Tuuli Lappalainen's Avatar

Tuuli Lappalainen

@tuuliel.bsky.social

Professor at KTH, NY Genome Center, SciLifeLab, working on functional genomics and human genetics.

6,918 Followers  |  896 Following  |  382 Posts  |  Joined: 11.09.2023
Posts Following

Posts by Tuuli Lappalainen (@tuuliel.bsky.social)

Made a short video as a response. 3 questions remain for me.

1) What is the definition of a "DEl activity," and how is it being communicated to NIH staff so they can determine whether a grant qualifies?

(Continued below)

01.03.2026 22:24 β€” πŸ‘ 57    πŸ” 29    πŸ’¬ 3    πŸ“Œ 5

In my utopian vision of the future, instead of offloading all the pointless, annoying work tasks (like reports that none one will read and needlessly opaque forms) to robots, we restructure work and society so that the pointless tasks don't happen at all.

27.02.2026 23:28 β€” πŸ‘ 2383    πŸ” 377    πŸ’¬ 6    πŸ“Œ 35
Preview
White House stalls release of approved US science budgets The US Congress rejected sweeping cuts to science agencies. But the NIH, the NSF and NASA have had their spending slowed.

Congress rejected massive cuts to US science budgets for 2026, but much of the money still isn’t flowing to researchers.

The culprit? The White House Office of Management and Budget (OMB) is quietly slow-walking the release of funds. πŸ§΅πŸ‘‡

27.02.2026 16:06 β€” πŸ‘ 987    πŸ” 665    πŸ’¬ 20    πŸ“Œ 67
Bioinformatician/Staff Scientist in Medical Genomics Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...

I have an opening for a staff scientist or bioinformatician in my group at the Sanger Institute (closing date 24 March). Our current projects focus on disentangling rare and common variant contributions to rare neurodevelopmental conditions and to neurodevelopmental and perinatal traits. 1/2

25.02.2026 20:56 β€” πŸ‘ 14    πŸ” 13    πŸ’¬ 1    πŸ“Œ 0

I understand why chatbot cheating happens but every time I read about it I want to gently remind everyone that the point of schoolwork is not for the submission to exist. Teachers are not just greedy for more essays or solved equations. The point is to do the work WITH YOUR OWN BRAIN, FOR LEARNING.

24.02.2026 19:37 β€” πŸ‘ 3708    πŸ” 862    πŸ’¬ 100    πŸ“Œ 49

Minua alkaa oikeasti pelottaa, ettΓ€ suomalainen eliitti ja media ei tajua sitΓ€, kuinka todella pihalla valtavirtainen makrotaloustiede on taloudellisesta todellisuudesta. Yli 10 prosentin tyΓΆttΓΆmyydessΓ€ siunataan jopa 15 mrd. euron sopeutusta tuleville vuosille odottaen suhdanteen korjaavan.
#tiede

24.02.2026 11:55 β€” πŸ‘ 267    πŸ” 50    πŸ’¬ 7    πŸ“Œ 4
Post image

The culmination of a lot of excellent work, @marlmatos.bsky.social defending her PhD thesis today. Co-mentored by @tuuliel.bsky.social, exceptional insights into molecular quantitative trait loci in CD4+ T cells

@einsteinmededu.bsky.social

17.02.2026 18:21 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 2
Post image

pretty stunning chart

15.02.2026 19:58 β€” πŸ‘ 3165    πŸ” 1154    πŸ’¬ 230    πŸ“Œ 525

The political lesson of the last 20 years is that when putatively left-of-center parties promise voters hope and change, but then deliver more of the same, it ends up creating the backlash conditions for right-wing authoritarianism.

It’s a very straightforward truism.

15.02.2026 22:39 β€” πŸ‘ 141    πŸ” 31    πŸ’¬ 8    πŸ“Œ 1

Upeeta kun ensin talouskurin opeilla leikataan Suomesta kaikki kasvun edellytykset ja sitten kun kasvua ei kuulu niin siihen tarjotaan lÀÀkkeeksi samaa talouskuria.
Onko suomalaiset oikeesti nÀin tyhmiÀ, vai pelkÀstÀÀn Hesarin pÀÀkirjoitustoimitus?

13.02.2026 12:42 β€” πŸ‘ 206    πŸ” 42    πŸ’¬ 9    πŸ“Œ 1
Post image

Happy birthday to one of my favourite haters, Charles Darwin

12.02.2026 16:31 β€” πŸ‘ 10351    πŸ” 3081    πŸ’¬ 162    πŸ“Œ 419

This is super cool science, empowered by our infrastructure team at @scilifelab-ngi.bsky.social @scilifelab.se !

12.02.2026 18:40 β€” πŸ‘ 12    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

AI bot writes emo blog about not getting to play coder on GitHub… we are literally re-creating simulacrum of the most cringe ppl on the internet…

12.02.2026 17:17 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Congratulations!!

11.02.2026 22:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ–₯οΈπŸ§¬πŸš€ I am excited to share that our #omnideconv study is finally published on Genome Biology: doi.org/10.1186/s130...

11.02.2026 17:22 β€” πŸ‘ 20    πŸ” 11    πŸ’¬ 1    πŸ“Œ 0
⚑️ NEW: Jeffrey Epstein Recruited NSA Codebreakers for Genome β€œManhattan Project”

The financier pursued cryptographers to β€œhack” the genetic code, and develop β€œnew signals intelligence” to understand inter-cellular communication.

