Teddy Yewdell's Avatar

Teddy Yewdell

@tyewdell.bsky.social

B cells | plasma cells |autoimmunity | MS | IBD | lupus | immune memory | tiki taka | geggenpressing | Group Leader/Principal Scientist at Genentech https://www.gene.com/scientists/our-scientists/teddy-yewdell

218 Followers  |  311 Following  |  12 Posts  |  Joined: 26.02.2025  |  2.2745

Latest posts by tyewdell.bsky.social on Bluesky

Congrats to the Brown Lab!! Great fundamental question to tackle!, and Iโ€™m sure many fascinating discoveries to come!!

21.05.2025 20:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
A wave of Thetis cells imparts tolerance to food antigens early in life Within the intestine, peripherally-induced regulatory T (pTreg) cells play an essential role in suppressing inflammatory responses to food proteins. However, the identity of antigen-presenting cells (...

Excited to share our study describing a role for a subset of Thetis cells, TC IV, in tolerance to food antigens. A team effort led by Vanja Cabric and Yollanda Parisotto
www.science.org/doi/10.1126/...

21.05.2025 18:24 โ€” ๐Ÿ‘ 35    ๐Ÿ” 8    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

โ€œWe all said to each other, โ€˜This is the most significant thing we have ever done.โ€ An amazing story, and yet one that does not happen without federally funded basic research www.nytimes.com/2025/05/15/h...

15.05.2025 20:59 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Andor is really freaking me out - impeccable timing!

15.05.2025 06:16 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Opinion | I Came to Study Aging. Now Iโ€™m Trapped in ICE Detention.

'I did not complete a customs declaration for frog embryos (...) this would normally result in a warning or fine. Instead, my visa was revoked & I was sent to a detention center in Louisiana, where I have spent the past 3 months with roughly 100 other women. We share one room w dormitory-style beds'

14.05.2025 04:27 โ€” ๐Ÿ‘ 40    ๐Ÿ” 18    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 4

Just deranged. This was a *solved* problem.

02.05.2025 20:45 โ€” ๐Ÿ‘ 9237    ๐Ÿ” 2543    ๐Ÿ’ฌ 419    ๐Ÿ“Œ 143
Preview
Harvard University Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.

This is what scientific leadership and courage looks like:

www.harvard.edu

15.04.2025 03:14 โ€” ๐Ÿ‘ 143    ๐Ÿ” 29    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 1
Preview
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN Dr. Ardem Patapoutian says he watches โ€œwith deep sadness as the United Statesโ€™ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...

Published an op-ed for @cnn.com: โ€œNobel laureate: I owe America my success. Today, its scientific future is in danger.โ€
A personal reflection on whatโ€™s at stake as science funding gets slashed. Iโ€™d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...

09.04.2025 11:30 โ€” ๐Ÿ‘ 903    ๐Ÿ” 494    ๐Ÿ’ฌ 15    ๐Ÿ“Œ 25
Preview
The Brooklyn Stroll Club Has Brought Together Fathers in Search of Friendship For fathers in search of friendship, a growing group has emerged: the Brooklyn Stroll Club.

Love this, and also kinda sad we are done with strollersโ€ฆ Iโ€™m not crying, youโ€™re crying!!! www.nytimes.com/2025/04/12/s...

14.04.2025 01:54 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
a man wearing a mask is standing in a boxing ring and says take it eaassy ALT: a man wearing a mask is standing in a boxing ring and says take it eaassy

Leave some paper for the rest of us๐Ÿคฃ

05.04.2025 19:20 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Go @endicytosis.bsky.social!!! One more paper to go right!?!?

05.04.2025 16:06 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Opinion | The Uncertain Fate of the Young American Scientist (Gift Article) Young researchers are choosing between staying in science and staying in the United States.

www.nytimes.com/2025/04/03/o...

Really important piece to share widely. Too many Americans donโ€™t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security

04.04.2025 07:32 โ€” ๐Ÿ‘ 488    ๐Ÿ” 310    ๐Ÿ’ฌ 19    ๐Ÿ“Œ 57
Preview
Lung B cells in ectopic germinal centers undergo affinity maturation | PNAS The lungs are constantly exposed to the external environment and a myriad of antigenic challenges within the air. Chronic exposure to allergens and...

Great to have our paper out in @pnas.org showing that lung B cells in ectopic germinal centers undergo affinity maturation.

@smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...

03.04.2025 03:03 โ€” ๐Ÿ‘ 72    ๐Ÿ” 20    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 4
Preview
A natural experiment on the effect of herpes zoster vaccination on dementia - Nature Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...

I remember seejng this as a preprint a while ago, incredibly clever analysis, and profound inplications. So much biology to discover in the neuroimmune domain!! www.nature.com/articles/s41...

