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1/ First preprint from @jdemeul.bsky.social lab 🥳! We present our new multi-modal single-cell long-read method SPLONGGET (Single-cell Profiling of LONG-read Genome, Epigenome, and Transcriptome)! www.biorxiv.org/content/10.1...

10.09.2025 15:48 — 👍 44    🔁 16    💬 1    📌 1

Long-read single-cell genome, transcriptome and open chromatin profiling links genotype to phenotypes. https://www.biorxiv.org/content/10.1101/2025.09.08.674950v1

09.09.2025 07:35 — 👍 12    🔁 4    💬 0    📌 0

The Guardian view on RFK Jr’s vaccine cuts: an assault on science from a politician unfit for his office | Editorial Editorial: The decision by the US health and human services secretary to remove mRNA research funding is ill-informed and dangerous

The Guardian view on RFK Jr’s vaccine cuts: an assault on science from a politician unfit for his office

bit.ly/45Azvbf

12.08.2025 13:25 — 👍 6    🔁 5    💬 0    📌 0

Our spotlight winner, Ruben Cools, presented his full talk exploring how they are bridging genotype and phenotype through long Oxford Nanopore read, single-molecule multiomics. #NanoporeConf

22.05.2025 16:02 — 👍 8    🔁 6    💬 0    📌 0

Integrative Assessment of Total and Intact HIV-1 Reservoir by a 5-Region Multiplexed Rainbow DNA Digital PCR Assay AbstractBackground. Persistent latent reservoirs of intact HIV-1 proviruses, capable of rebounding despite suppressive antiretroviral therapy (ART), hinder

Integrative Assessment of Total and Intact #HIV-1 Reservoir by a 5-Region Multiplexed Rainbow DNA Digital PCR Assay academic.oup.com/clinchem/art... (open access)

07.01.2025 15:24 — 👍 1    🔁 1    💬 0    📌 0

4/ Special thanks to our dedicated study participants at
UZ Gent , the co-authors, and members of the HIV Cure Research Center!

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3/ Our paper also showcases the scalability of HIV-PULSE. Read about how this single assay identified over 1,300 distinct HIV-1 genomes, shedding light on viral diversity & reservoir composition and opening doors to new discoveries!

30.10.2023 11:48 — 👍 0    🔁 0    💬 1    📌 0

2/ Our HIV-PULSE assay brings an innovative, cost-effective approach for generating HIV-1 proviral genomes. By harnessing Nanopore's long-read tech, we offer near full-length sequencing at a reduced cost per genome while maintaining sensitivity & accuracy.

30.10.2023 11:47 — 👍 0    🔁 0    💬 1    📌 0

HIV-PULSE: a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome c... Abstract. A deep understanding of the composition of the HIV-1 reservoir is necessary for the development of targeted therapies and the evaluation of curative e

1/ Excited to announce the publication of my paper on the HIV-PULSE assay in Nucleic Acids Research! academic.oup.com/nar/advance-...

30.10.2023 11:47 — 👍 5    🔁 1    💬 1    📌 0