Dan Lurie

U-Miami has a postdoctoral mentored research training program in Alzheimer's / neurodegeneration, with 2 years of funding for fellows. If you're interested in my lab and applying cognitive neuroscience and precision neuroimaging methods to studying AD, please reach out! mbi-umiami.org/training/

This metaphorical illustration reimagines a hidden view of the brain of a patient with hemispherotomy. In the absence of subcortical activating inputs, the disconnected cortex defaults to a sleep-like state, marked by slow-wave EEG activity and here evocatively represented as night. By contrast, the intact hemisphere, still integrated with subcortical structures, sustains wakefulness and a bright inner world capable of environmental interaction, reflected in faster EEG rhythms. The image underscores the divergence of cortical states after hemispheric isolation. The image was created by Michele A. Colombo, the first author of the paper, through digital photo manipulation combining drawings with real neuroimaging and electrophysiological data.

#Hemispherotomy is a surgical treatment for #epilepsy by disconnecting a portion of the #cortex. Michele Colombo, Jacopo Favaro, @anilseth.bsky.social, Marcello Massimini &co show that the isolated cortex has #EEG patterns resembling deep #sleep or #anesthesia @plosbiology.org 🧪 plos.io/3J9ci8X

Dense Phenotyping of Human Brain Network Organization Using Precision fMRI The advent of noninvasive imaging methods like functional magnetic resonance imaging (fMRI) transformed cognitive neuroscience, providing insights into large-scale brain networks and their link to cog...

Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization?
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...

#neuroskyence #psychscisky #MedSky
🧵👇

Susan Schneider, David Sahner, Robert Lawrence Kuhn, Eric Schwitzgebel & Mark Bailey, Is AI Conscious? A Primer on the Myths and Confusions Driving the Debate - PhilPapers Artificial intelligence is sparking unprecedented claims about machine minds — but are today’s systems really conscious? In this primer, we disentangle the myths, misconceptions, and confusions fuelin...

New in draft with Susan Schneider, David Sahner, Robert Lawrence Kuhn & Mark Bailey - a primer on central ideas and concepts in the AI consciousness debate. If you're looking for a toehold in the sea of jargon, this might help.

philpapers.org/rec/SCHIAC-22

The Motion Sensitivity and Predictive Utility of Different Estimates of Inter-regional Functional Coupling in Resting-state Functional MRI. https://www.biorxiv.org/content/10.1101/2025.07.13.664614v1

Functional network architecture and dynamics of the somato-cognitive action network https://www.biorxiv.org/content/10.1101/2025.07.16.660604v1

We have argued that the brain’s Action Mode Network controls functions required for goal-directed behavior. www.nature.com/articles/s41...

Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...

If you have 10-20 minutes (depends on how fast you are), would you please consider doing this online study on #mentalimagery? It contains a survey & an experiment where you look at pictures and you respond what you see:
#psychscisky #neuroskyence #visionscience

tstbl.co/820-917

Had a dream last night where we were living in a fascist sci-fi future with flying cars and laser blasters, but you got a K Award if you were an effective enough member of the resistance against the secret police.

I feel like my sleeping brain needs to work on the subtlety of my dream metaphors.

Exclusive | New Yorker dresses as ‘washed up scum’ Andrew Cuomo in Mermaid Parade “I’m trying to get reelected on Tuesday and I thought I’d bring my message to the voters,” the man who only called himself “washed up scum,” sarcastically told The Post.

Hey NYC friends!

If you haven't yet voted in the Democratic mayoral primary:

1) Go vote today!

2) Remember not to rank Cuomo!

nypost.com/2025/06/21/u...

(Excellent Mermaid Parade costume made by a friend.)

Cholinergic feedback for modality- and context-specific modulation of sensory representations The brain’s ability to prioritize sensory information is crucial for adaptive behavior, yet its mechanisms remain unclear. We investigated basal forebrain cholinergic neurons modulating olfactory bulb...

Our new paper is out in Science.

We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.

Congrats to Bin for the great thesis, and the team!

www.science.org/doi/10.1126/...

Cholinergic modulation of dopamine release drives effortful behavior https://www.biorxiv.org/content/10.1101/2025.06.18.660394v1

Is "salsa pattern" (which I assume means a three-class high/medium/low solution?) common terminology? I like it.

