Paris-Saclay Institute of Neuroscience

A Post-Doc position is open in the @touchmovelab.bsky.social of the institute. Learn more and apply 🔽🔽🔽

Convergent information flows explain recurring firing patterns in cerebral cortex - Nature Neuroscience Reproducible cortical firing patterns arise from hierarchical modular networks shaped by distance-dependent connectivity rather than attractor dynamics, suggesting that cortex is prewired for scaffold...

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How do reproducible brain activity patterns really emerge? Analyzing the MICrONS dataset, Alain Destexhe and collaborators @domguarino.bsky.social and @janantolik.bsky.social propose a new view based on a hierachy of neurons.

▶️ Learn more in @natcomms.nature.com 🔽🔽🔽

👩‍🎓 Upcoming thesis defense !

▶️ Cinthia Hernandez Puente will soon defend her PhD on the Redox control of stemness in the Xenopus retina 🐸👁️🧠, supervised by Morgane Locker, in the team of @murielperron.bsky.social.

📅 Join her at NeuroPSI on December the 16th at 1:30pm !

A large-scale study across the avian clade identifies ecological drivers of neophobia Neophobia (the aversive response to novelty) varies considerably across species and individuals, and can impact adaptability and survival. This study assesses neophobia in 1400 subjects from 136 bird ...

😱🕊️ Isabelle George @neuropsi.bsky.social is part of consortium @themanybirds.bsky.social (89 institutions!) that showed that the diversity in fear-of-novelty response across bird 🦢 🦜 species 🦉 🦆 🦃 is driven by their diet and migratory behavior!

▶️ Read their latest @plosbiology.org article:

📅 Mark the date !

▶️We will soon host Maria Antonietta Tosches (Assistant Professor, Columbia University, New-York).

▶️ She will present her work on the Evolution of cell types and circuits in the vertebrate brain in the NeuroPSI seminar, on Friday 05 Dec 2025 at 11h30.

👩‍🎓 Sambre Mach will defend her PhD entitled "Local control of cerebellar noradrenaline and dopamine release by Bergmann glia and Purkinje cells", directed by Glenn Dallérac and Micaela Galante.

📅 You are welcome Tuesday, the 2nd of December 2025. Salle Albe-Fessard, NeuroPSI!

🤩 We are pleased to welcome Glenda Comai as a new group leader in the institute.

▶️ Glenda is a specialist of the neuro-muscular system, its development, regeneration and evolution. Learn more about our new PI: neuropsi.cnrs.fr/en/glenda-co...

🧑‍🎓 Le 10/12/2025, Marie Absalon soutiendra en Français sa thèse "Apprendre à apprendre grâce à l’intelligence artificielle", co-dirigée par Thomas Deneux, Ingénieur de Recherche @neuropsi.bsky.social.

▶️ Rendez-vous à 9h30 au Learning Planet Institute, 8 bis rue Charles V, 75004 Paris !

▶️ The next NeuroPSI Seminar (Friday 28 Nov 2025) is invited by Glenn Dallérac.

▶️ Austen Milnerwood @mcgill.ca, Canada, will talk about the the pathophysiology of knock-in mouse models of Parkinson’s disease & comparisons with patient-derived neurons.

🐟 Note that at the same time (!), Hannah Wiggett will defend her PhD directed by Jean-Pierre Levraud, on the Diverse Cellular Responses and Neurological Outcomes of Interferon Signalling in the Zebrafish.

📅 When/Where: The 27th of November at 14:00 (CET), at the @pasteur.fr main campus.

🎓 Den Whilrex Garcia will defend his PhD, carried under the direction of Sabir Jacquir, on the modeling of interactions between neurons and astrocyte: Application to brain information processing.

📅 When: Thursday the 27th of November, at 1:30pm.
🗺️ Where: NeuroPSI

▶️ Please attend!

🔬 🙋‍♀️ Pour soutenir notre plateforme d'imagerie, NeuroPSI bénéficie d’une Fonction Susceptible d’Être Pourvue (FSEP) au sein du CNRS, pour recruter une/un Ingénieur(e) en instrumentation biologique via une mobilité interne.

➡️ Vous êtes agents du CNRS, intéressés par cette mobilité ? Contactez-nous !

Sharp waves, bursts, and coherence: Activity in a songbird vocal circuit is influenced by behavioral state Similar to motor skill learning in mammals, vocal learning in songbirds requires a set of interconnected brain areas that make up an analogous basal ganglia-thalamocortical circuit known as the anteri...

🐦 🗣️😴 What is the impact of behavioral state on the songbird vocal circuit?

Nicolas Giret @neuropsi.bsky.social & collaborators @ethz.ch, @neurobordeaux.bsky.social & @tumunich.bsky.social show the impact of sleep on this fascinating motor circuit, in an @sfnjournals.bsky.social publication 🔽🔽🔽

L’apprentissage sensorimoteur se matérialise par une conversation entre plusieurs régions du cerveau, à savoir le cortex, les ganglions de la base et le thalamus. Reste à comprendre comment ces zones dialoguent. C’est tout l’objet du projet SleepinBrainDyn, dirigé par Nicolas Giret, chercheur CNRS à l’Institut des neurosciences Paris-Saclay (NeuroPSI - CNRS/Université Paris-Saclay). Crédit : © Nicolas Giret/NeuroPSI

🐦🎶Quand l’oiseau se tait, son cerveau continue de chanter. Le projet SleepinBrainDyn, financé par l'ANR et dirigé au @neuropsi.bsky.social à Saclay, révèle comment les neurones rejouent la leçon pendant le repos. Un éclairage inédit sur l’apprentissage moteur.

▶ lejournal.cnrs.fr/nos-blogs/fo...

