Open Genes

Evidence for improved DNA repair in long-lived bowhead whale - Nature Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.  &nbs...

www.nature.com/articles/s41...

Open Genes — Biological database of human genes associated with aging Curated biological database of human genes associated with aging and longevity.

New article on our website: "Selection Criteria: How Open Genes Identifies Aging-Related Genes"

open-genes.com/about/articl...

Thanks to our contributors on GitHub:
trendspotter
Crabchicken

Special thanks to trenspotter for submitting the Czech translation and committing a fix. We will include all new fixes for our translations in the new release, along with the new workflow for fetching translations from Localazy

Release note image

New release!
open-genes.com
github.com/open-genes/o...

We’re just getting started. More changes are on the way

Nanostructures Trap Amyloid Beta, Rescuing Neurons Scientists have created engineered nanostructures that bind monomers and oligomers of harmful amyloid beta (Aβ) protein, preventing them from entering neurons and drastically […]

Study from Northwestern University: Scientists have engineered nanostructures that bind to harmful Alzheimer’s-related proteins like amyloid beta, preventing them from entering neurons and boosting cell survival in vitro.

Learn more: www.lifespan.io/news/nanostr...
By: @arkadimazin.bsky.social

Open Genes Open Genes is an open-source database of human genes associated with aging and longevity - Open Genes

We’ve started automating the process of mentioning contributors on our GitHub organization page. We’ve also included all contributors from both GitHub and GitLab. Turned out so many great people worked with us since the very start of the project! Thank you for your support!

github.com/open-genes

We are working on adding new languages ​​to our site, including Ukrainian, Czech, Spanish, Portuguese, German, Hindi and more

Hi Erik! Open Genes is a biological database of human genes associated with aging. We'd appreciate it if you added us to the feed.

Paper
doi.org/10.1093/nar/...

Official website
open-genes.com

Lead author
orcid.org/0000-0003-29...

www.researchgate.net/profile/Ekat...

What makes biological age epigenetic clocks tick - Nature Aging Nature Aging - What makes biological age epigenetic clocks tick

What makes biological age epigenetic clocks tick

Mahdi Moqri, Jesse R. Poganik, Steve Horvath, Vadim N. Gladyshev

www.nature.com/articles/s43...

EU medicines agency quits X, moves to Bluesky The European Medicines Agency (EMA) said on Monday it would no longer post on X and would use rival Bluesky instead, becoming the latest organisation to quit a social media platform that some have criticised for its content.

EU medicines agency quits X, moves to Bluesky

www.reuters.com/world/europe...

Open Genes—a new comprehensive database of human genes associated with aging and longevity Abstract. The Open Genes database was created to enhance and simplify the search for potential aging therapy targets. We collected data on 2402 genes assoc

Read our paper to learn more about how we focused on providing detailed data for each experiment, linking every single gene to human aging. academic.oup.com/nar/article/...

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Open Genes — Biological database of human genes associated with aging Curated biological database of human genes associated with aging and longevity.

Links:

Our website: open-genes.com
Our paper: academic.oup.com/nar/article/...
GitHub: github.com/const8ine
LinkedIn: www.linkedin.com/company/open...
Do you code? Use our public API: open-genes.com/api/docs

Open Genes—a new comprehensive database of human genes associated with aging and longevity Abstract. The Open Genes database was created to enhance and simplify the search for potential aging therapy targets. We collected data on 2402 genes assoc

Read more about confidence levels, and why we pay attention to maintaining them in the Open Genes database, in our paper: academic.oup.com/nar/article/...

Open Genes — Biological database of human genes associated with aging Curated biological database of human genes associated with aging and longevity.

Recently we added a dataset featuring genes and their confidence levels for download. open-genes.com/download
We divided genes into groups with different confidence levels based on the type of data supporting the link between the gene and aging. 1/2

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