2    πŸ“Œ 0
Confocal microscope image of mouse retina section labeled with antibodies for PSD95 (magenta) and TRPM1 (green).

Confocal microscope image of mouse retina section labeled with antibodies for PSD95 (magenta) and TRPM1 (green).

The mysterious non-PSD localization of PSD95 🟣 in the retina outer plexiform layer... co-stained for postsynaptic TRPM1 🟒
#FluorescenceFriday

30.08.2025 22:10 β€” πŸ‘ 12    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Dean of Medicine Dalhousie University invites applications for the position of Dean, Faculty of Medicine. This is a pivotal leadership opportunity to shape the future of medical education, research, and healthcare acr...

Dalhousie University invites applications for the position of Dean, Faculty of Medicine. This is a pivotal leadership opportunity to shape the future of medical education, research, and healthcare across the Maritime provinces in Canada.
5 yr renewable appointment dal.peopleadmin.ca/postings/19319

27.08.2025 20:12 β€” πŸ‘ 6    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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Call for 20 Assistant Professor positions Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.

ki.se/en/about-ki/...

25.06.2025 14:56 β€” πŸ‘ 279    πŸ” 279    πŸ’¬ 1    πŸ“Œ 14
DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

10.06.2025 13:53 β€” πŸ‘ 112    πŸ” 162    πŸ’¬ 0    πŸ“Œ 8
A graph showing NIH funding for new and competitive renewal grants for FY2024 and FY2025 showing a much lower rate of investment for FY2025.

A graph showing NIH funding for new and competitive renewal grants for FY2024 and FY2025 showing a much lower rate of investment for FY2025.

I updated my funding curves last night.

Here are the results for new and competitive renewal grants.

The rate of investment has dropped substantially. This is apparently due to a requirement for DOGE review.

I am calling this effect the "Downward DOGE"

1/2

09.06.2025 10:50 β€” πŸ‘ 91    πŸ” 64    πŸ’¬ 4    πŸ“Œ 11
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Funding freeze at Northwestern from Emma Mairson at
grant-watch.us. Data from USAspending. Normally, ~$70 M per month. Now, bupkis.

Northwestern is keeping research moving and must be spending ~$40 M per month. Clearly not sustainable for too long.

07.06.2025 19:47 β€” πŸ‘ 224    πŸ” 106    πŸ’¬ 2    πŸ“Œ 5
Quote from MIT President Sally Kornbluth's commencement address: "We believe in the beauty and power of fundamental scientific discovery - that incredibly intricate, maddening, heroic, intoxicating process of exploration and testing that somehow got stuck with the bland label 'basic research.'"

Quote from MIT President Sally Kornbluth's commencement address: "We believe in the beauty and power of fundamental scientific discovery - that incredibly intricate, maddening, heroic, intoxicating process of exploration and testing that somehow got stuck with the bland label 'basic research.'"

Posted by @mit.edu on another platform

29.05.2025 22:22 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Wonder doesn’t flinch. It’s our compass pulling us toward curiosity, creativity It reminds us: #science & #discovery are good. Here’s a moment that stirred mine: a new PI(3,4)Pβ‚‚ probe illuminating the cell membrane & endosomes. Marvel with me. Captured on #FluorescenceFriday for #MicroscopyMonday

26.05.2025 16:43 β€” πŸ‘ 93    πŸ” 18    πŸ’¬ 6    πŸ“Œ 1
Retinal ON-bipolar cell expressing mEmerald-Sec61 (blue), and labeled with mGluR6 antibody (red).

Retinal ON-bipolar cell expressing mEmerald-Sec61 (blue), and labeled with mGluR6 antibody (red).

An elegant ON bipolar cell expressing ER marker mEmerald-Sec61 🟦 and co-stained with mGluR6 antibody πŸŸ₯. #FluorescenceFriday More info in this old paper: www.eneuro.org/content/5/3/...

