YouTube video by Bruce Springsteen Bruce Springsteen - Streets Of Minneapolis (Official Audio)

I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.

Stay free

Does a higher resistance exercise volume stimulate MPS more?

✅ 1 set vs 3 sets
✅ Early vs late MPS
✅ Within-subject design

Let’s break it down!

1/11

@mackinprof.bsky.social

Cover of Applied Physiology, Nutrition, and Metabolism journal showing a person tying shoelaces next to dumbbells indoors.

Our most read article of 2025 analyzes protein intake and all-cause, cardiovascular, and cancer-related mortality. Read it today ▶️ https://ow.ly/9hpX50XVvvF

👥: Yanni Papanikolaou, @mackinprof.bsky.social, Victor Fulgoni

#BestofCSP McMaster University

Cover of Applied Physiology, Nutrition, and Metabolism journal showing a person tying shoelaces next to dumbbells indoors.

APNM Journal🏋️🍎's most read article of 2025 analyzes protein intake and all-cause, cardiovascular, and cancer-related mortality. Read it today ▶️ https://ow.ly/Vrq050XVxB4

👥: Yanni Papanikolaou, @mackinprof.bsky.social, Victor Fulgoni

#BestofCSP McMaster University

What the actual f*ck is this... ??

Happy to do that

Would love if you got @mackinprof.bsky.social on the podcast to discuss some of the protein claims by @erictopol.bsky.social

One is made a national story every single week and the other is shhhhh.....

We can give ourselves so much more than the U.S. can ever take away. #CanadaStrong

Imagine if you lost so much muscle that your handgrip strength declined! Or your physical function worsened. Not right away, but perhaps a few years down the road. Could it be important?

It’s time to look out for ourselves and our workers, and stand up for Canada.

A crowd of people are gathered at a rally in support of Mark Carney in Kitchener-Waterloo, Ontario. 

President Trump’s tariffs will hurt, but they will not break us. 

We will get through this crisis together, because in Kitchener-Waterloo — and right across the country — we are #CanadaStrong.

The fact that the Department of Justice has not, and will never, launch an investigation into this massive national security breach tells you all you need to know about this lawless and profoundly corrupt Administration.

It was never about fentanyl...

Trump News and Live Updates: Zelensky Arrives for Meeting of European Leaders on Ukraine Britain’s prime minister announced the move ahead of a meeting with European leaders as the region reeled from President Trump’s confrontation with President Volodymyr Zelensky of Ukraine.

Prime Minister Keir Starmer of Britain said Sunday that he would work with the leaders of Ukraine and France on a cease-fire plan to end Russia’s war in Ukraine, as Europe reels from President Trump’s confrontation with President Volodymyr Zelensky of Ukraine.

If you worked for 18F and got fired, Group together to start a consulting company.

It’s just a matter of time before DOGE needs you to fix the mess they inevitably create.

They will have to hire your company as a contractor to fix it. But on your terms.

I’m happy to invest and/or help

Don’t let step reduction become muscle reduction.

📚 Recommended reading: The Impact of Step Reduction on Muscle Health in Aging: Protein and Exercise as Countermeasures

@saraoikawa @DrTHolloway @mackinprof

pubmed.ncbi.nlm.nih....

Physical Activity and Total Daily Energy Expenditure in... : Medicine & Science in Sports & Exercise older adults (50–74 yr) participating in the Interactive Diet and Activity Tracking in AARP study. TEE was assessed by doubly labeled water and PA by accelerometer. The relationship between PA and TEE...

Exercise does increase calorie burn – but probably not as much as you might hope theconversation.com/exercise-doe...

In line with the evidence journals.lww.com/acsm-msse/fu...

Really interesting work here

Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise Exercise regulates the human skeletal muscle interstitial fluid proteome in a distinct temporal manner.

Our latest! Great work from Ben Stocks and Atul Deshmukh!
Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise | Science Advances www.science.org/doi/10.1126/...

Hate to break it to y’all:

Trump increasing taxes on our biggest fruit & vegetable suppliers isn’t going to reduce cost of healthy foods or “make foods healthier”

But I guess influencers can scream that “big food” is evil while selling unregulated supplements…

The universe speaks in mysterious ways.

"Personhood" is Coming Your medical care and rights are at risk

Personhood is coming, it's only a matter of time open.substack.com/pub/vajenda/...

Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise - PubMed The skeletal muscle interstitial space is the extracellular region around myofibers and mediates cross-talk between resident cell types. We applied a proteomic workflow to characterize the human skele...

Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise pubmed.ncbi.nlm.nih.gov/39889004/

These data highlight the importance of cellular communication in the adaptive response to exercise.

Dear Canada and Mexico,

We’re so, so sorry.

— Sane America

I’m going to put my rich guy hat on and say I hope that Mexico and Canada issue equal, retaliatory tariffs and stick to them for an extended period.

I apologize to all the people it will cost money and the businesses it will hurt.

But it’s the only way for tariffs to be seen for what they are

The clockwork of champions: Influence of circadian biology on exercise performance Exercise physiology and circadian biology are distinct and long-standing fields. Recently they have seen increased integration, largely due to the dis…

“The clockwork of champions: Influence of circadian biology on exercise performance” by Stuart Hesketh and @kaesser.bsky.social.

www.sciencedirect.com/science/arti...

8/17

Exercise performance and health: Role of GLUT4 The glucose transporter GLUT4 is integral for optimal skeletal muscle performance during exercise, as well as for metabolic health. Physiological regu…

“Exercise performance and health: Role of GLUT4” by Sean McGee and Mark Hargreaves.

www.sciencedirect.com/science/arti...

7/17

Molecular aspects of the exercise response and training adaptation in skeletal muscle Skeletal muscle plasticity enables an enormous potential to adapt to various internal and external stimuli and perturbations. Most notably, changes in…

“Molecular aspects of the exercise response and training adaptation in skeletal muscle” by @regula-furrer.bsky.social and yours truly (@c-handschin.bsky.social).

www.sciencedirect.com/science/arti...

6/17

Exercise-specific adaptations in human skeletal muscle: Molecular mechanisms of making muscles fit and mighty The mechanisms leading to a predominantly hypertrophied phenotype versus a predominantly oxidative phenotype, the hallmarks of resistance training (RT…

“Exercise-specific adaptations in human skeletal muscle: Molecular mechanisms of making muscles fit and mighty” by @connorstead.bsky.social, @mackinprof.bsky.social and colleagues.

www.sciencedirect.com/science/arti...

5/17