AgingdocโญDavid Barzilai๐Ÿ””MD PhD, MS, MBA, DipABLM's Avatar

AgingdocโญDavid Barzilai๐Ÿ””MD PhD, MS, MBA, DipABLM

@agingdoc.bsky.social

Longevity medicine best practices | healthspan | precision medicine | geroscience | bio/acc | consulting @ agingdoc.com Connect: http://linkedin.com/in/agingdoc

2,943 Followers  |  5,581 Following  |  346 Posts  |  Joined: 05.11.2023  |  1.609

Latest posts by agingdoc.bsky.social on Bluesky

Preview
Boston's Longevity Obsession: What Works and What Doesn't We talked to doctors at Mass General, Brigham and Women's, and more.

Bostonโ€™s Longevity Obsession: What Works and Whatโ€™s Expensive BS

We're becoming more & more obsessed with living foreverโ€”but not all the treatments are created equal. What works, what doesnโ€™t and whether optimizing every aspect of your life is really worth it.
www.bostonmagazine.com/news/2026/01...

01.02.2026 21:20 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
How to Make Friends as an Adult

How to Make Friends as an Adult

A practical guide for expanding your circle, with advice from sociable people.

www.nytimes.com/article/how-... @nytstyle.bsky.social

01.02.2026 19:27 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Glucagon-like peptide-1 medicines and cancer - Nature Cancer Yabut and Drucker discuss clinical and preclinical evidence about the potential roles of GLP-1 medicines on cancer incidence, development and therapy and speculate about their mechanism on cancer cell...

Glucagon-like peptide-1 medicines and cancer

www.nature.com/articles/s43...

23.01.2026 12:17 โ€” ๐Ÿ‘ 6    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Senate advances bills rejecting Trumpโ€™s efforts to slash research funding The White House sought cuts of 40% or more at some agencies, but lawmakers from both parties are pushing to hold science spending relatively steady.

Senate advances bills rejecting Trumpโ€™s efforts to slash research funding ๐Ÿงช

The White House requested cuts of 40% or more at some agencies. But lawmakers from both parties are pushing to hold science spending relatively steady.

www.highereddive.com/news/senate-...

20.01.2026 22:40 โ€” ๐Ÿ‘ 11    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Irradiatedย cannabisย might still harbour toxic fungi and residues, McGill study finds Gamma irradiation, an industry-standard sterilization method for medicinal and recreational cannabis, does not fully eliminate toxic fungi or their chemical residues, a McGill University study has fou...

Irradiated cannabis might still harbour toxic fungi and residues, McGill study finds

Researchers raise concerns about possible health risks for vulnerable users, point to a need for better methods and safeguards

www.mcgill.ca/newsroom/cha...

15.01.2026 19:39 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Targeted delivery of genome editors in vivo

๐Ÿงฌ"Targeted delivery promises to considerably expand the therapeutic applicability of genome editing, moving closer to the ideal of a precise โ€˜magic bulletโ€™ that safely and effectively treats diverse genetic disorders." ๐Ÿฉบ

www.nature.com/articles/s41...

13.01.2026 15:18 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ‘โš•๏ธ

13.01.2026 15:16 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

My friend Andrew Steele is building this:

The majority of poor health and deaths globally are caused by diseases that become common with age...

"But public policy has yet to catch up.. & longevity science is underappreciated, and underfunded

We exist to change that" ๐Ÿง‘โ€โš•๏ธโš•๏ธ

thelongevityinitiative.org

28.12.2025 18:07 โ€” ๐Ÿ‘ 9    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Post image

This company is developing gene therapies for muscle growth, erectile dysfunction, and โ€œradical longevityโ€

๐Ÿ’‰ A small group of volunteers will receive multiple injections of the experimental treatments next month, says Unlimited Bio ๐Ÿ‘จ๐Ÿปโ€โš•๏ธ

t.co/hMdyfVk58W

23.12.2025 02:20 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Post image

Interrupting Prolonged Sitting Reduces Postprandial Glucose Concentration in Young Men With Central Obesity

๐Ÿ‘‰ Interrupted prolonged sitting [3 min light walking or 1.5 minutes of moderate walking every 30 minutes] reduced postprandial glucose concentrations.

academic.oup.com/jcem/article...