02.05.2025 23:41 β€” πŸ‘ 18    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Have you ever seen the black box that is the inside of a microscope objective? Today Dr. Stephen Ross of Nikon gave a fascinating lecture on what goes into the design and manufacturing of an objective.

01.05.2025 18:16 β€” πŸ‘ 50    πŸ” 12    πŸ’¬ 1    πŸ“Œ 3
Eating lunch with some of my students

Eating lunch with some of my students

Lab lunch πŸ˜€

22.04.2025 20:37 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Assistant Professor (tenure track) – Chromatin, Epigenetics - Vancouver, British Columbia (CA) job with The University of British Columbia (UBC) | 12837841 Assistant Professor (tenure track) - Chromatin Regulation, Genetic Regulatory Mechanisms, Epigenetics, Epigenomics

www.nature.com/naturecareer... UBC LSI Job!!

04.04.2025 04:03 β€” πŸ‘ 32    πŸ” 36    πŸ’¬ 0    πŸ“Œ 2
Albert Einstein College of Medicine | Medical Education | Biomedical Research

FACULTY JOB ALERT! The Albert Einstein Dept of Neuroscience is hiring a new assistant professor in any area of neuroscience! We have funds specifically earmarked for this search. #Neuroscience #AcademicJobs #NeuroSky Job just posted: faculty-einstein.icims.com/jobs/17175/f... Please share widely!!

26.03.2025 17:52 β€” πŸ‘ 73    πŸ” 67    πŸ’¬ 1    πŸ“Œ 1

PIs and trainees in the US need to be supported now more than ever, not vilified. They are being targeted, and their work and livelihood are in jeopardy.

15.03.2025 20:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

as I tell my Genetics class every year, this breakthrough is based on 70 years of NIH-funded, basic research, commercialized by biotech
bsky.app/profile/need...

15.03.2025 18:49 β€” πŸ‘ 329    πŸ” 116    πŸ’¬ 3    πŸ“Œ 0
Graph between 1/20 and 2/28 of fiscal year 2024 and 2025 new awards in the EDU directorate.

Graph between 1/20 and 2/28 of fiscal year 2024 and 2025 new awards in the EDU directorate.

πŸ§ͺ🚨 NSF's Directorate for STEM Education (EDU) has halted making nearly all new awards since inauguration day.

Among *many* other things, EDU runs the Graduate Research Fellowship Program (GRFP).

We need to protect the education & training of the next gen of scientists #StandUpForScience

ThreadπŸ‘‡πŸ§΅

03.03.2025 13:55 β€” πŸ‘ 234    πŸ” 162    πŸ’¬ 2    πŸ“Œ 24

An excellent opportunity! And I'm not just saying that because I'll be teaching an imaging and comparative retinal anatomy workshop during this course 😁 πŸ‘€

Financial aid is available!

06.03.2025 20:58 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Thank you!

05.03.2025 19:06 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Photo of a sunset from the kitchen window in the retina lab at Dalhousie.

Photo of a sunset from the kitchen window in the retina lab at Dalhousie.

Submitted a new CIHR grant today. I don't suppose it will be funded, but I'm grateful to at least have a functional federal agency to submit it to. Also - sunset in the retina lab kitchen:

05.03.2025 18:43 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Welcome to Halifax! I moved here from Houston a few years ago.

05.03.2025 06:06 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Extending my grant update this morning. Here are data limited to new and competitive renewal applications.

The Pause is dead, Long live the Pause...

01.03.2025 11:47 β€” πŸ‘ 292    πŸ” 163    πŸ’¬ 12    πŸ“Œ 28
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a man in a red suit and tie is holding a piece of paper that says breaking news on it ALT: a man in a red suit and tie is holding a piece of paper that says breaking news on it

Some good-ish news from NIH

β€œFederal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again”

As far as I know, the timing for this is not clear, but I will be checking the Federal Register.

24.02.2025 16:38 β€” πŸ‘ 393    πŸ” 152    πŸ’¬ 17    πŸ“Œ 16

@agostolab is following 19 prominent accounts