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Ben Raphael

@braphael.bsky.social

Graduate Class of 1991 Professor of Computer Science, Princeton University

1,014 Followers  |  46 Following  |  2 Posts  |  Joined: 26.09.2023  |  1.5328

Latest posts by braphael.bsky.social on Bluesky

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A graph homomorphism approach for unraveling histories of metastatic cancers and viral outbreaks under evolutionary constraints - Nature Communications Human diseases may evolve by migration or spread, but understanding these complex processes is challenging. Here, the authors leverage graph homomorphisms to reconstruct trees describing histories of ...

Check out this new publication by IICD member @braphael.bsky.social and team in @natcomms.nature.com: Graph Homomorphism Approach for Unraveling Histories of Metastatic Cancers and Viral Outbreaks under Evolutionary Constraints

www.nature.com/articles/s41...

08.09.2025 13:59 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Categorization of 34 computational methods to detect spatially variable genes from spatially resolved transcriptomics data - Nature Communications In spatial transcriptomics data analysis, identifying spatially variable genes (SVGs) is crucial for understanding tissue organization and function. The authors categorize 34 computational methods for...

How do we detect spatially variable genes (SVGs) in spatial transcriptomics?

In our Nature Communications review, we categorize 34 computational methods into three categories:
โœ… Overall SVGs
โœ… Cell-type-specific SVGs
โœ… Spatial-domain-marker SVGs

www.nature.com/articles/s41...

05.02.2025 19:50 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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NIH ban on renewing senior scientists adds to assaults on its in-house research Policy follows firings of tenure-track scientists and suspension of training programs

Friends, I am at a loss of words for how devastating it would be to lose the entire intramural #NIH program. Some of the biggest medical and scientific breakthroughs have come from scientists in the NIH Intramural program. #SaveTheNIH ๐Ÿงฌ๐Ÿงช ๐Ÿ–ฅ๏ธ ๐Ÿง 

www.science.org/content/arti...

27.02.2025 12:04 โ€” ๐Ÿ‘ 1103    ๐Ÿ” 334    ๐Ÿ’ฌ 30    ๐Ÿ“Œ 9

RECOMB-CCB workshop is combing to Seoul, chaired by @shenhui1986.bsky.social and Andrew Roth! Submissions are open for papers and abstracts

22.01.2025 15:16 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Impressions from Ascona Workshop: Spatial and temporal statistical modeling in molecular biology

www.huber.embl.de/group/events...

09.09.2024 15:30 โ€” ๐Ÿ‘ 11    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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A latent variable model for evaluating mutual exclusivity and co-occurrence between driver mutations in cancer bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Yes, the preprint is here: www.biorxiv.org/content/10.1...

12.08.2024 18:36 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
RECOMB-CCB: Computational Cancer Biology

Now: Keynote by Peter Park: A new mechanism for oncogene amplification. #RECOMB2024 ๐Ÿ’ป๐Ÿงฌ๐Ÿงช

27.04.2024 17:34 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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