02.04.2025 18:26 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Call to arms by @lisamjarvis.bsky.social for biopharma to mobilize in support of the engines that power them - federally supported biomedical research and drug evaluation

01.04.2025 17:38 โ€” ๐Ÿ‘ 100    ๐Ÿ” 36    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
Preview
Irrational view of science under Trump not reflected beyond US, says EU research funder Prof Maria Leptin rejects view โ€˜this is a big opportunity to snatch back our colleaguesโ€™

โ€œInternet, vaccines, anything you can think of, were originally developed by publicly funded research programmes, and nobody at the time could have foreseen what would come out of them.โ€
@marialep.bsky.social

www.irishtimes.com/science/2025...

02.04.2025 14:48 โ€” ๐Ÿ‘ 10    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

"This is not a left or right moment. It is a right or wrong moment."

-- Senator Cory Booker, today

02.04.2025 03:51 โ€” ๐Ÿ‘ 12207    ๐Ÿ” 2030    ๐Ÿ’ฌ 124    ๐Ÿ“Œ 78

Thank you, Cory Booker for defending scientific research. Speaking out against the mindless, tragic loss of economic benefit, our global scientific competitive edge and hope for so many families in health crises so clearly after standing there for 24 hrs is remarkable.

01.04.2025 23:42 โ€” ๐Ÿ‘ 151    ๐Ÿ” 18    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

People/organizations with means and a vision for the future of biomedical science - we need an โ€œArc Instituteโ€ equivalent in the DMV area to sponge up all the incredible talent, opportunity of a lifetime for a visionary entrepreneur, I will help! @mcuban.bsky.social

01.04.2025 16:03 โ€” ๐Ÿ‘ 88    ๐Ÿ” 20    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
Preview
โ€˜One of the darkest daysโ€™: NIH purges agency leadership amid mass layoffs In shock move, four institute directors at the US biomedical agency are removed from their posts.

"This will go down as one of the darkest days in modern scientific history." Story on the decimation of NIH by @maxkozlov.bsky.social www.nature.com/articles/d41...?

01.04.2025 21:11 โ€” ๐Ÿ‘ 1587    ๐Ÿ” 661    ๐Ÿ’ฌ 42    ๐Ÿ“Œ 27

Go, @booker.senate.gov , Go!!! We need more like this from our leaders NOW.

01.04.2025 19:39 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Dillon Geyselaers (@dillongeyselaers) on Threads Your outie likes to drink alcohol and once sent top secret war plans to a journalist by mistake

Too good! www.threads.net/@dillongeyse...

25.03.2025 03:23 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

1. For the past thirty years I've had the best job in the world.

โ€จI've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.

19.03.2025 19:32 โ€” ๐Ÿ‘ 2615    ๐Ÿ” 943    ๐Ÿ’ฌ 39    ๐Ÿ“Œ 239
Preview
Opinion | DOGE Needs a Different Playbook for Science We need less administrative bloat in science.

โ€˜If a VC firm measured efficiency purely by how little money it spent, rather than by the returns it generated, it wouldnโ€™t last long. We invest in scientific research because we want returns โ€” in knowledge, in lifesaving drugs, in technological capability.โ€™

www.nytimes.com/2025/03/19/o...

19.03.2025 21:20 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Pls read and share with family members. Thank you AAI for speaking up!!

19.03.2025 14:06 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Opinion | We Were Badly Misled About Covid (Gift Article) The same dangerous mistakes. The same lack of candor.

Well worth a read. Not because of the content - it's total horseshit - but because it's a prime example of what happens when you mix anti-science, conspiracism, arrogance, and a total lack of expertise.

Maybe one day NYT OpEds will engage with the actual science ๐Ÿคทโ€โ™‚๏ธ.

www.nytimes.com/2025/03/16/o...

16.03.2025 16:32 โ€” ๐Ÿ‘ 594    ๐Ÿ” 156    ๐Ÿ’ฌ 28    ๐Ÿ“Œ 32
Post image

Cartoon by @paulnoth.bsky.social

12.03.2025 16:23 โ€” ๐Ÿ‘ 912    ๐Ÿ” 213    ๐Ÿ’ฌ 9    ๐Ÿ“Œ 10

Interested in germinal center regulation?
Should we coddle our immune system?
Two more weeks to apply!
3 year funding

13.03.2025 16:28 โ€” ๐Ÿ‘ 3    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Very excited our work out in @jem.org โ€œTransient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protectionโ€
@wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social
Thread below.

11.03.2025 03:26 โ€” ๐Ÿ‘ 54    ๐Ÿ” 21    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3

Congrats Joanna and team!!!

11.03.2025 04:56 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@tyewdell is following 20 prominent accounts