Cardiovascular Pathology

What’s the pathologic process happening in the small and large intestine here? Answer here: www.sciencedirect.com/science/arti...

#pathsky #cardiosky #medsky

The moment all cardiovascular pathologists have been waiting for….
The NEW criteria for the diagnosis of lymphocytic myocarditis on surgical and autopsy specimens are now available. Open access for a limited period of time at: www.sciencedirect.com/science/arti...

#pathsky #medsky #cardiosky

Can you identify the pathogen in this pulmonary valve vegetation? Answer here: www.sciencedirect.com/science/arti...
#pathsky #medsky #cardiosky

#medsky #pathsky #cardiosky

Open Access! This thorough report examines the effects of truncating variants of TTN and BAG3 in a single family. Available at: www.sciencedirect.com/science/arti...

NEW open access alert!! Available for a limited time at: www.sciencedirect.com/science/arti...

#pathsky #cardiosky #medsky

#pathsky #medsky #cardiosky

This mass was resected from the mitral valve of a 73-yr-old man…any guesses? (Hint: left lower IHC is MDM2). Answer available here:

www.sciencedirect.com/science/arti...

Cardiac fibrosis is a common finding in many myocardial diseases, including ischemia, myocarditis, and cardiomyopathies. These authors review epigenetic regulation of cardiac fibrosis and potential implications for clinical care: www.sciencedirect.com/science/arti...
#cardiosky #pathsky #medsky

What’s the cardiac disease depicted in this EM image? Give it a shot in the comments!
Answer here: www.sciencedirect.com/science/arti...
#cardiacsky #pathsky #medsky

Have you ever been asked to diagnose Takotsubo Cardiomyopathy postmortem? This review article addresses the difficulties and limitations: www.sciencedirect.com/science/arti...

#medsky #pathsky #cardiosky

Researchers at Boston Children’s Hospital and Harvard Medical School have managed to preserve rare specimens of congenital heart disease and create an online atlas. Read their process (and find the link to the atlas) here: www.sciencedirect.com/science/arti...
#cardiosky #pathsky #medsky

NEW OPEN ACCESS:
The impact of moderate and high intensity endurance exercise on acute murine coxsackievirus B3 myocarditis

www.sciencedirect.com/science/arti...
#cardiosky #myocarditis #pathsky #medsky

Please join us on Friday, May 9th at 8am EST!
Mass General Brigham, in collaboration with The Christ Hospital, will be hosting the ADVANCE Lecture Series: Advancing Women's Heart Health.
This month's speaker will be Emily Lau, MD, MPH @emilyswlau.bsky.social 🩺

🫀 Coronary microvascular dysfunction may be the key to preventing & treating HFpEF.

Learn how CMD influences pathophysiology & what it means for future care.

🔗 ow.ly/Hk0150VOQxi

#HFpEF #CMD #HeartFailure #Cardiology #CVDPrevention #CardioSky #MedSky

#pathsky #medsky #cardiosky

Were you taught in medical school that patients with bicuspid aortic valves developed aortic aneurysms because of ‘turbulent blood flow’? This article helps to correct that misperception (hint: it involves embryology). www.sciencedirect.com/science/arti...

Survival Outcomes After Sudden Cardiac Arrest in Young Competitive Athletes From the United States:

In Jan 2023, Damar Hamlin collapsed during NFL game & survived thanks to immediate CPR & AED use. But what do survival outcomes look like for young athletes across the U.S.? www.jacc.org/doi/10.1016/...
New @jaccjournals.bsky.social Deep Dive episode explores the data. www.jacc.org/digital-cont...

New article alert! This original study examines mortality trends in heart failure and COPD-associated heart failure. Open access for the next 30 days only: www.sciencedirect.com/science/arti...
#pathsky #cardiosky #medsky

What’s happening in this endomyocardial biopsy? Find the answer here: www.sciencedirect.com/science/arti...
#medsky #pathsky #cardiosky

Attention autopsy, forensic, and cardiovascular pathologists! Did you miss this 2023 Consensus Statement with recommended examination procedures for sudden cardiac death? It’s still available at: www.sciencedirect.com/science/arti...
#medsky #pathsky #cardiosky

Attention autopsy, forensic, and cardiovascular pathologists! Did you miss this 2023 Consensus Statement with recommended examination procedures for sudden cardiac death? It’s still available at: www.sciencedirect.com/science/arti...
#medsky #pathsky #cardiosky

#pathsky #cardiologysky #medsky

Open Access Alert! What are the causes of biomaterial degeneration in patients with congenital heart disease? www.sciencedirect.com/science/arti...

Is the concept of a ‘vulnerable patient’ more useful than a ‘vulnerable plaque’? This thoughtful review examines this question:
www.sciencedirect.com/science/arti...
#pathsky #medsky

Absolutely! The specific mechanisms, though (ie infection vs rejection), can be informative as a way of improving post-transplant care. Unfortunately many organ recipients never have autopsies…

#pathsky #medsky

Autopsies are still absolutely necessary to advance our understanding of disease, and better treat living patients. Full article available here: www.sciencedirect.com/science/arti...

22/435 #SpontaneousCoronaryArteryDissection 👤also have #AorticDissection in 1st-/2nd-degree relatives

16F+1M probands SCAD+AD families studied

Pathogenic (or likely) variants
SMAD3
COL3A1
CBS H2S synthesis
OAT GABA synthesis
NEXN
DYSF myopathy
CYP7B1

#JAHA 2025
www.ahajournals.org/doi/10.1161/...

Can you identify this tumor in a lower pulmonary vein? See the answer at: www.sciencedirect.com/science/arti...
#pathsky #medsky