06.12.2025 15:22 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

People often ask me the same question:

โ€œWhatโ€™s the single most promising anti-aging measure coming in the next decade?โ€

If you care about where longevity medicine is truly heading, this oneโ€™s worth a look.

๐Ÿ”—https://www.instagram.com/reel/DRni2qQgNTS

28.11.2025 23:20 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Agingdoc๐ŸฉบDr David Barzilai๐Ÿ””MD PhD MS MBA DipABLM on X: "Semaglutide versus caloric restriction-induced weight loss: insights into effects on skeletal muscle mass and function "...suggests that the loss of muscle function and mass during treatment is not unique to GLP-1RA pharmacology but rather reflects the biology of caloric" / X Semaglutide versus caloric restriction-induced weight loss: insights into effects on skeletal muscle mass and function "...suggests that the loss of muscle function and mass during treatment is not unique to GLP-1RA pharmacology but rather reflects the biology of caloric

Semaglutide versus caloric restriction-induced weight loss: insights into effects on skeletal muscle mass and function

"[suggests] loss of muscle function and mass during treatment is not unique to GLP-1RA pharmacology but rather reflects the biology of caloric restrictionโ€ฆ"

x.com/agingdoc1/st...

19.11.2025 00:41 โ€” ๐Ÿ‘ 8    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

My post from Founders Forum North America (NYC) ๐Ÿ—ฝ

๐Ÿ”— www.linkedin.com/posts/agingd... ๐Ÿš€

09.11.2025 22:48 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
AI Learns to Design the Human Bodyโ€™s Most Elusive Proteins - Neuroscience News A new machine learning method has achieved what even AlphaFold cannot โ€” the design of intrinsically disordered proteins (IDPs), the shape-shifting biomolecules that make up nearly 30% of all human pro...

AI Learns to Design the Human Bodyโ€™s Most Elusive Proteins

๐Ÿคฉ Summary: A new machine learning method has achieved what even AlphaFold cannotโ€ฆ their ever-changing structures have defied traditional AI prediction models.

neurosciencenews.com/ai-protein-d...

07.10.2025 00:07 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Human skin DNA fertilised to make embryo for first time US scientists testing the technique say it could help people overcome infertility and potentially allow same-sex couples to have a genetically related child.

Scientists make embryos from human skin DNA for first time

www.bbc.com/news/article...

30.09.2025 20:05 โ€” ๐Ÿ‘ 9    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

This AI tool predicts your risk of 1,000 diseases โ€” by looking at your medical records

Trained on 400,000 medical records, the system can predict risks 20 years in advance โ€” plus, how AIs could make you more likely to cheat

nature.com/articles/d41...

@shamini.bsky.social ๐Ÿงช

30.09.2025 11:28 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Sex-specific longitudinal reversal of aging in old frail mice | Aging Aging | doi:10.18632/aging.206304. Cameron Kato, Jessica Zheng, Cindy Quang, Sophia Siopack, Joana Cruz, Zachery R. Robinson, Nicole Fong, Zhixin A. Zhang, Patrick Young, Michael J. Conboy, Irina M. C...

Sex-specific longitudinal reversal of aging in old frail mice

www.aging-us.com/article/2063...

28.08.2025 23:07 โ€” ๐Ÿ‘ 8    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
The evolution of cancer and ageing: a history of constraint - Nature Reviews Cancer In this Perspective, de Magalhรฃes explores the evolutionary relationship between cancer and ageing, proposing that the need to minimize cancer risk early in life may contribute to tissue degeneration ...

The evolution of cancer and ageing: a history of constraint

www.nature.com/articles/s41...

