Masschelein Lab

Directing Biosynthesis VIII - submit your oral abstract by 2 February 2026

Oral abstract submission is now open for Directing Biosynthesis VIII, an event that has been connecting #Biosynthesis researchers for over a decade.

Network and discuss the latest research, get all the details and submit: rsc.li/dbviii

#DBVIII #ChemSky

17.11.2025 15:51 — 👍 2    🔁 3    💬 0    📌 1

Bluesky

... Dries De Ruysscher,
@hansgerstmans.bsky.social, Giel Vanreppelen, Laura-Lynn Huybrechts

27.10.2025 10:05 — 👍 0    🔁 0    💬 0    📌 0

Huge congratulations to Fatima El Arnouki Belhaji for her brilliant work on this, and thanks to everyone who helped
@marnixmedema.bsky.social, Mohammad Alanjary, @mmzdouc.bsky.social, Eveline Lescrinier, Angus Weir,
@scyphs.bsky.social, @patrickvandijk.bsky.social ...

27.10.2025 10:04 — 👍 2    🔁 0    💬 2    📌 0

Through genome mining and comparative bioinformatics and metabolomics, we illuminate how these triple hybrid systems expand Nature’s biosynthetic creativity. We also discovered the chitinimines, a new family of specialized lipid-containing natural products metabolites from Chitinimonas koreensis.

27.10.2025 09:57 — 👍 3    🔁 0    💬 1    📌 0

Charting the biosynthetic landscape of hybrid polyketide-nonribosomal peptide-specialized lipids Polyunsaturated fatty acid (PUFA) synthase-like enzymes are best known for their role in membrane lipid biosynthesis in marine bacteria, but have also been repurposed for the assembly of specialized l...

Polyunsaturated fatty acid (PUFA) synthase enzymes turn out to be far more versatile than we ever imagined! In our new preprint, we reveal a largely untapped biosynthetic space where they team up with PKSs and NRPSs to create new types of bioactive amphiphilic metabolites.
👉http://bit.ly/4hzUUak

27.10.2025 09:56 — 👍 8    🔁 3    💬 1    📌 2

Last chance to join the #Microbes25 party. Join us to explore how microbial cell factories, synthetic biology, and microbial engineering are rewriting the rulebook of applied #microbiology. Final registration is 23 Oct, grab your spot before it's gone:https://vibbio.tech/3KyHcIb
#VIBConf

07.10.2025 13:05 — 👍 3    🔁 2    💬 1    📌 0

CAGEcleaner: reducing genomic redundancy in gene cluster mining AbstractMotivation. Mining homologous biosynthetic gene clusters (BGCs) typically involves searching colocalised genes against large genomic databases. How

🚨 Tired of redundant #BiosyntheticGeneCluster hits?

💥 Check out #CAGEcleaner – our new genome-level dereplication pipeline for BGC mining and comparative analysis. Works with cblaster & CAGECAT.

Now out in Bioinformatics: bit.ly/3TghJEx
🔗 GitHub: bit.ly/44rNZK9
🙌 Kudos to our PhD student Lucas!

27.06.2025 14:26 — 👍 4    🔁 0    💬 0    📌 0

🥳 Huge congratulations to Prof. Joleen Masschelein (@masscheleinlab.bsky.social, @viblifesciences.bsky.social, @kuleuvenuniversity.bsky.social) for being awarded the 2025 EFMC Academia Prize!

09.05.2025 12:44 — 👍 6    🔁 1    💬 1    📌 0

The new #antiSMASH v8 paper is out in @narjournal.bsky.social! It was a pleasure helping to improve the detection of bacterial polyyne biosynthetic gene clusters. Happy mining! 🧬🔍

28.04.2025 22:10 — 👍 6    🔁 0    💬 0    📌 0

We are so happy to share that the 2nd Emerging Microbial Technologies conference will take place in Gent next 25th April 2025!!

This edition is jointly organized by CMET_UGENT and YBSMicrobiology
Follow us also on LinkedIn and X @EMT_conference

05.12.2024 11:39 — 👍 2    🔁 2    💬 1    📌 0

Thanks for the warm welcome!

15.01.2025 23:53 — 👍 1    🔁 0    💬 0    📌 0

🎄✨ Festive vibes at our annual lab Christmas dinner! Great food and lots of laughter to wrap up a wonderful year of science and teamwork. Here's to more discoveries and collaborations in the year ahead! 🧫🔬

14.12.2024 15:46 — 👍 6    🔁 0    💬 1    📌 0

Two weeks ago, we had the pleasure to welcome @nadineziemert.bsky.social as a guest speaker at our Microbes & Booze seminar. She gave a very inspiring talk on mining genomes for new antibiotics - thanks for your visit! 💊🍻

19.11.2024 11:58 — 👍 15    🔁 3    💬 1    📌 0