Sign the Petition Preserve the Open Science Room at the Organization for Human Brain Mapping Annual Meeting

The Open Science room is an important part of the OHBM meeting experience, and not just for people who identify as part of the open science community.

Unfortunately, the future of the Open Science room is at risk.

Read more here and sign the petition to @ohbmofficial.bsky.social leadership.

Passed this the other day while out and about but didn't realize what it was. Awesome to see. More of this in my backyard, yes please.

We need your help!!! 🧠🧪💤

If you are human, you fall asleep at least once a day! What happens in your mind then?

Scientists know actually very little about this private moment.

We propose a 20-min survey to get as much data as possible!

Here is the link:
redcap.link/DriftingMinds

Home What can we do with functional MRI data? For many years, fMRI has been used to discover population-level patterns of brain function, organization and connectivity, and to understand differences in t...

Looking forward to #OHBM2025 in Brisbane next week! My lab is recruiting a postdoc & neuroimaging analyst/developer to support our NIH funded work in fMRI-based Alzheimer's biomarker development (NIA R01AG083919). Email or DM if you want to meet up in Brisbane! www.statmindlab.com/join-us

Shattered Science: The Research Lost as Trump Targets NIH Funding The Trump administration cut research funding that sought cures for future pandemics, examined the causes of dementia and tried to prevent HIV transmission. More than 150 researchers shared with ProPu...

Extremists have eviscerated the National Institutes of Health, responsible for 80% of the *world’s* grant investment in biomedical research

The losses are incalculable, but here are several of them

Thank you @propublica.org for documenting this —>

Benchmarking methods for mapping functional connectivity in the brain - Nature Methods In this Analysis, Liu et al. benchmark more than 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure–function coupling and behavio...

An Analysis of 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure-function coupling and behavior prediction highlights their effectiveness for neurophysiological applications.

www.nature.com/articles/s41...

I taught a graduate course on executive function (EF) in the spring. Before I forget, I thought I'd tell you about the readings students liked the best (at the end of the semester, I asked students to vote for their favorite papers, excl. any of mine). Here are the top vote getters. 🧵 (1/6)

Thanks for the insights, Blaise! Always great to hear what an expert thinks.

The relationship between writing and thinking is a fundamental one and getting more attention given that we can (presumably) offload our writing to AI systems.
I often find that we don't really understand things sufficiently well if we can't write it in ways that others understand.

If you teach cognitive psychology or related topics & are willing to share your favorite teaching resources (e.g., demos, videos), please reply to/quote this post, tag me in a new post, or send me email. I'll compile them, share the list, & keep updating it this summer. Let's inspire each other!

#JNeurosci: Ponce-Alvarez uses publicly available human rs-fMRI and dMRI data to analyze the relationship between timescales, variances, and structural connectivity, while also exploring the underlying mechanisms through connectome-based whole-brain models.
vist.ly/3n5r9ct

Visit Us * Complexity Science Hub CSH offers talented researchers at all career stages the opportunity to join us in Vienna for a scientific visit.

Hey #complexity colleagues 🧪🦋

Can you imagine your next steps at Complexity Science Hub?

We'd like to ease a transition to #Europe across levels of seniority with our new extended, exploration visitor program.

csh.ac.at/engage/resea...
1/3

NSF, NASA and NIH budgets per year, inflation adjusted from 2000-2025 along with the proposed cuts. NSF includes research component only. Massive cuts across all sectors, well below support spanning 25 years.

How bad will it be? Catastrophic.

Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come.

But, this is the WH's *proposed* budget.

Speak up now before it is too late.

(inflation adjusted $-s below)

ASSIGNMENT: COMMENT ON SCHEDULE F

1 week left to comment about Schedule F, potentially making NIH institute and center director essentially political appointees.

www.regulations.gov/commenton/OP...

1/n

Leveraging multivariate information for community detection in functional brain networks - Communications Biology Modeling brain modular structure by accounting for higher-order interactions reveals a novel organization of the transmodal cortex and highlights brain areas with high and low topological specializati...

Niceeeee www.nature.com/articles/s42... Leveraging multivariate information for community detection in functional brain networks | Communications Biology

🚨Preprint!🚨 So excited to share my 1st major study as a postdoc at @holmeslab-bhi.bsky.social!🤘

www.biorxiv.org/content/10.1...

Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇

I can't believe it's taken me almost 37 years of life to realize that muffins are just tiny breakfast cake.