28.08.2025 23:02 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@erictopol.bsky.social is right โ€” we havenโ€™t rigorously validated gerotherapeutics in humans, and even if we did, weโ€™d need to show they also compress morbidity.

Some source for optimism: for some animal models, better healthspan can track increased longevity.

pmc.ncbi.nlm.nih.gov/articles/PMC...

28.08.2025 22:45 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Weโ€™re thrilled to welcome David Barzilai MD PhD MBA MS DipABLMโ€”an internationally acclaimed expert in longevity, CEO of Healthspan Coaching LLC, and a founding faculty member and Trustee of theโ€ฆ | Rev... Weโ€™re thrilled to welcome David Barzilai MD PhD MBA MS DipABLMโ€”an internationally acclaimed expert in longevity, CEO of Healthspan Coaching LLC, and a founding faculty member and Trustee of the Geneva...

www.linkedin.com/feed/update/...

07.08.2025 19:01 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Fraudulent Scientific Papers Are Rapidly Increasing, Study Finds

Fraudulent Scientific Papers Are Rapidly Increasing, Study Finds

A statistical analysis found that the number of fake journal articles being churned out by โ€œpaper millsโ€ is doubling every year and a half. ๐Ÿคฏ

www.nytimes.com/2025/08/04/s...

05.08.2025 13:21 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

See you there!

02.08.2025 16:05 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ‘

Youโ€™re not on X anymore right (making sure I didnโ€™t miss you there for cross-posting)?

Keep up the great work Laura!

02.08.2025 11:02 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Healthy Lifestyle Can Help People at Risk for Dementia, Study Finds

Healthy Lifestyle Can Help People at Risk for Dementia, Study Finds

The study found that a combination of exercise, healthy diet and other behaviors led to cognitive benefitsโ€ฆ

www.nytimes.com/2025/07/28/h...

02.08.2025 10:59 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

DNA Methylation Ageing Atlas Across 17 Human Tissues

๐Ÿ‘‰โ€œOur open-access atlas provides a foundational resource for dissecting the molecular architecture of human aging and identifying testable targets for intervention..โ€

@nireynon.bsky.social and coauthors

www.biorxiv.org/content/10.1...

28.07.2025 21:01 โ€” ๐Ÿ‘ 5    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Frontiers | Editorial: Resilience in aging In this editorial, we discuss contributions to the research topic of Resilience in Aging. Resilience refers to the capacity to recover from stress and restor...

Editorial: Resilience in aging

@drlaurahaynes.bsky.social and coauthors

www.frontiersin.org/journals/agi...

28.07.2025 20:52 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
Post image

AlphaGo Moment for Model Architecture Discovery

๐Ÿ‘‰โ€œASI-Arch is presented, the first demonstration of Artificial Superintelligence for AI research (ASI4AI) in the critical domain of neural architecture discovery, with the first empirical scaling law for scientific discovery itself..โ€œ

t.co/ljJ1fXsslE

28.07.2025 17:06 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Preview
Fearful of AI-generated grant proposals, NIH limits scientists to six applications per year Some critics of the new policy say the cap could hinder researchers in need of funding

Fearful of AI-generated grant proposals, NIH limits scientists to six applications per year

Some critics of the new policy say the cap could hinder researchers in need of funding

www.science.org/content/arti...

21.07.2025 16:43 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
'They hold hands, they embrace, they kiss': The woman who changed our view of chimps - and human beings In 1960, Jane Goodall began her groundbreaking field study by living among chimpanzees in Tanzania. In 1986, she told the BBC how similar chimps and humans really are.

'They hold hands, they embrace, they kiss': The woman who changed our view of chimps - and human beings

www.bbc.com/culture/arti...

15.07.2025 18:55 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Just How Harmful Is Vaping? More Evidence Is Emerging.

Just How Harmful Is Vaping? More Evidence Is Emerging.

A new study that found high levels of heavy metals in popular nicotine vapes adds to concerns about the products.

www.nytimes.com/2025/07/09/w...

09.07.2025 14:08 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@agingdoc is following 20 prominent accounts