Story for Drop Site by 
@ryangrim
, 
@MazMHussain
, and 
@emilyjashinsky
https://www.dropsitenews.com/p/jeffrey-epstein-recruited-nsa-codebreakers-genome-russia-skolkovo-bill-gates-mit

⚑️ NEW: Jeffrey Epstein Recruited NSA Codebreakers for Genome β€œManhattan Project” The financier pursued cryptographers to β€œhack” the genetic code, and develop β€œnew signals intelligence” to understand inter-cellular communication. Story for Drop Site by @ryangrim , @MazMHussain , and @emilyjashinsky https://www.dropsitenews.com/p/jeffrey-epstein-recruited-nsa-codebreakers-genome-russia-skolkovo-bill-gates-mit

⚑️ NEW: Jeffrey Epstein Recruited NSA Codebreakers for Genome β€œManhattan Project”

The financier pursued cryptographers to β€œhack” the genetic code, & develop β€œnew signals...

Story for Drop Site by @ryangrim.bsky.social, @mazmhussain.bsky.social & Emily Jashinsky

www.dropsitenews.com/p/jeffrey-ep...

11.02.2026 14:16 β€” πŸ‘ 33    πŸ” 8    πŸ’¬ 3    πŸ“Œ 3
Video thumbnail

Yesterday the UK Government published a data provision notice paving the way for coded GP data in England to be shared with consented cohorts like UK Biobank.

Hear from Val, a UK Biobank participant on her hopes for the future.

11.02.2026 12:20 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0
Preview
The Biology of Genomes Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

Reminder that the abstract deadline for the Biology of Genomes meeting at CSHL is on Feb 13! We have a fantastic lineup of keynote speakers (Janet Kelso and Jonathan Pritchard) and session chairs. Submit your best science to this exciting and engaged meeting!
meetings.cshl.edu/meetings.asp...

05.02.2026 14:24 β€” πŸ‘ 19    πŸ” 11    πŸ’¬ 0    πŸ“Œ 2
Post image

🧬 New preprint alert! After years of collaborative work across 52 datasets we are presenting eQTLGen phase 2: a genome-wide eQTL meta-analysis covering 43,301 blood samples: www.medrxiv.org/content/10.6... (1/8)

06.02.2026 10:14 β€” πŸ‘ 36    πŸ” 21    πŸ’¬ 1    πŸ“Œ 4

We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT

15.10.2025 15:53 β€” πŸ‘ 162    πŸ” 211    πŸ’¬ 1    πŸ“Œ 5

The lesson for all the students out there is that science is a community project. Most of us make individually small contributions to this project. Success is measured at the collective level. Many of our professional (and personal) dysfunctions could be fixed by more fully embracing this view.

07.02.2026 11:20 β€” πŸ‘ 75    πŸ” 20    πŸ’¬ 1    πŸ“Œ 2
Albert Einstein College of Medicine hiring Postdoctoral position studying functional non-coding variants in neurodevelopmental disorders, Bronx, New York City, USA c in New York City Metropolitan Area... Posted 9:40:20 PM. A postdoctoral fellow position is open with 2 years of funding from the Simons Foundation Autism…See this and similar jobs on LinkedIn.

Please share this with your network: Postdoctoral position available in my group.

www.linkedin.com/jobs/view/43...

05.02.2026 22:47 β€” πŸ‘ 4    πŸ” 12    πŸ’¬ 1    πŸ“Œ 1
Albert Einstein College of Medicine | Medical Education | Biomedical Research

Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine.

faculty-einstein.icims.com/jobs/17847/a...

05.02.2026 22:14 β€” πŸ‘ 27    πŸ” 47    πŸ’¬ 1    πŸ“Œ 1

I think it's best for everyone to understand that the unified class project of billionaires right now is to do to white collar workers what globalization and neoliberalism did to blue collar workers.

04.02.2026 19:41 β€” πŸ‘ 12951    πŸ” 3436    πŸ’¬ 235    πŸ“Œ 241

I started offering career advice to two junior colleagues today in separate meetings, and both times I caught myself thinking that, if I'm honest, I don't have very good advice on navigating the current funding and job climate. I think it's important to say that no one does.

03.02.2026 03:46 β€” πŸ‘ 169    πŸ” 29    πŸ’¬ 5    πŸ“Œ 3

Kohta paljastuu kaikille, ettΓ€ hyvinvointivaltio tukikin rakenteellisesti taloutta ja talouskasvua, jolloin sen romuttaminen oli onneton rakenteellinen uudistus negatiivisin pitkΓ€n aikavΓ€lin vaikutuksin. Kiitos!

#talous #politiikka #yhteiskunta

03.02.2026 06:20 β€” πŸ‘ 267    πŸ” 55    πŸ’¬ 11    πŸ“Œ 4

Nature and Science journalists denied entry to event featuring NIH Director

31.01.2026 02:50 β€” πŸ‘ 349    πŸ” 154    πŸ’¬ 5    πŸ“Œ 2

Does the noncoding genome actually carry more genetic information than coding seqs? Motivated by this question we mutated every bp in the 10kb MYC locus. Results are even more exciting: Decoding the MYC locus reveals a druggable ultraconserved RNA element www.biorxiv.org/content/10.6...

31.01.2026 01:13 β€” πŸ‘ 128    πŸ” 47    πŸ’¬ 4    πŸ“Œ 6
Frequently Asked Questions (FAQs) | Grants & Funding

Because of technical issues with the SciENcv website, NIH is extending a period of leniency accepting old format biosketches through May 2026 (see FAQ #5):

grants.nih.gov/faqs#/common...

29.01.2026 20:30 β€” πŸ‘ 21    πŸ” 18    πŸ’¬ 6    πŸ“Œ 0
Post image

RFKJr's principal accomplishment as the nation's health guardian.

28.01.2026 16:08 β€” πŸ‘ 61    πŸ” 34    πŸ’¬ 2    πŸ“Œ 1