The what, which, when, why and who of Off responses in the auditory system Abstract figure legend In this article, we will first review ‘What’ different mechanisms are involved in the generation of Off responses at the sub-cortical and cortical level of the auditory system....

⁉️❔❓ The what, which, when, why and who of OFF responses in the auditory system ⁉️❔❓

Read this review of negative representations of sound across the auditory system in @jphysiol.bsky.social, by Jean-Marc Edeline @neuropsi.bsky.social and Robert Liu @emoryuniversity.bsky.social 🔽🔽🔽

Spatio-temporal dynamics of ingroup interactions in macaques - Scientific Reports Scientific Reports - Spatio-temporal dynamics of ingroup interactions in macaques

🐒🐒🐒 Who sits next to whom? Who keeps their distance? It turns out that macaques space use reflects social bonds, hierarchy, and hidden group structures.

🐒🐒🐒 Learn more in the study by Tadeusz Kononowicz @neuropsi.bsky.social and collaborators at @isc-mj.bsky.social in Science Advances 🔽🔽🔽

Yes, this is the paper, thank you!

🤯 👁️ Did you know the primary visual cortex tracks head movements even in complete darkness?

Guy Bouvier and colleagues managed to decode multiple head movement variables in V1 without light in the room, and discovered two distinct brain sources delivering these signals!

Read more in PNAS 🔽🔽

▶️ Mark the date! On May 28-29 2026, we will host and organize the next edition of the Chen Institute Symposia: Brain, Behavior & Beyond.

▶️ This year we will focus on New Horizons in Aging and Neurodegenerative Diseases.

▶️ Stay tuned as we will soon disclose speakers and more!

Photos de deux personnes tenant des bols vides. Crédit image : © AdobeStock - Prostock-studio

🍽 Des scientifiques de l'Institut des Neurosciences Paris-Saclay (CNRS/Université Paris-Saclay) ont montré comment, chez la mouche drosophile, la faim agit sur des circuits cérébraux précis, influençant les comportements face au danger.

▶ www.insb.cnrs.fr/fr/cnrsinfo/...

Our new paper is out!! @jovaniclab.bsky.social @neuropsi.bsky.social

Check out if you are interested in behavior, neuromodulation and neural circuits.

#ResultatScientifique Comment la faim influence-t-elle nos comportements ? Explorer le cerveau de la mouche pour mieux comprendre.

🤝 @cnrs-paris-saclay.bsky.social @univparissaclay.bsky.social @neuropsi.bsky.social
✍️ Tihana Jovanic

👉 buff.ly/6vFH2ZE

Feeding state-dependent neuropeptidergic modulation of reciprocally interconnected inhibitory neurons biases sensorimotor decisions in Drosophila - Nature Communications Neural mechanisms underlying state-dependent flexible selection are not fully understood. Here authors show that NPY homologues in Drosophila larva differentially modulate reciprocally connected inhib...

📄📑 New publication: the Jovanic team @neuropsi.bsky.social & collaborators from @pasteur.fr & @unicologne.bsky.social show that in Drosophila larva 🪱, an homologue of the vertebrate Neuropeptide Y modulates reciprocally connected inhibitory neurons to bias non-feeding decisions.

Learn more 🔽🔽🔽

Neuropeptide dynamics coordinate layered plasticity mechanisms adapting Drosophila circadian behavior to changing environment Neuropeptide-guided plasticity of the clock neuron network operation enables behavioral adaptation to seasonal changes.

A study from the Rouyer group shows how fruit flies 🪰 use a neuropeptide to translate environmental information into changes in neuropeptide levels, to adapt their sleep-wake behavior to summer days 😴😎.

Deadline approaching: 22 Aug 2025!!!
Tenure-track Junior Professor (CPJ) in Multi-omics Cell Atlases of Brain Development
@neuropsi.bsky.social @univparissaclay.bsky.social
Details: www.universite-paris-saclay.fr/sites/defaul...
Apply via ODYSSEE: odyssee.enseignementsup-recherche.gouv.fr

Les souris ont aussi une représentation cognitive riche de leur corps L’illusion de la « main en caoutchouc » montre que la manipulation astucieuse de perceptions visuelles et tactiles peut nous convaincre en quel

Les souris ont-elles aussi une représentation cognitive de leur corps ?

🤝 @cnrs-paris-saclay.bsky.social @univparissaclay.bsky.social @lucestebanez.bsky.social @touchmovelab.bsky.social @neuropsi.bsky.social

👉 Lire l'article dans @plosbiology.org
buff.ly/2JK2msI

Le projet Neurocontrol : où les neurosciences rencontrent l’automatique – MITI Retrouver l'interview des porteurs du projet Neurocontrol, fruit d’une collaboration entre neuroscientifiques et automaticiens

🎉 L'interdisciplinarité est à l'oeuvre dans notre institut.

🤝 Nos liens forts avec la communauté des ingénieurs du L2S @centralesupelec.bsky.social nous valent le label PRIME de @cnrs.fr !

C'est une grande tristesse d'apprendre la mort d'Heather... C'était une personne d'une grande gentillesse et bienveillance, toujours à l'écoute et toujours disponible. Toutes mes pensées vont à sa famille et ses collègues.

🔬🐁 We have a new position open!

➡️ Our "Chaire Professeur Junior" position focuses on multi-omics during brain development. This research-heavy position follows a tenure-track scheme, leading to a full professor position.

🗓️ Application deadline: 22/08/2025

A portrait of Heather McLean

We are very sad to announce our loss of Heather McLean, assistant professor at @neuropsi.bsky.social, who passed away on the 16th of June. She will be fondly remembered by her students, fellow researchers and colleagues.